Corneal Dystrophy Clinical Trials

14 recruitingLast updated: June 18, 2026

There are 14 actively recruiting corneal dystrophy clinical trials across 9 countries. Studies span Not Applicable, Phase 2. Top locations include Barcelona, Barcelona, Spain, Bethesda, Maryland, United States, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Corneal Dystrophy Trials at a Glance

14 actively recruiting trials for corneal dystrophy are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Barcelona, Bethesda, and Boston. Lead sponsors running corneal dystrophy studies include Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Centre Hospitalier Régional Metz-Thionville, and CHU de Reims.

Browse corneal dystrophy trials by phase

Treatments under study

About Corneal Dystrophy Clinical Trials

Looking for clinical trials for Corneal Dystrophy? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Corneal Dystrophy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Corneal Dystrophy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 114 of 14 trials

Recruiting

National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark)), Stage 3 - Expansion of DNA and Data Repositories for Rare Inherited Ophthalmic Diseases

AniridiaAlbinismCorneal Dystrophy+4 more
National Eye Institute (NEI)1,000 enrolled2 locationsNCT06491615
Recruiting
Not Applicable

Effect of Descemet Membrane Polishing in Fuchs Endothelial Corneal Dystrophy

Fuchs' Endothelial Corneal Dystrophy
Centre Hospitalier Universitaire de Saint Etienne20 enrolled5 locationsNCT07539012
Recruiting
Not Applicable

Influence of Supine Positioning on the Outcomes After Descemet Membrane Endothelial Keratoplasty (DMEK)

Descemet Membrane Endothelial Keratoplasty (DMEK)Fuchs' Endothelial Corneal Dystrophy
University Hospital Heidelberg102 enrolled1 locationNCT07373821
Recruiting
Phase 2

DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy

Fuchs' Endothelial Corneal DystrophyFuchs
Design Therapeutics, Inc.28 enrolled2 locationsNCT07024693
Recruiting

SUCCESS Score Validation in Fuchs Dystrophy

Fuchs' Endothelial Corneal Dystrophy
Instituto Ramón y Cajal de Investigación Sanitaria250 enrolled1 locationNCT07265388
Recruiting
Not Applicable

High Resolution, High-speed Multimodal Ophthalmic Imaging

HypertensionStrokeDiabetes+12 more
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts1,200 enrolled1 locationNCT04129021
Recruiting
Phase 2

Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy

Fuchs' Endothelial Corneal Dystrophy
Massachusetts Eye and Ear Infirmary45 enrolled1 locationNCT04440280
Recruiting

OCT in Diagnosis of Irregular Corneas

Corneal DystrophyKeratoconusCorneal Opacity
Oregon Health and Science University445 enrolled1 locationNCT03504800
Recruiting
Not Applicable

Microsurgical Robot-assisted Corneal Transplant

Corneal Dystrophy
CHU de Reims10 enrolled1 locationNCT06844123
Recruiting

Comparison of Outcomes Between Femtosecond Laser-Assisted and Conventional Phacoemulsification in Fuchs Endothelial Corneal Dystrophy Patients With Cataracts

CataractFuchs' Endothelial Corneal Dystrophy
Eye & ENT Hospital of Fudan University120 enrolled1 locationNCT06966167
Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Multiple Endocrine Neoplasia Type 1Multiple Endocrine Neoplasia Type 2Rare Disorders+337 more
Sanford Health20,000 enrolled2 locationsNCT01793168
Recruiting

FECD-TRACE: Fuchs' Endothelial Corneal Dystrophy TRAjectory and Correlation With Genotype in the United Kingdom

Corneal DystrophyFuchs' Endothelial DystrophyFuchs Dystrophy+2 more
University College, London500 enrolled1 locationNCT06881771
Recruiting

Prognosis of Posterior Lamellar Keratoplasty, an Observational Cohort Study

Pseudophakic Bullous KeratopathyFuchs' Endothelial Corneal Dystrophy
Centre Hospitalier Régional Metz-Thionville1,000 enrolled1 locationNCT06859411
Recruiting
Not Applicable

Trial Comparing Cataract Surgery With Triple-DMEK in Patients With Cataract and Fuchs Endothelial Corneal Dystrophy

Cataract SurgeryCataract and Fuchs Endothelial Corneal Dystrophy
University of Cologne120 enrolled4 locationsNCT06425666