Concussion Clinical Trials

78 recruitingLast updated: June 18, 2026

There are 78 actively recruiting concussion clinical trials across 13 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3. Top locations include Pittsburgh, Pennsylvania, United States, Philadelphia, Pennsylvania, United States, Calgary, Alberta, Canada. Updated daily from ClinicalTrials.gov.


Concussion Trials at a Glance

78 actively recruiting trials for concussion are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Not Applicable with 45 trials, with the heaviest enrollment activity in Pittsburgh, Philadelphia, and Calgary. Lead sponsors running concussion studies include University of Pittsburgh, Curtin University, and Children's Hospital of Philadelphia.

Browse concussion trials by phase

Treatments under study

About Concussion Clinical Trials

Looking for clinical trials for Concussion? There are currently 31 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Concussion trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Concussion clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 78 trials

Recruiting
Not Applicable

Use of Tinted Contact Lenses for Concussion-Related Light Sensitivity

Concussion, MildPhotophobiaContact Lens
University of Alabama at Birmingham60 enrolled1 locationNCT07223086
Recruiting
Not Applicable

Pro-2-Cool Pivotal Trial II

Concussion, Mild
TecTraum Inc.66 enrolled3 locationsNCT06929923
Recruiting
Not Applicable

GyroStim for Post Concussion Syndrome

Post-Concussion Syndrome
Neuroscience Group128 enrolled1 locationNCT07527663
Recruiting

The COSP-RBD Study: Concussions and Contact Sports in RBD vs Controls

Concussion, BrainREM Sleep Behavior Disorder
Guy's and St Thomas' NHS Foundation Trust140 enrolled1 locationNCT06270290
Recruiting
Not Applicable

REhabilitation of MEMory Symptoms After BRain Concussion

Mild Traumatic Brain InjuryConcussion, Brain
University of British Columbia184 enrolled8 locationsNCT06956417
Recruiting
Not Applicable

A New Generation of Magnetoencephalographs for High Speed Functional Brain Imaging

Healthy VolunteersMild Concussion
Hospices Civils de Lyon80 enrolled2 locationsNCT06244472
Recruiting
Not Applicable

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

InsomniaTraumatic Brain InjuryDepression+7 more
Johns Hopkins University360 enrolled5 locationsNCT05663034
Recruiting
Not Applicable

Interest of the 7 Tesla MRI in the Diagnosis of Post-concussion Syndromes Among Patients With Mild Traumatic Brain Injury

Post-Concussion Syndrome
Poitiers University Hospital100 enrolled1 locationNCT04982562
Recruiting
Not Applicable

Facilitating Access to Specialty Treatment

Mild Traumatic Brain InjuryConcussion, MildConcussion, Intermediate+1 more
Children's Hospital of Philadelphia210 enrolled1 locationNCT05741411
Recruiting
Not Applicable

Impact of a Paced Breathing Exercise Intervention on Autonomic Nervous System Function After Pediatric Concussion (Acute Phase)

Concussion / Mild Traumatic Brain Injury
McGill University Health Centre/Research Institute of the McGill University Health Centre20 enrolled1 locationNCT07572734
Recruiting
Phase 2

Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History

Mild Cognitive ImpairmentAmnestic Mild Cognitive ImpairmentAmnestic Mild Cognitive Disorder+2 more
University of Texas Southwestern Medical Center75 enrolled1 locationNCT05446584
Recruiting
Not Applicable

Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline

Mild Traumatic Brain InjuryPost-Concussion Syndrome
University of Wisconsin, Madison55 enrolled1 locationNCT07044596
Recruiting
Not Applicable

Multidimensional Sleep Health Intervention to Optimize Concussion Recovery

TreatmentDepression, AnxietySleep Health+2 more
University of Colorado, Denver54 enrolled1 locationNCT07082218
Recruiting
Phase 2

Modulating Exercise Dosage to Improve Concussion Recovery

TreatmentDepression, AnxietyAerobic Exercise+2 more
University of Colorado, Denver216 enrolled3 locationsNCT05434130
Recruiting
Not Applicable

Acceptance and Commitment Therapy Integrated Vestibular Rehabilitation (ACTIVE) RCT

Mild traumatic brain injury (MTBI)Psychological healthConcussion, Mild+1 more
University of Pittsburgh250 enrolled2 locationsNCT06819904
Recruiting
Not Applicable

Combined Neuromodulation and Cognitive Training for Post-mTBI Depression

DepressionMild Traumatic Brain InjuryConcussion, Brain
University of California, San Diego72 enrolled1 locationNCT05682677
Recruiting
Not Applicable

Interest of an Attentional Evaluation by a Computerized Battery in the Management of Concussion in Young Rugby Players

Concussion, Brain
University Hospital, Clermont-Ferrand90 enrolled1 locationNCT05719844
Recruiting
Not Applicable

rTMS for Military TBI-related Depression

Depressive SymptomsConcussionMild Traumatic Brain Injury
Henry M. Jackson Foundation for the Advancement of Military Medicine198 enrolled3 locationsNCT05426967
Recruiting
Not Applicable

CORE (Cognitive Optimization Through Rehabilitation and Education) Study

Mild Traumatic Brain Injury, Concussion
University of Washington354 enrolled2 locationsNCT06859996
Recruiting
Not Applicable

Eye Recovery Automation for Post Injury Dysfunction (iRAPID)

convergence insufficiencyTraumatic Brain InjuryConcussion, Mild
New Jersey Institute of Technology100 enrolled1 locationNCT06105892