Concussion Clinical Trials

29 recruiting

Concussion Trials at a Glance

65 actively recruiting trials for concussion are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Not Applicable with 35 trials, with the heaviest enrollment activity in Pittsburgh, Calgary, and Philadelphia. Lead sponsors running concussion studies include University of Pittsburgh, Curtin University, and Children's Hospital of Philadelphia.

Browse concussion trials by phase

Treatments under study

About Concussion Clinical Trials

Looking for clinical trials for Concussion? There are currently 29 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Concussion trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Concussion clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 65 trials

Recruiting
Not Applicable

Combined Neuromodulation and Cognitive Training for Post-mTBI Depression

DepressionMild Traumatic Brain InjuryConcussion, Brain
University of California, San Diego72 enrolled1 locationNCT05682677
Recruiting
Not Applicable

Interest of an Attentional Evaluation by a Computerized Battery in the Management of Concussion in Young Rugby Players

Concussion, Brain
University Hospital, Clermont-Ferrand90 enrolled1 locationNCT05719844
Recruiting
Not Applicable

rTMS for Military TBI-related Depression

Depressive SymptomsConcussionMild Traumatic Brain Injury
Henry M. Jackson Foundation for the Advancement of Military Medicine198 enrolled3 locationsNCT05426967
Recruiting
Not Applicable

Symptom Exacerbation Following Mental Imagery in Patients With Persistent Post-Concussive Symptoms

Mild Traumatic Brain Injury, ConcussionPost Concussive Syndrome, Chronic
Reuth Rehabilitation Hospital60 enrolled1 locationNCT07166536
Recruiting
Not Applicable

Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)

COVID-19Post-Concussion SyndromeCOVID Long-Haul
Children's Hospital of Orange County125 enrolled1 locationNCT04978571
Recruiting
Not Applicable

Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms

Mild Traumatic Brain InjuryPersistent Post Concussion Syndrome
University of Minnesota30 enrolled1 locationNCT07246993
Recruiting
Not Applicable

Advancement of Vestibular Intervention Via Portable Electrical Stimulator (VIPES)

Mild Traumatic Brain Injury, Concussion
Vivonics, Inc.32 enrolled1 locationNCT07466589
Recruiting
Not Applicable

Concussion Treatment in Older Adults

Concussion, Mild
University of Pittsburgh50 enrolled1 locationNCT05849064
Recruiting
Not Applicable

Cervical Spine Focused Treatment for Patients With Persistent Concussion Symptoms and Neck Pain

Neck PainBrain Concussion
University of Pittsburgh40 enrolled4 locationsNCT06616272
Recruiting
Not Applicable

A Pragmatic Rehabilitation Intervention: The Active Rehab Study

Concussion, Brain
University of North Carolina, Chapel Hill130 enrolled2 locationsNCT05320822
Recruiting
Phase 2

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

DepressionAnxietyDysautonomia+8 more
University of California, Los Angeles75 enrolled1 locationNCT06073886
Recruiting
Not Applicable

Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury

Cognitive ImpairmentMotor DisordersMild Traumatic Brain Injury+1 more
State University of New York at Buffalo10 enrolled1 locationNCT05762796
Recruiting

Rapid, Accurate, Cost-effective Assessment of Blood Biomarkers for Diagnosis of Concussion

Concussion, Mild
University of Calgary225 enrolled1 locationNCT05588115
Recruiting
Not Applicable

Rehabilitation in Post Concussion Syndrome

Post-Concussion Syndrome
Rigshospitalet, Denmark70 enrolled1 locationNCT05785000
Recruiting
Not Applicable

Exercise Reset for Concussion in a Military Environment

Brain Concussion
State University of New York at Buffalo168 enrolled2 locationsNCT05498038
Recruiting
Phase 1

Treatment of Persisting Symptoms After Concussion With Psilocybin Assisted Therapy

Persisting Symptoms After Concussion
University of Calgary40 enrolled1 locationNCT06615908
Recruiting
Not Applicable

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

InsomniaTraumatic Brain InjuryDepression+7 more
Johns Hopkins University360 enrolled5 locationsNCT05663034
Recruiting
Not Applicable

Concussion Recovery and Support Program

Mild Traumatic Brain InjuryHeadacheBrain Concussion
Seattle Children's Hospital40 enrolled2 locationsNCT07097792
Recruiting
Not Applicable

Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

Brain TraumaNeurocognitive DysfunctionMild Cognitive Impairment+8 more
United States Naval Medical Center, San Diego160 enrolled2 locationsNCT06413173
Recruiting

Utilizing Electronic Clinical Decision Support to Enhance mTBI Care at the Primary Care Point of Entry

Mild Traumatic Brain InjuryBrain Concussion
Children's Hospital of Philadelphia3,000 enrolled1 locationNCT06693778