Coronary Syndrome Clinical Trials

188 recruitingLast updated: May 13, 2026

There are 188 actively recruiting coronary syndrome clinical trials across 48 countries. Studies span Not Applicable, Phase 4, Phase 3, Phase 2, Early Phase 1. Top locations include Beijing, Beijing Municipality, China, Seoul, South Korea, Jinan, Shandong, China. Updated daily from ClinicalTrials.gov.


Coronary Syndrome Trials at a Glance

188 actively recruiting trials for coronary syndrome are listed on ClinicalTrialsFinder across 6 cities in 48 countries. The largest study group is Not Applicable with 59 trials, with the heaviest enrollment activity in Beijing, Seoul, and Jinan. Lead sponsors running coronary syndrome studies include Qilu Hospital of Shandong University, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), and Federico II University.

Browse coronary syndrome trials by phase

Treatments under study

About Coronary Syndrome Clinical Trials

Looking for clinical trials for Coronary Syndrome? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Coronary Syndrome trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Coronary Syndrome clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 188 trials

Recruiting

Florbetaben for Imaging of Vascular Amyloid

StrokeAcute Coronary SyndromeTransient Ischemic Attack+1 more
Ottawa Heart Institute Research Corporation30 enrolled1 locationNCT06091319
Recruiting
Not Applicable

A Clinical Study on the Effect of Cardiopulmonary Function and Quality of Life in Patients With Acute Coronary Syndrome Complicated by Heart Failure by "Lying-Sitting-Standing" Sequential Baduanjin

ACS (Acute Coronary Syndrome)HF - Heart Failure
Xiling Qi65 enrolled1 locationNCT07486791
Recruiting
Not Applicable

Ticino Artificial InTelligence integrAtioN for Occlusion Myocardial Infarction

Myocardial Infarction (MI)Acute Coronary Syndrome (ACS)
Cardiocentro Ticino500 enrolled1 locationNCT07077057
Recruiting
Not Applicable

Leave Nothing Behind Study Which Compares DCB With Bail Out BRS Versus BRS Strategy Alone

Percutaneous Coronary Intervention (PCI)Acute Coronary Syndrome (ACS)Drug-coated Balloon+1 more
Ceric Sàrl2,256 enrolled1 locationNCT07038408
Recruiting
Not Applicable

Orbital Atherectomy vs Intravascular Lithotripsy for the Treatment of Calcified Coronary Nodules (ORBIT-SHOCK).

Chronic Coronary SyndromeCoronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)+6 more
Spanish Society of Cardiology50 enrolled6 locationsNCT06736665
Recruiting
Phase 4

Effect of ZaStaprazan on Platelet Reactivity of Clopidogrel After PercuTaneous CoronAry InteRvention

Chronic Coronary Syndrome
Yonsei University100 enrolled1 locationNCT07471867
Recruiting
Phase 3

Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes

Acute Coronary Syndrome
Novartis Pharmaceuticals300 enrolled58 locationsNCT07102628
Recruiting
Not Applicable

Artificial Intelligence-Driven Medipixel Fractional Flow Reserve Versus Invasive Fractional Flow Reserve-Guided PCI Trial (AIM-FFR Trial)

Acute Coronary SyndromeCoronary Artery DiseaseChronic Coronary Syndrome
Samsung Medical Center2,100 enrolled23 locationsNCT07329699
Recruiting

Artificial Intelligence Based Timing, Infarct Size and Outcomes in Acute Coronary Occlusion Myocardial Infarction

Coronary Arterial Disease (CAD)Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
Azienda Ospedaliera di Bolzano1,500 enrolled1 locationNCT06910436
Recruiting
Not Applicable

TeleheartCR vs. Clinic-Based Cardiac Rehabilitation After Acute Coronary Syndrome

Myocardial InfarctionAcute Coronary Syndrome (ACS)
Columbia University250 enrolled1 locationNCT07541014
Recruiting
Not Applicable

Positive Emotions Following Acute Cardiac Events

Physical InactivityAcute Coronary Syndrome
Massachusetts General Hospital280 enrolled1 locationNCT05412862
Recruiting
Phase 4

Multicenter Trial of Antithrombotic Strategies in Acute Coronary Syndrome With Coronary Artery Ectasia

Coronary Artery EctasiaSTEMI - ST Elevation Myocardial InfarctionNSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI)+1 more
Instituto Nacional de Cardiologia Ignacio Chavez326 enrolled1 locationNCT07511257
Recruiting
Not Applicable

IVUS-Guided vs Angiography-Guided PCI in Acute Coronary Syndrome

acute coronary syndromes (ACS)
SUK MIN SEO1,500 enrolled1 locationNCT07512778
Recruiting
Not Applicable

Fexuprazan for Prevention of Upper Gastrointestinal Bleeding in High Bleeding Risk Patients Receiving Dual Antiplatelet Therapy

Coronary Artery Disease (CAD)acute coronary syndromes (ACS)
SUK MIN SEO400 enrolled1 locationNCT07479056
Recruiting
Not Applicable

A Study Evaluating the Vascular Healing and Neointimal Transformation at 1 Month After Implantation of BioFreedom™ Drug-coated Stents and the Xience Drug-eluting Stent System in Patients With Acute Coronary Syndrome and High Bleeding Risk Using Optical Coherence Tomography

Coronary Heart DiseaseAcute Coronary Syndrome
China National Center for Cardiovascular Diseases60 enrolled1 locationNCT07230847
Recruiting

Prospective Multicenter Registry of Gender, Diversity and Inclusion (GEDI) of Women With Acute Coronary Syndrome

Acute Coronary SyndromeGenetic PredispositionGender
IRCCS San Raffaele100 enrolled4 locationsNCT06441942
Recruiting
Phase 4

Effect of Intravenous Iron on Quality of Life in Older Patients With Acute Coronary Syndrome

Elderly (People Aged 65 or More)Iron Deficienciesacute coronary syndromes (ACS)
Fundación para la Investigación del Hospital Clínico de Valencia538 enrolled9 locationsNCT07476859
Recruiting
Not Applicable

Point-of-Care Troponin Testing in the Emergency Department

Acute Coronary Syndromes
KU Leuven1,552 enrolled1 locationNCT06845826
Recruiting

A Prospective, Single-center, Observational Study Aiming to Assess the Predictive Role of Flow Mediated Dilatation in Acute Coronary Syndromes, Combined With Echocardiographic and Biochemical Indices

Endothelial Function (FMD)Acute Coronary SyndromesFlow Mediated Dilation
Aristotle University Of Thessaloniki100 enrolled1 locationNCT06890013
Recruiting
Early Phase 1

Placebo-controlled Study of Single and Multiple Ascending Doses of UDP-003 in Healthy Human Participants and Patients

Atherosclerotic Cardiovascular DiseaseAcute Coronary Syndromes
Cyclarity Therapeutics, Inc.84 enrolled1 locationNCT06813339