Phase 2 Diseases Clinical Trials

144 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 144 trials

Recruiting
Phase 1Phase 2

Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection

Prostate CancerMetastatic Castration-resistant Prostate CancerUrogenital Neoplasms+3 more
Blue Earth Therapeutics Ltd82 enrolled21 locationsNCT05413850
Recruiting
Phase 2

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled5 locationsNCT07326566
Recruiting
Phase 2

Efficacy and Safety of Dalpiciclib Combined With Endocrine Adjuvant Therapy for Early HR +/HER2- Breast Cancer: a Multicenter, Prospective Clinical Study

Breast NeoplasmsBreast DiseasesCDK4/6 Inhibitor+3 more
Fujian Cancer Hospital2,000 enrolled2 locationsNCT07581834
Recruiting
Phase 2

A Study of SPY072 in Rheumatic Disease

Rheumatoid ArthritisPsoriatic ArthritisRheumatic Diseases+5 more
Spyre Therapeutics, Inc.285 enrolled64 locationsNCT07148414
Recruiting
Phase 2

Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients

Duchenne Muscular DystrophyDMDNeuromuscular Diseases+2 more
Satellos Bioscience, Inc.51 enrolled25 locationsNCT07287189
Recruiting
Phase 1Phase 2

Human Immune Response to Ixodes Scapularis Tick Bites

Lyme DiseaseTick-Borne DiseasesTick Resistance
National Institute of Allergy and Infectious Diseases (NIAID)60 enrolled1 locationNCT05036707
Recruiting
Phase 2

Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD

Insulin ResistanceChronic Kidney DiseasesFatigue+4 more
University of California, Davis80 enrolled2 locationsNCT04984226
Recruiting
Phase 2

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

ColitisInflammatory Bowel DiseasesUlcerative Colitis+1 more
Spyre Therapeutics, Inc.645 enrolled191 locationsNCT07012395
Recruiting
Phase 2

Effects of Treatments on Atopic Dermatitis

DermatitisEczemaSkin Diseases+2 more
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)130 enrolled1 locationNCT01631617
Recruiting
Phase 2

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

Lymphoproliferative DisordersImmune System DiseasesCommon Variable Immunodeficiency+2 more
National Cancer Institute (NCI)66 enrolled1 locationNCT04339777
Recruiting
Phase 2

Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus

Chronic Kidney DiseasesPruritus
Vifor Fresenius Medical Care Renal Pharma18 enrolled14 locationsNCT06593392
Recruiting
Phase 2

FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitis

Inflammatory Bowel DiseasesPrimary Sclerosing Cholangitis
University of Birmingham58 enrolled5 locationsNCT06286709
Recruiting
Phase 2

Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

Lymphoproliferative DisordersImmune System DiseasesCommon Variable Immunodeficiency+2 more
National Cancer Institute (NCI)354 enrolled2 locationsNCT02579967
Recruiting
Phase 2

PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease

Proteinuric Kidney Diseases
Boehringer Ingelheim132 enrolled147 locationsNCT07355296
Recruiting
Phase 2

NAVIGATE Kidney: A Multi-level Intervention to Reduce Kidney Health Disparities

Chronic Kidney DiseasesKidney Diseases
University of Colorado, Denver448 enrolled2 locationsNCT06810622
Recruiting
Phase 2Phase 3

Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms

Urinary IncontinenceOveractive BladderUrologic Diseases+1 more
Northwestern University66 enrolled1 locationNCT05878951
Recruiting
Phase 2

Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

Lymphoproliferative DisordersImmune System DiseasesPeripheral T-cell Lymphomas
National Cancer Institute (NCI)330 enrolled2 locationsNCT03922724
Recruiting
Phase 1Phase 2

Open-Label Study of Pocenbrodib Alone and in Combination With Abiraterone Acetate, Olaparib, or 177Lu-PSMA-617

Prostate CancerNeoplasmsNeoplasms by Site+7 more
Pathos AI, Inc.252 enrolled18 locationsNCT06785636
Recruiting
Phase 1Phase 2

Autoimmune Disease Treatment With Mesenchymal Stem Cells (MSCs) and CAR-T Cells

Autoimmune Diseases
Shenzhen Geno-Immune Medical Institute30 enrolled1 locationNCT06435897
Recruiting
Phase 2

A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD

Cardiovascular DiseasesFibrosisLung Diseases+3 more
Pulmovant, Inc.20 enrolled1 locationNCT07333183