Early Phase 1 Cognitive Clinical Trials

8 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 18 of 8 trials

Recruiting
Early Phase 1

Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease

DepressionDepressive SymptomsAlzheimer Disease+1 more
Johns Hopkins University20 enrolled1 locationNCT04123314
Recruiting
Early Phase 1

Effects of Nicotinamide Riboside on Bioenergetics and Oxidative Stress in Mild Cognitive Impairment/Alzheimer's Dementia

Mild Cognitive ImpairmentMild Alzheimer Disease
Mclean Hospital50 enrolled1 locationNCT04430517
Recruiting
Early Phase 1

Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease

Alzheimer DiseaseMild Cognitive ImpairmentLogopenic Progressive Aphasia+1 more
Massachusetts General Hospital30 enrolled1 locationNCT06538311
Recruiting
Early Phase 1

Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease

Cognitive ChangeSleepMild Cognitive Impairment+2 more
University of Pittsburgh116 enrolled1 locationNCT05138848
Recruiting
Early Phase 1

Pharmacological Modulation of Brain Oscillations in Memory Processing

EpilepsySeizuresMemory Disorders+2 more
University of Texas Southwestern Medical Center60 enrolled1 locationNCT05594017
Recruiting
Early Phase 1

Attentional Mechanisms in SCD

Subjective Cognitive Decline
Vanderbilt University Medical Center80 enrolled1 locationNCT06002477
Recruiting
Early Phase 1

Cannabidiol Solution for the Treatment of Behavioral Symptoms in Older Adults With Mild Cognitive Impairment or Alzheimer's Dementia

AnxietyAlzheimer DiseaseMild Cognitive Impairment (MCI) Due to Alzheimer's Disease+1 more
Mclean Hospital12 enrolled1 locationNCT04075435
Recruiting
Early Phase 1

Working Memory Training for People Aging with HIV

Cognitive Change
Northeastern University80 enrolled1 locationNCT06699927