Phase 2 COVID-19 Clinical Trials

42 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 42 trials

Recruiting
Phase 2

Arginine Replacement Therapy in COVID-19

COVID-19
Emory University21 enrolled1 locationNCT05855330
Recruiting
Phase 1Phase 2

Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia

Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmCOVID-19 Infection+2 more
M.D. Anderson Cancer Center70 enrolled1 locationNCT04565665
Recruiting
Phase 2

Study to Evaluate the Efficacy and Safety of Plitidepsin in Adults With Post-COVID-19 Condition (PCC)

Post COVID-19 ConditionLong COVIDLong COVID Syndrome+2 more
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia90 enrolled1 locationNCT06766825
Recruiting
Phase 2

Mitoquinone/Mitoquinol Mesylate as Oral and Safe Postexposure Prophylaxis for Covid-19

COVID-19SARS-CoV Infection
University of Texas Southwestern Medical Center112 enrolled1 locationNCT05886816
Recruiting
Phase 2

A Vaccine Booster (GEO-CM04S1) for the Prevention of COVID-19 in Patients With Chronic Lymphocytic Leukemia

Chronic Lymphocytic LeukemiaCOVID-19 Infection
City of Hope Medical Center80 enrolled1 locationNCT05672355
Recruiting
Phase 2

Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia.

PneumoniaRespiratory InfectionAcute Respiratory Distress Syndrome+3 more
Vasomune Therapeutics, Inc.120 enrolled5 locationsNCT05123755
Recruiting
Phase 2

OPtimisation of Antiviral Therapy in Immunocompromised COVID-19 Patients: a Randomized Factorial Controlled Strategy Trial

COVID-19Immunodeficiency
ANRS, Emerging Infectious Diseases256 enrolled18 locationsNCT05587894
Recruiting
Phase 2

Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)

COVID-19
University of Oxford3,800 enrolled7 locationsNCT05041907
Recruiting
Phase 2

OPtimisation of Antiviral Therapy in Immunocompromised COVID-19 Patients

COVID-19Immunodeficiency
Calmy Alexandra256 enrolled4 locationsNCT07406217
Recruiting
Phase 2

A Trial of a Next Generation COVID-19 Vaccine Delivered by Inhaled Aerosol

COVID-19 Infection
McMaster University350 enrolled2 locationsNCT06381739
Recruiting
Phase 2

Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS

Post-Acute COVID-19 SyndromePostural Tachycardia Syndrome (POTS)
Vanderbilt University Medical Center50 enrolled1 locationNCT07189936
Recruiting
Phase 2Phase 3

Safety and Efficacy of Anakinra Treatment for Patients With Post Acute Covid Syndrome

Post-Acute COVID-19 SyndromeLong COVIDPost-Acute COVID-19
Hellenic Institute for the Study of Sepsis182 enrolled24 locationsNCT05926505
Recruiting
Phase 2

Immunoadsorption in Autoimmune Long COVID

Long COVID-19 SyndromeLong COVIDLong COVID Syndrome
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)70 enrolled1 locationNCT07316127
Recruiting
Phase 2

A Nasal Treatment for COVID-19

HealthyCOVID-19
Indiana University40 enrolled1 locationNCT05799521
Recruiting
Phase 2

Safety and Tolerability of a Newcastle Disease Virus-Based Mucosal COVID-19 Vaccine in Previously Vaccinated Adults

COVID-19
CastleVax Inc.200 enrolled2 locationsNCT07215520
Recruiting
Phase 1Phase 2

A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses

COVID-19
Kara Chew80 enrolled2 locationsNCT06810934
Recruiting
Phase 2

Magnetic Resonance Analysis of Neural Inflammatory Factors and External Stimulation

Long COVID-19 SyndromeLong COVIDLong COVID Syndrome+2 more
University of New Mexico60 enrolled1 locationNCT06940609
Recruiting
Phase 1Phase 2

Safety and Immunogenicity of a Sub-unit Protein CD40.RBDv Bivalent COVID-19 Vaccine, Adjuvanted or Not, as a Booster in Volunteers.

COVID-19
ANRS, Emerging Infectious Diseases215 enrolled2 locationsNCT06255626
Recruiting
Phase 2Phase 3

A Study of Apabetalone in Subjects With Long -COVID

Post-Acute COVID-19 Syndrome
Resverlogix Corp200 enrolled3 locationsNCT06590324
Recruiting
Phase 2Phase 3

Multicenter Randomized Double-blind Placebo-controlled Study to Investigate Azvudine in Symptomatic Adults With COVID-19 at Increased Risk of Progressing to Severe Illness

COVID-19 Respiratory Infection
Peking Union Medical College Hospital1,096 enrolled1 locationNCT05689034