Phase 3 Critical Illness Clinical Trials

13 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 113 of 13 trials

Recruiting
Phase 2Phase 3

Azithromycin for Critical Asthma - Pediatrics

Critical IllnessPediatric Asthma
Johns Hopkins All Children's Hospital100 enrolled1 locationNCT06223828
Recruiting
Phase 3

The VITDALIZE Study: Effect of High-dose Vitamin D3 on 28-day Mortality in Adult Critically Ill Patients

Critical IllnessVitamin D Deficiency
Medical University of Graz2,400 enrolled18 locationsNCT03188796
Recruiting
Phase 3

Goal-Directed Sedation in Mechanically Ventilated Infants and Children

Post Traumatic Stress DisorderDeliriumCritical Illness+2 more
Vanderbilt University Medical Center372 enrolled1 locationNCT04801589
Recruiting
Phase 3

Hydrocortisone and Fludrocortisone for Critical Illness-related Corticosteroid Insufficiency

Critical Illness Related Corticosteroids Insufficiency
Assistance Publique - Hôpitaux de Paris1,092 enrolled1 locationNCT04404400
Recruiting
Phase 3

Preventing Cardiovascular Collapse With Vasopressors During Tracheal Intubation

Respiratory FailureCritical Illness
University of Turin, Italy420 enrolled6 locationsNCT05014581
Recruiting
Phase 2Phase 3

Muscle growth and anabolism in intensive care survivors

Intensive CareCritical illness nutrition
Sir Charles Gairdner Hospital60 enrolled3 locationsACTRN12623000729628
Recruiting
Phase 2Phase 3

ITHRIVE: Iron and erythropoietin use in anaemic patients in the intensive care

Critical IllnessAnaemia
Fiona Stanley Hospital550 enrolled9 locationsACTRN12621000595819
Recruiting
Phase 3

ErythroPOietin Alfa to Prevent Mortality and Reduce Severe Disability in Critically Ill TRAUMA Patients (EPO-TRAUMA)

Critical IllnessTrauma
Monash University2,500 enrolled25 locationsACTRN12619001632189
Completed
Phase 2Phase 3

Abdominal Functional Electrical Stimulation To Assist Ventilator Weaning In Critically Ill Patients

Traumatic Brain InjurySepsisStroke+1 more
Neuroscience Research Australia20 enrolled1 locationACTRN12617001180303
Withdrawn
Phase 2Phase 3

A randomised, double-blind, double-dummy study of the effects of insulin and glucagon-like peptide-1 on glycaemia, gastric emptying, gastro-oesophageal reflux and mesenteric blood flow in the critically ill

Gastric emptyingGlycaemic controlCritical Illness
Dr Yasmine Ali Abdelhamid50 enrolled1 locationACTRN12613001383752
Completed
Phase 3

0.9% saline vs. Plasma-Lyte 148 for Intensive Care Fluid Therapy. (the SPLIT study)

Intravenous Fluid Management in Critical Illness
Medical Research Institute of New Zealand2,500 enrolled1 locationACTRN12613001370796
Completed
Phase 3Phase 4

Australian and New Zealand Cluster Randomised trial of Evidence-based Guidelines for Nutrition Support in Critical Illness

Critical illness, fasting, starvation, malnourishment
Dr Gordon Doig1,500 enrolled1 locationACTRN12608000407392
Completed
Phase 3

Early PN trial

Critical Illness (ICU pts)
University of Sydney1,470 enrolled1 locationACTRN12605000704695