Phase 3 COVID-19 Clinical Trials
28 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 28 trials
Recruiting
Phase 3
A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
COVID-19 (SARS-CoV-2) infection
Pfizer2,330 enrolled246 locationsNCT06679140
Recruiting
Phase 3
A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
COVID-19 Infection
Pfizer300 enrolled147 locationsNCT07013474
Recruiting
Phase 3
Safety and Serum Virus Neutralizing Antibody Responses of VYD2311, a COVID-19 Vaccine, and Coadministered VYD2311 With a COVID-19 Vaccine
COVID-19
Invivyd, Inc.210 enrolled1 locationNCT07655180
Recruiting
Phase 3
A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)
Coronavirus Disease (COVID-19)
Merck Sharp & Dohme LLC3,082 enrolled224 locationsNCT06667700
Recruiting
Phase 3
sElective Serotonin reuPtake inhibitoRs In posT-covid After COVID-19
Post COVID-19Post-COVID ConditionsPost-COVID
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)160 enrolled1 locationNCT07359482
Recruiting
Phase 3
Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study
COVID-19Lower Respiratory Tract InfectionImmunocompromised+1 more
Ansun Biopharma, Inc.274 enrolled67 locationsNCT03808922
Recruiting
Phase 3
Study of VYD2311 for the Prevention of COVID-19
COVID-19
Invivyd, Inc.1,770 enrolled20 locationsNCT07298434
Recruiting
Phase 3
Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID
SARS-CoV-2 infectionCOVID-19Long COVID+1 more
Wes Ely550 enrolled17 locationsNCT06631287
Recruiting
Phase 3
Immunosuppression and COVID-19 Boosters
COVID-19
Kirby Institute320 enrolled5 locationsNCT05415267
Recruiting
Phase 2Phase 3
Safety and Efficacy of Anakinra Treatment for Patients With Post Acute Covid Syndrome
Post-Acute COVID-19 SyndromeLong COVIDPost-Acute COVID-19
Hellenic Institute for the Study of Sepsis182 enrolled24 locationsNCT05926505
Recruiting
Phase 3
A Study to Learn About a COVID-19 Vaccine in Healthy Adults 50 Through 64 Years of Age
COVID-19
BioNTech SE25,500 enrolled208 locationsNCT07300839
Recruiting
Phase 3
EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease
COVID-19
Pfizer160 enrolled73 locationsNCT05261139
Recruiting
Phase 2Phase 3
A Study of Apabetalone in Subjects With Long -COVID
Post-Acute COVID-19 Syndrome
Resverlogix Corp200 enrolled3 locationsNCT06590324
Recruiting
Phase 2Phase 3
Multicenter Randomized Double-blind Placebo-controlled Study to Investigate Azvudine in Symptomatic Adults With COVID-19 at Increased Risk of Progressing to Severe Illness
COVID-19 Respiratory Infection
Peking Union Medical College Hospital1,096 enrolled1 locationNCT05689034
Recruiting
Phase 3
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
Community-acquired Pneumonia, Influenza, COVID-19
UMC Utrecht20,000 enrolled408 locationsNCT02735707
Recruiting
Phase 3Phase 4
Intramuscular versus Subcutaneous COVID-19 needle length RCT
COVID-19
Medical Research Institute of New Zealand (MRINZ)400 enrolled1 locationACTRN12624000294550
Recruiting
Phase 2Phase 3
Phase 2/Phase 3 Study To Evaluate The Efficacy And Safety Of Ramatroban Along With The Standard Of Care In Subjects Hospitalized For COVID Pneumonia
COVID-19 pneumoniaCOVID-19 Respiratory Infection
KARE Biosciences324 enrolled7 locationsNCT05706454
Completed
Phase 3
Ivermectin to prevent Coronavirus
COVID-19
Monash University1,000 enrolled1 locationACTRN12621001535864
Terminated
Phase 3
Impact of Colchicine To Improve long-COVID-19 or ARDS Outcomes
COVID-19 Respiratory Infection
University of Sydney1,000 enrolled2 locationsACTRN12621000637842
Not Yet Recruiting
Phase 3
A randomized double-blind placebo-controlled trial of oral ivermectin for outpatient treatment of those at high risk for hospitalization due to COVID-19
SARS-CoV-2 (COVID-19),
Neuroscience Trials Australia400 enrolled1 locationACTRN12620000982910