Phase 2 Diabetes Clinical Trials

169 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 169 trials

Recruiting
Phase 2

Glucokinase Activator in Monogenic Diabetes

Diabetes MellitusMonogenic Diabetes
Chinese University of Hong Kong44 enrolled1 locationNCT06976658
Recruiting
Phase 2

Regulation of Endogenous Glucose Production by Central KATP Channels

Diabetes MellitusGlucose Metabolism Disorders
Albert Einstein College of Medicine100 enrolled1 locationNCT03540758
Recruiting
Phase 2

A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

Type 1 Diabetes Mellitus With Hypoglycemia
Zucara Therapeutics Inc.186 enrolled46 locationsNCT05762107
Recruiting
Phase 2Phase 3

Open-Label Study of Dimethyl Fumarate in Adults With Type 1 Diabetes

Type 1 Diabetes Mellitus
Nanjing Medical University96 enrolled1 locationNCT07548996
Recruiting
Phase 2

Sleep, Diabetic Retinopathy and Melatonin

Diabetes MellitusDiabetic Retinopathy
University of Illinois at Chicago42 enrolled1 locationNCT04547439
Recruiting
Phase 2

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

Type 2 DiabetesCortisol Excess
Sparrow Pharmaceuticals1,500 enrolled47 locationsNCT07296484
Recruiting
Phase 2

HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes

Type 2 Diabetes
Housey Healthcare ULC300 enrolled25 locationsNCT07546929
Recruiting
Phase 2

A Study of LY3938577 in Participants With Type 2 Diabetes Previously Treated With Basal Insulin

Diabetes Mellitus, Type 2
Eli Lilly and Company100 enrolled26 locationsNCT07215312
Recruiting
Phase 2

INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes

Type 1 Diabetes Mellitus
Mannkind Corporation100 enrolled10 locationsNCT07224321
Recruiting
Phase 2

A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus (T2DM)
Alnylam Pharmaceuticals40 enrolled1 locationNCT07465224
Recruiting
Phase 1Phase 2

A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled20 locationsNCT06845202
Recruiting
Phase 2

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

Type 2 Diabetes
Eli Lilly and Company240 enrolled61 locationsNCT06897475
Recruiting
Phase 2

TArgeting Type 1 Diabetes Using POLyamines (TADPOL)

Type 1 Diabetes
Emily K. Sims81 enrolled7 locationsNCT05594563
Recruiting
Phase 2

A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus

Type II Diabetes Mellitus
Corxel Pharmaceuticals240 enrolled46 locationsNCT07340320
Recruiting
Phase 2

Metformin for People With CFRD on CFTR Modulator Therapy to Improve Ion Channel Function

Cystic FibrosisCystic Fibrosis-related Diabetes
University of Kansas Medical Center30 enrolled1 locationNCT04530383
Recruiting
Phase 2

NAD Augmentation in Diabetes Kidney Disease

Type2diabetesDiabetic Kidney Disease
Brigham and Women's Hospital156 enrolled1 locationNCT05759468
Recruiting
Phase 2

Efficacy and Safety of Teplizumab in Japanese Participants With Stage 2 Type 1 Diabetes

Type 1 Diabetes Mellitus
Sanofi10 enrolled11 locationsNCT06791291
Recruiting
Phase 2

An Adaptive Design Study of MTX228

Type 1 Diabetes Mellitus
University of Alberta24 enrolled1 locationNCT06474598
Recruiting
Phase 2

Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets

Type 2 Diabetes
Biomea Fusion Inc.60 enrolled15 locationsNCT07502495
Recruiting
Phase 1Phase 2

A First-In-Human Study of ARO-ALK7 in Adults With Obesity With and Without Type 2 Diabetes Mellitus

ObesityDiabetes Mellitus, Type 2
Arrowhead Pharmaceuticals138 enrolled8 locationsNCT06937203