Phase 4 Colitis Clinical Trials
22 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 22 trials
Recruiting
Phase 4
A Study of Filgotinib 200 mg in Korean Participants With Moderately to Severely Active Ulcerative Colitis Under Routine Clinical Practice
Ulcerative Colitis
Eisai Korea Inc.94 enrolled19 locationsNCT06964113
Recruiting
Phase 4
A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting
Crohn's DiseaseUlcerative Colitis
Takeda400 enrolled98 locationsNCT06581328
Recruiting
Phase 4
Upadacitinib Versus Infliximab as Second-Line Treatment for Acute Severe Ulcerative Colitis（UPRISE）
Acute Severe Ulcerative Colitis
Xijing Hospital of Digestive Diseases226 enrolled4 locationsNCT07550673
Recruiting
Phase 4
Comparative Effectiveness of Upadacitinib vs Corticosteroids as First-Line Therapy for Acute Severe Ulcerative Colitis（UPFRONT）
Acute Severe Ulcerative Colitis
Yongquan Shi46 enrolled4 locationsNCT07546097
Recruiting
Phase 4
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Ulcerative Colitis
Takeda65 enrolled49 locationsNCT06095128
Recruiting
Phase 4
Upadacitinib Combined With Corticosteroids vs Corticosteroid Monotherapy Induction for Inpatients and Outpatients With Acute Severe Ulcerative Colitis
Ulcerative Colitis Acute
Berinstein, Jeffrey110 enrolled1 locationNCT07258771
Recruiting
Phase 4
De-escalation of Ustekinumab Therapy in Patients With Crohn's Disease and Ulcerative Colitis
Ulcerative Colitis (UC)Crohn Disease (CD)
McGill University Health Centre/Research Institute of the McGill University Health Centre115 enrolled1 locationNCT07303686
Recruiting
Phase 4
Efficacy of Top-down Therapy With Mirikizumab Versus Standard of Care With Azathioprine in Patients With Newly Diagnosed Moderate-to-severe Ulcerative Colitis
Ulcerative Colitis (UC)
University Hospital Schleswig-Holstein300 enrolled1 locationNCT07235904
Recruiting
Phase 4
Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis
Ulcerative Colitis
Bausch Health Americas, Inc.70 enrolled4 locationsNCT04314375
Not Yet Recruiting
Phase 4
Upadacitinib versus Oral Corticosteroid for Induction of Transmural Remission in Moderate to Severe Ulcerative Colitis and Crohn’s Disease Flares - INDUCE
Crohn's DiseaseUlcerative ColitisInflammatory Bowel Disease
Mater Misericordiae Ltd80 enrolled1 locationACTRN12625000861459
Recruiting
Phase 4
Study of the Effect of Vedolizumab on Intestinal Microecological Changes and Its Efficacy in the Treatment of Ulcerative Colitis
Ulcerative Colitis
Second Affiliated Hospital, School of Medicine, Zhejiang University30 enrolled1 locationNCT05481619
Recruiting
Phase 4
Impact of Anti-TNF, Vedolizumab and Tofacitinib on Aortic Stiffness, Carotid Intima-media Thickness and Cardiovascular Risk of Patients With Ulcerative Colitis
Ulcerative Colitis
Centre Hospitalier Universitaire, Amiens100 enrolled1 locationNCT04743518
Recruiting
Phase 4
Feasibility Pilot Sequential Multiple Assignment Randomized Trial (SMART) for Acute Severe Ulcerative Colitis
Ulcerative Colitis Acute
Berinstein, Jeffrey162 enrolled1 locationNCT05867329
Recruiting
Phase 4
Effect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic Events
Ulcerative ColitisThromboembolism
Fundación de Investigación Biomédica - Hospital Universitario de La Princesa30 enrolled1 locationNCT05313620
Recruiting
Phase 4
Bowel Preparation for Colonoscopy Among Individuals With Crohn's and Ulcerative Colitis Disease.
Crohn DiseaseUlcerative Colitis
University of Manitoba418 enrolled1 locationNCT06298461
Recruiting
Phase 4
The Efficacy and Safety of Combining Probiotic VSL#3 With Vedolizumab for the Treatment of Moderate Ulcerative Colitis
Ulcerative Colitis
Second Affiliated Hospital, School of Medicine, Zhejiang University100 enrolled12 locationsNCT06609447
Recruiting
Phase 4
Subcutaneous Infliximab After A Previous Intravenous Dose Optimization
Inflammatory Bowel DiseasesCrohn DiseaseUlcerative Colitis
Belgian Inflammatory Bowel Disease Research and Development (BIRD) VZW275 enrolled15 locationsNCT06113913
Recruiting
Phase 4
Top Down Versus Step up in Pediatric Ulcerative Colitis
Ulcerative ColitisChildrenInfliximab
Children's Hospital of Fudan University40 enrolled1 locationNCT04999228
Recruiting
Phase 4
A Trial COmparing staNdard of Care Versus Treat to Target With telemonitoRing and Patient Education in Patients With Ulcerative cOlitis Initiating Adalimumab
Ulcerative Colitis
Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives238 enrolled24 locationsNCT04183608
Completed
Phase 4
Antibody response to COVID-19 vaccination in immunosuppressed patients with autoimmune disease
Crohn's DiseaseCOVID-19Ulcerative Colitis
Dr Ai Tran100 enrolled2 locationsACTRN12621000661875