Early Phase 1 Diabetes Clinical Trials
27 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 27 trials
Recruiting
Early Phase 1
Autologous CD6-CAR Treg Cells for Patients With Stage 3 Type 1 Diabetes
Stage 3 Type 1 Diabetes
City of Hope Medical Center6 enrolled1 locationNCT07395050
Recruiting
Early Phase 1
Allogeneic Anti-CD7 CAR-T for Type 1 Diabetes
T1DM - Type 1 Diabetes Mellitus
Shanghai Zhongshan Hospital9 enrolled1 locationNCT07528105
Recruiting
Early Phase 1
SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan
Heart Failure With Preserved Ejection FractionType2 Diabetes
The University of Texas Health Science Center at San Antonio30 enrolled1 locationNCT05057806
Recruiting
Early Phase 1
Type 2 Diabetes and Blood Brain Barrier Improvement
Type2diabetes
University of California, Los Angeles52 enrolled1 locationNCT06322212
Recruiting
Early Phase 1
Pre-Surgical Tirzepatide-Assisted Weight Loss in Overweight and Obese Men With Intermediate Risk Prostate Cancer: A Pilot Feasibility Study
Prostate CancerDiabetes
M.D. Anderson Cancer Center30 enrolled1 locationNCT06759701
Recruiting
Early Phase 1
Effect of Arestin-Enhanced SRP on Periodontal and Glycemic Outcomes in Diabetics
Periodontitis, Diabetes Mellitus Type 2
Case Western Reserve University42 enrolled1 locationNCT07298057
Recruiting
Early Phase 1
Effect of C-peptide on Hypoglycemic Counterregulation
Type 1 DiabetesHypoglycemia
University of Cincinnati38 enrolled1 locationNCT06470295
Recruiting
Early Phase 1
Ketones, SGLT2, HFrEF
Heart Failure With Reduced Ejection FractionType2diabetes
The University of Texas Health Science Center at San Antonio71 enrolled1 locationNCT06229678
Recruiting
Early Phase 1
Crocus Sativus Tepals Water Extract in Obesity and Prediabetes
Prediabetes
University of Primorska20 enrolled1 locationNCT07261475
Recruiting
Early Phase 1
Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes
Type 2 DiabetesHeart Failure, Reduced Ejection Fraction
The University of Texas Health Science Center at San Antonio10 enrolled1 locationNCT06108076
Recruiting
Early Phase 1
Precision Dosing of Metformin in Youth With T2D
Type 2 Diabetes
University of California, San Francisco20 enrolled2 locationsNCT06120881
Recruiting
Early Phase 1
GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab
Type 1 Diabetes
Vanderbilt University Medical Center24 enrolled1 locationNCT06338553
Recruiting
Early Phase 1
Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes
Healthy VolunteerMODY2 DiabetesType 1 Diabetes Mellitus+1 more
Vanderbilt University Medical Center27 enrolled1 locationNCT06609356
Recruiting
Early Phase 1
Role of ET-1, Physical Activity, and Sedentary Behavior in Microvascular Dysfunction Following GDM
Physical InactivityEndothelial DysfunctionGestational Diabetes
Anna Stanhewicz, PhD40 enrolled1 locationNCT06547619
Recruiting
Early Phase 1
Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction
Type 2 DiabetesHealthy Aging
Medical College of Wisconsin60 enrolled1 locationNCT05593549
Recruiting
Early Phase 1
The Effects of Fluoxetine and/or DHEA
Type 1 Diabetes Mellitus
University of Maryland, Baltimore60 enrolled1 locationNCT03228732
Recruiting
Early Phase 1
Akkermansia Muciniphilia and Metabolic Side Effects of ADT
Prostate CancerObesityMetabolic Syndrome+4 more
Western University30 enrolled1 locationNCT05802121
Recruiting
Early Phase 1
Breaking up Sedentary Time to Improve Glucose Control in a Population at Risk for Developing Type 2 Diabetes
Pre-diabetes
University of Colorado, Denver66 enrolled1 locationNCT05041491
Recruiting
Early Phase 1
SGLT2i, Hepatic Glucose Production, and SNS
Type 2 Diabetes
The University of Texas Health Science Center at San Antonio22 enrolled1 locationNCT07053293
Recruiting
Early Phase 1
Regulation of Brain Glucose Metabolism in Type 1 Diabetes
Diabetes Mellitus, Type 1Hypoglycemia Unawareness
Yale University16 enrolled1 locationNCT05317455