Phase 2 Critical Illness Clinical Trials
19 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–19 of 19 trials
Recruiting
Phase 1Phase 2
PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia
Critical IllnessBronchopulmonary Dysplasia (BPD)Premature Births
Duke University28 enrolled4 locationsNCT07101640
Recruiting
Phase 2
Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults
OsteoporosisCritical Illness
Australian and New Zealand Intensive Care Research Centre450 enrolled22 locationsNCT04608630
Recruiting
Phase 2
The "What Is Important to Us" Communication Intervention Pilot Clinical Trial
Neurologic DisorderCritical Illness
Seattle Children's Hospital160 enrolled1 locationNCT06208332
Recruiting
Phase 2Phase 3
Azithromycin for Critical Asthma - Pediatrics
Critical IllnessPediatric Asthma
Johns Hopkins All Children's Hospital100 enrolled1 locationNCT06223828
Recruiting
Phase 2
Response to frusemide in critically ill patients requiring dialysis
Critical IllnessAcute Renal Failure
St Vincent's Hospital, Melbourne40 enrolled2 locationsACTRN12625001227482
Recruiting
Phase 1Phase 2
Safety and Feasibility of a Self-Balancing Exoskeleton for Rehabilitation in the Thoracic Surgical Intensive Care Unit: a Pilot Trial
Critical Illness
Wandercraft5 enrolled1 locationNCT07220733
Recruiting
Phase 2
Use of Vasopressin in Patients at High Risk of Acute Kidney Injury Admitted to the ICU
Critical Illness
Hospital do Coracao60 enrolled1 locationNCT06547892
Not Yet Recruiting
Phase 2
Restoration of gut microbiota in Persistent Critical illness using Faecal Microbiota Transplantation (The ROCIT-FMT Trial): a pilot phase I/II trial
Persistent Critical Illness
South Metropolitan Health Service - Fiona Stanley Hospital40 enrolled1 locationACTRN12624000034538
Recruiting
Phase 2
Effects of Early Testosterone Gel Administration on Physical Performance in the Critically Ill
Critical Illness
University Hospital, Clermont-Ferrand600 enrolled5 locationsNCT05825092
Recruiting
Phase 2Phase 3
Muscle growth and anabolism in intensive care survivors
Intensive CareCritical illness nutrition
Sir Charles Gairdner Hospital60 enrolled3 locationsACTRN12623000729628
Recruiting
Phase 2Phase 3
ITHRIVE: Iron and erythropoietin use in anaemic patients in the intensive care
Critical IllnessAnaemia
Fiona Stanley Hospital550 enrolled9 locationsACTRN12621000595819
Completed
Phase 2
TARGET Protein Feasibility Study: a prospective, blinded, parallel group, randomised controlled trial to assess the feasibility of conducting a phase III trial of protein targets in critically ill adults
Critical Illness
Professor Marianne Chapman120 enrolled8 locationsACTRN12618001829202
Completed
Phase 2Phase 3
Abdominal Functional Electrical Stimulation To Assist Ventilator Weaning In Critically Ill Patients
Traumatic Brain InjurySepsisStroke+1 more
Neuroscience Research Australia20 enrolled1 locationACTRN12617001180303
Completed
Phase 2
The GAINS trial - Growth and Anabolism in Intensive Care Survivors
Intensive CareCritical illness malnutrition
Sir Charles Gairdner Hospital20 enrolled2 locationsACTRN12616000835448
Completed
Phase 2
A pilot, randomized, blinded, multi-centre, feasibility, safety and biochemical and physiological study of normal saline versus plasmalyte in intensive therapy
Critical Illness
Austin Hospital60 enrolled3 locationsACTRN12615000158561
Withdrawn
Phase 2Phase 3
A randomised, double-blind, double-dummy study of the effects of insulin and glucagon-like peptide-1 on glycaemia, gastric emptying, gastro-oesophageal reflux and mesenteric blood flow in the critically ill
Gastric emptyingGlycaemic controlCritical Illness
Dr Yasmine Ali Abdelhamid50 enrolled1 locationACTRN12613001383752
Active
Phase 2
Intravenous iRon or placebO for aNaeMiA in iNtensive care: The Ironman Randomised Controlled Trial
Anaemia in critical illness
Edward Litton140 enrolled4 locationsACTRN12612001249842
Recruiting
Phase 2
The Effect of Prolonged Glucagon-like Peptide 1 Infusion on Gastric Emptying in Healthy Volunteers
Critical Illness Induced HyperglycaemiaDiabetesHyperglycaemia
Mahesh Umapathysivam10 enrolled1 locationACTRN12612001035819
Not Yet Recruiting
Phase 2
Nephro-protective effects of L-amino acids in critically ill patients. A phase II multicentre randomised controlled trial.
Critical Illness Intensive Care Unit (ICU) Patients
National Health and Medical Research Council (NHMRC)474 enrolled1 locationACTRN12609001015235