Complex Regional Pain Syndromes Clinical Trials

14 recruitingLast updated: May 13, 2026

There are 14 actively recruiting complex regional pain syndromes clinical trials across 7 countries. Studies span Not Applicable. Top locations include Cincinnati, Ohio, United States, New York, New York, United States, Glostrup, Region Sjælland, Denmark. Updated daily from ClinicalTrials.gov.


Complex Regional Pain Syndromes Trials at a Glance

14 actively recruiting trials for complex regional pain syndromes are listed on ClinicalTrialsFinder across 6 cities in 7 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in Cincinnati, New York, and Glostrup. Lead sponsors running complex regional pain syndromes studies include Children's Hospital Medical Center, Cincinnati, Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape, and Bo Biering-Soerensen.

Browse complex regional pain syndromes trials by phase

Treatments under study

About Complex Regional Pain Syndromes Clinical Trials

Looking for clinical trials for Complex Regional Pain Syndromes? There are currently 11 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Complex Regional Pain Syndromes trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Complex Regional Pain Syndromes clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 114 of 14 trials

Recruiting
Not Applicable

Prednisone for CRPS in Distal Radius Fracture

Distal Radius FracturesComplex Regional Pain Syndromes
University of British Columbia40 enrolled1 locationNCT06453447
Recruiting
Not Applicable

Perineural Incobotulinumtoxin-A for Complex Regional Pain Syndrome - An Open-label Feasibility Study

CRPS (Complex Regional Pain Syndromes)CRPS (Complex Regional Pain Syndrome) Type ICRPS Type II
Bo Biering-Soerensen20 enrolled1 locationNCT07473635
Recruiting
Not Applicable

Intermittent Dosing of Dorsal Root Ganglion Stimulation as an Alternate Paradigm to Continuous Low-Frequency Therapy

Peripheral NeuropathyCRPS (Complex Regional Pain Syndromes)radiculopathy
Rush University Medical Center30 enrolled1 locationNCT04909138
Recruiting
Not Applicable

Pulsed Electromagnetic Fields (PEMFS) in Complex Regional Pain Syndrome Type i (CRPS-I) of the Foot (PeCFoA)

Foot DiseasesComplex Regional Pain SyndromesPain, Joint+1 more
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari28 enrolled1 locationNCT05922618
Recruiting

Infrared Images for Spinal Cord Stimulation in Complex Regional Pain Syndrome Patients

Complex Regional Pain Syndromes
Hospital for Special Surgery, New York12 enrolled1 locationNCT05777889
Recruiting

Role of the Gut Microbiome in Complex Regional Pain Syndrome

Complex Regional Pain Syndromes
Washington University School of Medicine140 enrolled1 locationNCT03612193
Recruiting
Not Applicable

Closed Loop Spinal Cord Stimulation for Complex Regional Pain Syndrome

Complex Regional Pain Syndromes
Scripps Health32 enrolled1 locationNCT06421350
Recruiting
Not Applicable

Impact of Compression Garments on Pain in Patients With Complex Regional Pain Syndrome of the Upper Limbs.

Complex Regional Pain Syndromes
Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape60 enrolled1 locationNCT05034835
Recruiting
Not Applicable

The Effectiveness of Conservative Treatment in Patients With Complex Regional Pain Syndrome.

CRPS (Complex Regional Pain Syndromes)
Oulu University Hospital156 enrolled1 locationNCT07208825
Recruiting
Not Applicable

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

Post-herpetic neuralgiaPain, PostoperativeNerve Injury+6 more
University of California, San Francisco12 enrolled1 locationNCT04144972
Recruiting
Not Applicable

Supraspinal Processing of Sensory Aspects of Pain

Musculoskeletal PainFibromyalgiaFunctional Abdominal Pain Syndrome+2 more
Children's Hospital Medical Center, Cincinnati350 enrolled1 locationNCT05814497
Recruiting
Not Applicable

TMS for Complex Regional Pain Syndrome

Complex Regional Pain Syndromes
Stanford University40 enrolled1 locationNCT03137472
Recruiting

Spatially Transcriptomics Reveals Molecular Signatures in CRPS

Complex Regional Pain Syndromes
Seoul National University10 enrolled1 locationNCT05986461
Recruiting

Markers of Trajectory in Pediatric CRPS

Complex Regional Pain Syndromes
Children's Hospital Medical Center, Cincinnati126 enrolled1 locationNCT03838107