Phase 2 Constipation Clinical Trials

14 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 114 of 14 trials

Recruiting
Phase 2

4-Week, Multi-center Dose-Ranging Study for the IBS-C in Pts. 6 to <12 Yrs

Irritable Bowel Syndrome With Constipation (IBS-C)
Ardelyx72 enrolled20 locationsNCT06553547
Recruiting
Phase 2

A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)

ConstipationIrritable Bowel Syndrome
Eli Lilly and Company342 enrolled1 locationNCT07545772
Recruiting
Phase 1Phase 2

Safety and Pharmacokinetics Study of Naldemedine in Paediatric Participants Receiving Opioids

Opioid-Induced Constipation (OIC)
Shionogi24 enrolled16 locationsNCT05588323
Recruiting
Phase 2Phase 3

Maralixibat in Patients With Cystic Fibrosis and Constipation

Cystic FibrosisConstipation Chronic Idiopathic
Children's Hospital Los Angeles20 enrolled1 locationNCT06413368
Recruiting
Phase 2

Pyridostigmine for the Treatment of Constipation in Parkinson Disease

ConstipationParkinson Disease
University of Vermont Medical Center16 enrolled1 locationNCT05603715
Recruiting
Phase 2Phase 3

Home Transcutaneous Electrical Acustimulation (TEA)

Irritable bowel syndrome with constipation
University of Michigan160 enrolled1 locationNCT05519683
Recruiting
Phase 2

A Study of Microbiome Transplantation for the Treatment of Constipation and/or Significant Bloating in Patients With Systemic Sclerosis

Constipationbloating
The University of Texas Health Science Center, Houston21 enrolled1 locationNCT06827977
Recruiting
Phase 1Phase 2

Anorectal Manometery in Pediatric Chronic Refractory Constipation

Chronic Constipation
Ain Shams University60 enrolled1 locationNCT06543979
Not Yet Recruiting
Phase 2

A clinical trial of a prebiotic powder for symptoms of Parkinson’s disease

Parkinson's disease (constipation and cognitive decline)
University of Newcastle180 enrolled2 locationsACTRN12623001186640
Recruiting
Phase 1Phase 2

Washed Microbiota Transplantation for Chronic Constipation in Adults

Constipation
The Second Hospital of Nanjing Medical University18 enrolled2 locationsNCT06106685
Terminated
Phase 2

Non-invasive medical device for the treatment of chronic constipation: 1. Proof of Principle study in children.

Chronic Constipation
GI therapies Pty Ltd40 enrolled1 locationACTRN12616001643460
Recruiting
Phase 2

A pilot study to explore the safety of pyridostigmine in constipated palliative care patients

ConstipationPalliative Care
Calvary Mater Newcastle10 enrolled2 locationsACTRN12614000540617
Completed
Phase 2Phase 3

Clinical and physiological evaluation of a Chinese herbal medicine for constipation-predominant Irritable Bowel Syndrome (C-IBS Trial).

Constipation-predominant Irritable Bowel Syndrome
University of Western Sydney160 enrolled1 locationACTRN12609000558224
Completed
Phase 2

A study comparing oxycodone to oxycodone/naloxone in moderate to severe, chronic cancer pain.

Moderate to severe chronic cancer pain. Constipation.
Mundipharma Research GmbH & Co KG180 enrolled8 locationsACTRN12607000493448