Colorectal Neoplasm Clinical Trials

1 recruiting

Colorectal Neoplasm Trials at a Glance

64 actively recruiting trials for colorectal neoplasm are listed on ClinicalTrialsFinder across 6 cities in 40 countries. The largest study group is Not Applicable with 15 trials, with the heaviest enrollment activity in Houston, Barcelona, and Grand Rapids. Lead sponsors running colorectal neoplasm studies include Janssen Research & Development, LLC, Cancer Research UK, and National Cancer Institute (NCI).

Browse colorectal neoplasm trials by phase

Treatments under study

About Colorectal Neoplasm Clinical Trials

Looking for clinical trials for Colorectal Neoplasm? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Colorectal Neoplasm trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Colorectal Neoplasm clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 64 trials

Recruiting

Epidemiological and Molecular Colorectal Cancer Registry

Colorectal Neoplasms
Hospital Italiano de Buenos Aires2,100 enrolled1 locationNCT02781337
Recruiting
Phase 2

Delayed Systemic Therapy Following Destructive Local Treatment of Pulmonary Oligometastases After No Evidence of Disease (NED) in Colorectal Cancer.

Colorectal Neoplasms Malignant
Shandong Cancer Hospital and Institute22 enrolled1 locationNCT06778382
Recruiting
Phase 3

Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66)

Colorectal Neoplasms
Merck Sharp & Dohme LLC100 enrolled32 locationsNCT05239741
Recruiting
Phase 1

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Advanced Breast CancerAdvanced Solid TumorsMetastatic Pancreatic Cancer+3 more
National Cancer Institute (NCI)116 enrolled2 locationsNCT04222413
Recruiting

Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer

CholangiocarcinomaPancreas CancerColorectal Neoplasms+2 more
National Cancer Institute (NCI)1,800 enrolled1 locationNCT01915225
Recruiting
Phase 3

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Colorectal NeoplasmsNeoplasms by SiteGastrointestinal Neoplasms+7 more
Pfizer800 enrolled156 locationsNCT07222800
Recruiting
Phase 1

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

Colorectal Neoplasms
Seagen, a wholly owned subsidiary of Pfizer914 enrolled44 locationsNCT06131840
Recruiting
Phase 1

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

Breast NeoplasmsColorectal NeoplasmsProstate Neoplasm+2 more
Eli Lilly and Company421 enrolled28 locationsNCT07114601
Recruiting
Phase 1

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

Breast NeoplasmsCholangiocarcinomaOvarian Neoplasms+4 more
Eli Lilly and Company241 enrolled28 locationsNCT07213791
Recruiting
Phase 1

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Colorectal NeoplasmsCarcinoma, Pancreatic Ductal
Pfizer330 enrolled28 locationsNCT06447662
Recruiting
Not Applicable

The Impact of Image-Assisted Colonoscope on Patient Experience, Physician Workload, and Examination Quality

Colorectal Cancer ScreeningColonic Polyps/Colonoscopy/Colorectal NeoplasmsDifficult Colonoscopy+1 more
DONG WU200 enrolled1 locationNCT07541924
Recruiting
Phase 1

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

Colorectal NeoplasmsGastrointestinal Neoplasms
Janssen Research & Development, LLC220 enrolled10 locationsNCT06663319
Recruiting
Phase 1

A Study of JNJ-95437446 in Participants With Advanced-Stage Solid Tumors

Colorectal Neoplasms
Janssen Research & Development, LLC380 enrolled9 locationsNCT07107230
Recruiting
Phase 3

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Colorectal Neoplasms
Janssen Research & Development, LLC1,000 enrolled234 locationsNCT06662786
Recruiting
Phase 3

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

Colorectal Neoplasms
Janssen Research & Development, LLC700 enrolled234 locationsNCT06750094
Recruiting
Phase 3

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

Colorectal Neoplasms
Seagen, a wholly owned subsidiary of Pfizer400 enrolled382 locationsNCT05253651
Recruiting
Not Applicable

Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.

Colorectal NeoplasmsColonoscopyIntestinal Polyps
University Hospital, Bordeaux592 enrolled13 locationsNCT07299071
Recruiting
Phase 2

PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma

Colorectal NeoplasmsIntrahepatic Cholangiocarcinoma (Icc)Metastatic Colorectal Cancer (Mcrc)+1 more
National Cancer Institute (NCI)70 enrolled1 locationNCT05286814
Recruiting

DANISH.MRD: Danish Assessment of Minimal Residual Disease by Liquid Biopsies

Colorectal Neoplasms
University of Aarhus1,600 enrolled10 locationsNCT06076811
Recruiting
Not Applicable

Randomized Trial Comparing Fecal Testing (FIT) to Colonoscopy for Post-polypectomy Surveillance

Colorectal Neoplasms
Sorlandet Hospital HF4,000 enrolled1 locationNCT06983639