Phase 3 Constipation Clinical Trials

8 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 18 of 8 trials

Recruiting
Phase 2Phase 3

Maralixibat in Patients With Cystic Fibrosis and Constipation

Cystic FibrosisConstipation Chronic Idiopathic
Children's Hospital Los Angeles20 enrolled1 locationNCT06413368
Recruiting
Phase 3

Assessing Tenapanor as a Treatment of CF-related Constipation.

ConstipationCystic Fibrosis
Massachusetts General Hospital25 enrolled1 locationNCT06810167
Recruiting
Phase 3

A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

Chronic Idiopathic Constipation (CIC)
Ardelyx692 enrolled79 locationsNCT07382167
Recruiting
Phase 3

Study to Assess Safety and Efficacy of Tenapanor for Treatment of IBS-C in Pediatric Patients 12 to Less Than 18 Years

Irritable Bowel Syndrome With Constipation (IBS-C)
Ardelyx180 enrolled41 locationsNCT05643534
Recruiting
Phase 3

Efficacy of Conservative Treatment of Functional Defecatory Disorders in Females With Pelvic Organ Prolapse

Functional ConstipationRectocelePelvic Floor Prolapse
Federal State Budgetary Scientific Institution "Federal Research Centre of Nutrition, Biotechnology100 enrolled2 locationsNCT04547816
Completed
Phase 3

A Randomised, Double-blinded, Placebo-controlled Study of Kivia (Trademark) 575mg Zyactinase (Registered Trademark) Capsule for the Improvement of Digestive Health Parameters in Subjects with Irritable Bowel Syndrome with Constipation Symptoms

Constipation dominant Irritable Bowel Syndrome (IBS-C)
Vital Food Processors Ltd180 enrolled10 locationsACTRN12613001222730
Completed
Phase 2Phase 3

Clinical and physiological evaluation of a Chinese herbal medicine for constipation-predominant Irritable Bowel Syndrome (C-IBS Trial).

Constipation-predominant Irritable Bowel Syndrome
University of Western Sydney160 enrolled1 locationACTRN12609000558224
Active
Phase 3

A 12 week prospective study of efficacy and acceptability of magnesium sulfate once weekly in adults as a management regime for constipation.

Constipation
Colocap Pharmaceuticals Pty Ltd100 enrolled1 locationACTRN12609000081213