Phase 2 Diseases Clinical Trials
149 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 149 trials
Recruiting
Phase 2
Bioenergetic Effect of Pioglitazone in CLD-PH
Pulmonary HypertensionPulmonary Hypertension Due to Lung Diseases
Emory University20 enrolled1 locationNCT06336798
Recruiting
Phase 2
Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII
Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled22 locationsNCT07326566
Recruiting
Phase 2
A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)
ObesityBody WeightOverweight+5 more
Pfizer872 enrolled65 locationsNCT07575932
Recruiting
Phase 2
A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
Inflammatory Bowel DiseasesCrohn's Disease
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)385 enrolled225 locationsNCT06226883
Recruiting
Phase 2
Effects of Treatments on Atopic Dermatitis
DermatitisEczemaSkin Diseases+2 more
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)130 enrolled1 locationNCT01631617
Recruiting
Phase 2
Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma
Lymphoproliferative DisordersImmune System DiseasesPeripheral T-cell Lymphomas
National Cancer Institute (NCI)330 enrolled2 locationsNCT03922724
Recruiting
Phase 2
Smart Walk: A Culturally Tailored Smartphone-Delivered Physical Activity Intervention for African American Women
ExerciseDiabetes MellitusPhysical Inactivity+2 more
Arizona State University210 enrolled1 locationNCT06337708
Recruiting
Phase 2
Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients
Duchenne Muscular DystrophyDMDNeuromuscular Diseases+2 more
Satellos Bioscience, Inc.51 enrolled21 locationsNCT07287189
Recruiting
Phase 2
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
ColitisInflammatory Bowel DiseasesUlcerative Colitis+1 more
Spyre Therapeutics, Inc.645 enrolled253 locationsNCT07012395
Recruiting
Phase 2
Colchicine to Reduce Coronary Artery Inflammation in People With HIV
HIV InfectionCardiovascular Diseases (CVD)
Instituto de Investigación Hospital Universitario La Paz90 enrolled4 locationsNCT07704164
Recruiting
Phase 2
Duloxetine in Inflammatory Bowel Diseases
Inflammatory Bowel Diseases
University of Pennsylvania32 enrolled1 locationNCT07431606
Recruiting
Phase 2
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
Proteinuric Kidney Diseases
Boehringer Ingelheim132 enrolled161 locationsNCT07355296
Recruiting
Phase 2
LAM-001 for the Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Pulmonary Hypertension Due to Lung Diseases and Hypoxia
OrphAI Therapeutics85 enrolled3 locationsNCT05798923
Recruiting
Phase 2
METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)
Endocrine System DiseasesImmune System DiseasesAutoimmune Diseases+6 more
University of Washington60 enrolled2 locationsNCT07699380
Recruiting
Phase 2
Transition to KPL-387 Monotherapy Dosing & Administration Study
PericarditisHeart DiseasesRecurrent Pericarditis
Kiniksa Pharmaceuticals International, plc80 enrolled39 locationsNCT07288216
Recruiting
Phase 2
H01 in Adults With Interstitial Lung Disease (The SOLIS Study)
Interstitial Lung DiseaseLung Diseases, InterstitialIdiopathic Pulmonary Fibrosis
National Institute of Environmental Health Sciences (NIEHS)37 enrolled1 locationNCT06325696
Recruiting
Phase 2
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies
Lymphoproliferative DisordersImmune System DiseasesCommon Variable Immunodeficiency+2 more
National Cancer Institute (NCI)354 enrolled2 locationsNCT02579967
Recruiting
Phase 1Phase 2
CAR-T Cells Targeting Autoimmune Diseases
Autoimmune Diseases
Shenzhen Geno-Immune Medical Institute30 enrolled1 locationNCT05459870
Recruiting
Phase 1Phase 2
Autoimmune Disease Treatment With Mesenchymal Stem Cells (MSCs) and CAR-T Cells
Autoimmune Diseases
Shenzhen Geno-Immune Medical Institute30 enrolled1 locationNCT06435897
Recruiting
Phase 2
Study to Evaluate Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene
deaf-blindRetinitis pigmentosa (RP)Retinal Disease+4 more
Laboratoires Thea81 enrolled28 locationsNCT06627179