Mild Traumatic Brain Injury Clinical Trials

47 recruiting

Mild Traumatic Brain Injury Trials at a Glance

41 actively recruiting trials for mild traumatic brain injury are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 26 trials, with the heaviest enrollment activity in Minneapolis, Philadelphia, and San Antonio. Lead sponsors running mild traumatic brain injury studies include VA Office of Research and Development, Henry M. Jackson Foundation for the Advancement of Military Medicine, and Children's Hospital of Philadelphia.

Browse mild traumatic brain injury trials by phase

Treatments under study

About Mild Traumatic Brain Injury Clinical Trials

Looking for clinical trials for Mild Traumatic Brain Injury? There are currently 47 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Mild Traumatic Brain Injury trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Mild Traumatic Brain Injury clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 41 trials

Recruiting
Not Applicable

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

SleepMild Traumatic Brain InjurySleep Architecture+1 more
University of Missouri-Columbia15 enrolled1 locationNCT07385105
Recruiting
Not Applicable

Combined Neuromodulation and Cognitive Training for Post-mTBI Depression

DepressionMild Traumatic Brain InjuryConcussion, Brain
University of California, San Diego72 enrolled1 locationNCT05682677
Recruiting
Not Applicable

rTMS for Military TBI-related Depression

Depressive SymptomsConcussionMild Traumatic Brain Injury
Henry M. Jackson Foundation for the Advancement of Military Medicine198 enrolled3 locationsNCT05426967
Recruiting
Not Applicable

Improving Cognitive Rehabilitation Outcomes

Mild Traumatic Brain InjuryPosttraumatic Stress Disorder
VA Office of Research and Development144 enrolled2 locationsNCT07055633
Recruiting
Not Applicable

Symptom Exacerbation Following Mental Imagery in Patients With Persistent Post-Concussive Symptoms

Mild Traumatic Brain Injury, ConcussionPost Concussive Syndrome, Chronic
Reuth Rehabilitation Hospital60 enrolled1 locationNCT07166536
Recruiting
Phase 1

Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury

ImpulsivitySuicidal IdeationMild Traumatic Brain Injury
VA Office of Research and Development55 enrolled1 locationNCT05647044
Recruiting
Phase 3

Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)

Mild Traumatic Brain InjuryAdult Growth Hormone Deficiency
VA Office of Research and Development172 enrolled4 locationsNCT04867317
Recruiting
Not Applicable

TES HT100 Clinical Validation for Brain Injury Screening in Patients With Mild Head Trauma or Neurological Symptoms

Intracranial LesionsMild Traumatic Brain InjuryNeurological Symptoms Not Related to Head Trauma
B&B srl850 enrolled1 locationNCT07490418
Recruiting
Not Applicable

Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms

Mild Traumatic Brain InjuryPersistent Post Concussion Syndrome
University of Minnesota30 enrolled1 locationNCT07246993
Recruiting
Not Applicable

Advancement of Vestibular Intervention Via Portable Electrical Stimulator (VIPES)

Mild Traumatic Brain Injury, Concussion
Vivonics, Inc.32 enrolled1 locationNCT07466589
Recruiting
Phase 2

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

DepressionAnxietyDysautonomia+8 more
University of California, Los Angeles75 enrolled1 locationNCT06073886
Recruiting
Not Applicable

Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline

Mild Traumatic Brain Injury
University of Wisconsin, Madison55 enrolled1 locationNCT07044596
Recruiting
Not Applicable

Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury

Cognitive ImpairmentMotor DisordersMild Traumatic Brain Injury+1 more
State University of New York at Buffalo10 enrolled1 locationNCT05762796
Recruiting
Not Applicable

Passive Neurosensory Reintegration Training as a Tool to Augment Mild Traumatic Brain Injury

Mild Traumatic Brain Injury
University of Miami80 enrolled1 locationNCT07356167
Recruiting
Not Applicable

Behavioral Insomnia Treatment in Mild Traumatic Brain Injury

InsomniaMild Traumatic Brain Injury
The University of Texas Health Science Center at San Antonio160 enrolled1 locationNCT06551987
Recruiting
Not Applicable

Vestibular Rehabilitation App for Adults With Dizziness Related to mTBI

Mild Traumatic Brain InjuryDizziness
Mountain Home Research & Education Corporation68 enrolled3 locationsNCT06222450
Recruiting
Not Applicable

Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury

Mild Traumatic Brain InjuryPhotophobia
VA Office of Research and Development36 enrolled1 locationNCT06109909
Recruiting

Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders

MTBI - Mild Traumatic Brain Injury
Salus University150 enrolled1 locationNCT07282691
Recruiting
Not Applicable

Auditory Plasticity Training

Mild Traumatic Brain Injury
The University of Texas Health Science Center at San Antonio80 enrolled1 locationNCT06628505
Recruiting
Not Applicable

Concussion Recovery and Support Program

Mild Traumatic Brain InjuryHeadacheBrain Concussion
Seattle Children's Hospital40 enrolled2 locationsNCT07097792