Phase 4 Critical Illness Clinical Trials
11 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–11 of 11 trials
Recruiting
Phase 4
Effect of Protocolized Magnesium Replacement on Mortality and Atrial Fibrillation in Critically Ill Patients
Critical Illness
Scarborough General Hospital3,253 enrolled6 locationsNCT07173855
Recruiting
Phase 4
CReep and Maintenance flUid Sodium Chloride ADministration rEduction in cRitically Ill adultS
Critical IllnessCritical Care, Intensive CareFluid and Electrolyte Imbalance+2 more
University Hospital, Antwerp640 enrolled4 locationsNCT07189091
Recruiting
Phase 4
Sedation Efficacy and Safety of Remazolam Besylate in Ventilated Surgical Critically Ill Patients
SurgeryMechanical Ventilation ComplicationCritical Illness+3 more
Beijing Shijitan Hospital, Capital Medical University306 enrolled1 locationNCT06575530
Recruiting
Phase 4
Magnesium Prophylaxis for the Prevention of New-Onset Atrial Fibrillation in Critically Ill Patients
Critical IllnessNew Onset Atrial Fibrillation
Dr. Stephanie Sibley200 enrolled4 locationsNCT05829317
Completed
Phase 4
Route of administration of magnesium replacement in the ICU
Critical IllnessHypomagnesemia
Royal Melbourne Hospital330 enrolled1 locationACTRN12623000248662
Completed
Phase 4
The effect of standard versus energy dense feeds on gastric emptying and glucose metabolism in critically ill patients
Critical Illness
Intensive Care Research Unit, Royal Adelaide Hospital25 enrolled1 locationACTRN12617000384358
Active
Phase 4
A single centre nested cohort study investigating the effect of using 0.9 % saline or Plasmalyte 148 as primary fluid therapy on gastrointestinal complications in mechanically ventilated patients with nasogastric enteral nutrition
Mechanical VentilationCritical Illness
Medical Research Institute of New Zealand200 enrolled1 locationACTRN12614000269639
Completed
Phase 4
The effect of routine pantoprazole administration when compared to placebo on gastrointestinal bleeding, ventilator-associated pneumonia and Clostridium difficile infection in enterally-fed mechanically ventilated critically ill patients: A prospective randomised study
Gastrointestinal BleedingCritical Illness
Dr Adam Deane500 enrolled1 locationACTRN12613000807752
Not Yet Recruiting
Phase 4
Proof-of-Concept Study of Insulin Glargine as Basal Insulin Support for Recovering Critically Ill Patients
stress diabetes in critical illness
Canterbury District Health Board/Christchurch Hospital60 enrolled1 locationACTRN12610000574044
Not Yet Recruiting
Phase 4
Synergistic effect of Clonidine on sedation requirements in Paediatric Intensive Care (PICU)
sedation in critical illness
Alana Kirkwood120 enrolled1 locationACTRN12610000079044
Completed
Phase 3Phase 4
Australian and New Zealand Cluster Randomised trial of Evidence-based Guidelines for Nutrition Support in Critical Illness
Critical illness, fasting, starvation, malnourishment
Dr Gordon Doig1,500 enrolled1 locationACTRN12608000407392