Phase 3 Diabetes Clinical Trials
100 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 100 trials
Recruiting
Phase 3
Efficacy and Safety of KAI-9531 Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
Obesity With DiabetesOverweight With Diabetes
Kailera1,700 enrolled37 locationsNCT07284901
Recruiting
Phase 3
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Cardiovascular DiseasesHypertensionDiabetes Mellitus, Type 2
Boehringer Ingelheim11,800 enrolled1152 locationsNCT07064473
Recruiting
Phase 3
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
Type 1 Diabetes Mellitus
Sanofi723 enrolled141 locationsNCT07088068
Recruiting
Phase 3
AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight
Diabetes MellitusObesityOverweight
Novo Nordisk A/S630 enrolled73 locationsNCT07533175
Recruiting
Phase 3
Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes
Diabetes Mellitus, Type 1
vTv Therapeutics150 enrolled58 locationsNCT06334133
Recruiting
Phase 3
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Obesity or OverweightType 2 Diabetes Mellitus
Hoffmann-La Roche1,600 enrolled36 locationsNCT07351058
Recruiting
Phase 2Phase 3
Open-Label Study of Dimethyl Fumarate in Adults With Type 1 Diabetes
Type 1 Diabetes Mellitus
Nanjing Medical University96 enrolled1 locationNCT07548996
Recruiting
Phase 3
A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)
Type 2 Diabetes
Eli Lilly and Company55 enrolled51 locationsNCT06739122
Recruiting
Phase 3
A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults
Diabetes Mellitus, Type 1
Eli Lilly and Company150 enrolled107 locationsNCT07222137
Recruiting
Phase 3
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)
Diabetes Mellitus, Type 1
Eli Lilly and Company300 enrolled132 locationsNCT07222332
Recruiting
Phase 3
A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes
ObesityOverweightType 2 Diabetes
Eli Lilly and Company1,200 enrolled80 locationsNCT06993792
Recruiting
Phase 3
A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes
Diabetes Mellitus, Type 1
Novo Nordisk A/S877 enrolled193 locationsNCT07076199
Recruiting
Phase 3
Dapagliflozin in Patients With Atrial Fibrillation (DAPA-AF)
Diabetes MellitusAtrial Fibrillation
University of Oklahoma28 enrolled1 locationNCT05174052
Recruiting
Phase 3
Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease
Chronic Kidney DiseasesType 2 Diabetes Mellitus
Prokidney685 enrolled95 locationsNCT05099770
Recruiting
Phase 3
An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant
Kidney TransplantType 1 Diabetes
Vertex Pharmaceuticals Incorporated10 enrolled7 locationsNCT06832410
Recruiting
Phase 3
Efficacy and Safety of Tirzepatide Once Weekly Versus Placebo in Participants Who Are Either Obese or Overweight With Weight-Related Comorbidities (SURMOUNT-1)
ObesityOverweight (Without Type 2 Diabetes) With Weight-related Comorbidities
Hudson Biotech2,539 enrolled1 locationNCT07481747
Recruiting
Phase 2Phase 3
Mesenchymal Stem Cell and Exosome Therapy for Diabetic Erectile Dysfunction
Erectile Dysfunction With Diabetes Mellitus
Ankara City Hospital Bilkent90 enrolled1 locationNCT07480161
Recruiting
Phase 3
A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes
Diabetes Mellitus, Type 1Impaired Hypoglycemic AwarenessSevere Hypoglycemia
Vertex Pharmaceuticals Incorporated52 enrolled29 locationsNCT04786262
Recruiting
Phase 3
Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes
Type 2 Diabetes (Adult Onset)
The University of Texas Health Science Center at San Antonio256 enrolled2 locationsNCT06246799
Recruiting
Phase 3
A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome
Type 2 Diabetes (T2DM)LipidemiaMetabolic Syndrome (MetS)
NewAmsterdam Pharma300 enrolled20 locationsNCT07219602