Phase 2 Dependence Clinical Trials

16 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 116 of 16 trials

Recruiting
Phase 2

Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal

Chronic PainDrug Dependence of Morphine TypeSymptom, Withdrawal
University of Calgary40 enrolled1 locationNCT04939623
Recruiting
Phase 2

Cannabidiol for Reducing Cigarette Use

Tobacco Use DisorderTobacco DependenceTobacco Smoking
University of California, Los Angeles120 enrolled1 locationNCT06218056
Recruiting
Phase 2

Effects of Tirzepatide on Alcohol Intake in Patients Diagnosed With Schizophrenia and Alcohol Use Disorder

AlcoholismSchizophrenia DisordersAlcohol Use Disorder+2 more
Anders Fink-Jensen, MD, DMSci108 enrolled2 locationsNCT06939088
Recruiting
Phase 2Phase 3

Baclofen for Improving Benzodiazepine Titration in Benzodiazepine Dependence

Benzodiazepine Dependence
Hospices Civils de Lyon93 enrolled2 locationsNCT05935553
Recruiting
Phase 2

Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage

Opioid UseSubarachnoid Hemorrhage, AneurysmalHeadache+1 more
The University of Texas Medical Branch, Galveston15 enrolled1 locationNCT07294118
Recruiting
Phase 2

Ketamine and Neurofeedback as Combined Therapeutic Interventions to Target Glutamatergic Neurotransmission in Alcohol Use Disorder

AlcoholismAlcohol Use Disorder (AUD)Alcohol Abuse/Dependence
Dr. med. Marcus Herdener75 enrolled1 locationNCT06969937
Recruiting
Phase 2

Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication

Chronic PainOpioid Dependence
University of British Columbia10 enrolled1 locationNCT05585229
Recruiting
Phase 2

Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial

Alcohol Use DisorderAlcohol DependenceAlcohol Abuse
University of Iowa80 enrolled1 locationNCT06405607
Recruiting
Phase 1Phase 2

Overcoming Nicotine Dependence to Enable Quitting

Smoking CessationSmoking BehaviorsNicotine Dependence+2 more
Rush University Medical Center780 enrolled1 locationNCT05513872
Recruiting
Phase 2

Effects of Intranasal Oxytocin in the Treatment of Benzodiazepine Withdrawal: A Pilot RCT

Benzodiazepine Dependence
St. Olavs Hospital60 enrolled1 locationNCT06757517
Recruiting
Phase 2

Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction

Cocaine Use DisorderCocaine Dependence
Dr. med. Marcus Herdener120 enrolled1 locationNCT06125054
Recruiting
Phase 2

MDMA-assisted Prolonged Exposure Therapy for Comorbid Alcohol Use Disorder and Post-traumatic Stress Disorder

Alcohol Use DisorderPTSDAlcohol Dependence
University of Sydney120 enrolled2 locationsNCT05709353
Not Yet Recruiting
Phase 2

A Novel Opioid Treatment Program In Individuals With An Opioid Use Disorder

Opioid DependenceAddiction
Western Sydney Local Health District Drug Health45 enrolled1 locationACTRN12621000899842
Completed
Phase 2

Dose-escalating, phase 2 study of oral lisdexamfetamine in adults with methamphetamine dependence

Methamphetamine Dependence
St. Vincent's Hospital, Sydney20 enrolled2 locationsACTRN12615000391572
Completed
Phase 2

Clinical Study of New Intraocular Lens Design in Participants requiring Bilaterial Cataract Removal

Cataract extraction and artificial lens implantation for vision acuity restoration for far, intermediate and near vision with reduced need for further spectacle correction/dependence.
Abbott Medical Optics Inc50 enrolled1 locationACTRN12613000262707
Completed
Phase 2

A randomised double blind placebo controlled clinical trial of the efficacy of an Australian naltrexone implant compared to oral naltrexone for the long-term management of heroin-dependent persons

Heroin dependence
University of Western Australia70 enrolled1 locationACTRN12606000308594