Phase 4 Cognitive Clinical Trials
31 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 31 trials
Recruiting
Phase 4
A Study Testing How Well the Drug Extract of Ginkgo Biloba Leaves Tablets Works for People With Memory or Thinking Problems After a Stroke When Added to Standard Treatment
Ischemic Stroke HospitalizedImpairment, Cognitive
Dr. Willmar Schwabe GmbH & Co. KG400 enrolled30 locationsNCT07220538
Recruiting
Phase 4
Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
Cognitive FunctionMotor FunctionContrast Media
Guerbet2,076 enrolled51 locationsNCT04373564
Recruiting
Phase 4
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients
ConfusionCognitive DysfunctionMolecular Mechanisms of Pharmacological Action+14 more
Sunnybrook Health Sciences Centre2,400 enrolled8 locationsNCT04289142
Recruiting
Phase 4
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
Cardiovascular DiseasesDementiaCognitive Impairment, Mild
Duke University20,000 enrolled103 locationsNCT04262206
Recruiting
Phase 4
Butylphthalide for Cognitive Impairment in Elderly Patients With Focal Epilepsy
Cognitive ImpairmentFocal Epilepsy
First Affiliated Hospital of Wenzhou Medical University220 enrolled1 locationNCT07193277
Recruiting
Phase 4
The Effect of Desflurane Versus Sevoflurane Versus Propofol on Postoperative Delirium
Postoperative DeliriumPostoperative Cognitive DysfunctionMajor Noncardiac Surgery
Medical University of Vienna1,332 enrolled2 locationsNCT05990790
Recruiting
Phase 4
The Efficacy of Dexamethasone in Combination With N-acetylcysteine in Preventing Neurocognitive Sequelae Due to Carbon Monoxide Poisoning
Carbon Monoxide PoisoningDelayed Neurocognitive Sequelae
China Medical University Hospital128 enrolled1 locationNCT06811675
Recruiting
Phase 4
Remimazolam for Cataract Surgery
Cognitive ImpairmentCataract Surgery
University of California, Los Angeles120 enrolled1 locationNCT05980117
Recruiting
Phase 4
The Study of Ginkgo Leaf Dropping Pills and Huperzine a Injection Combined with Median Nerve Electrical Stimulation in the Treatment of Cognitive Impairment After Brain Injury
Cognitive Impairment After Brain Injury
Wanbangde Pharmaceutical Group Co., LTD50 enrolled1 locationNCT06704334
Recruiting
Phase 4
Fufang Congrong Yizhi Capsules (FCYC) of Cognitive Impairment After Intracerebral Hemorrhage
Cognitive ImpairmentIntracerebral Hemorrhage
Qinhuangdao Hospital of Traditional Chinese Medicine200 enrolled6 locationsNCT06673602
Recruiting
Phase 4
Dexmedetomidine or Clonidine Infusion for Prevention of Delirium After Open Heart Surgery
Cognitive DeclineFrailtyDelirium
Oslo University Hospital900 enrolled5 locationsNCT05029050
Recruiting
Phase 4
Dexmedetomidine on Postoperative Cognitive Dysfunction and Serum Tau-217 Protein.
Cognitive Impairment
Minia University Hospital94 enrolled1 locationNCT06366412
Recruiting
Phase 4
Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study
AnesthesiaNeurocognitive Disorders
Oregon Health and Science University260 enrolled1 locationNCT06036095
Recruiting
Phase 4
A Real World Study of the Effect of Early PEG-rhGH Therapy on Cognitive Development of SGA Infants
Growth Hormone TreatmentSmall for Gestational Age InfantCognitive Developmental Disorder
Tongji Hospital138 enrolled1 locationNCT05144035
Completed
Phase 4
Comparison of the effect of Preoperative Pregabalin and Duloxetine on Postoperative Pain and Cognitive Function After Spinal Surgery
Cognitive function after elective laminectomy for lumbar disc herniationPostoperative pain after elective decompression laminectomy for lumbar disc herniation
Basak ALTIPARMAK90 enrolled1 locationACTRN12618000521224
Completed
Phase 4
Pharmaceutical enhancement of complex problem-solving in healthy adults
Cognitive enhancement
The University of Melbourne32 enrolled1 locationACTRN12617001544369
Active
Phase 4
Sleep and speech: Objectively monitoring the residual effects of sleep-promoting compounds
Cognitive detriment due to residual effects to the central nervous system after using zolpidem or temazepam.
Monash University50 enrolled1 locationACTRN12616000033448
Completed
Phase 4
Perioperative Ketamine to Reduce Postoperative Delirium and Depression - The RECOGNISED Study
DepressionDeliriumPostoperative Cognitive Dysfunction
St Vincent's Hospital145 enrolled1 locationACTRN12615001074583
Completed
Phase 4
A randomized trial of midazolam versus placebo on cognitive recovery in adult patients following elective outpatient colonoscopy using postoperative quality of recovery scale.
Cognitive recovery following anaesthesia
Usha Gurunathan400 enrolled2 locationsACTRN12615000625572
Completed
Phase 4
The ASPREE NEURO study: Does daily, low dose aspirin in adults aged 70 years and over affect age related changes in brain small blood vessels seen on MRI over time, and do these changes improve prediction of stroke risk or cognitive decline?
Cerebral Microhaemorrhage (CMH)Cognitive DeclineStroke+1 more
Monash University600 enrolled1 locationACTRN12613001313729