Disorders of Consciousness Clinical Trials

9 recruiting

Frequently Asked Questions

Common questions about Disorders of Consciousness clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 114 of 14 trials

Recruiting
Not Applicable

Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Patients With Disorders of Consciousness

Disorders of Consciousness
Zhujiang Hospital20 enrolled1 locationNCT07284732
Recruiting

Assessment of Consciousness With CRS-R and SECONDs

Disorders of Consciousness Due to Severe Brain InjuryMinimally Conscious StateUnresponsive Wakefulness Syndrome
BDH-Klinik Hessisch Oldendorf110 enrolled1 locationNCT07456020
Recruiting
Not Applicable

Promoting Recovery After Brain Injury Using Focused Ultrasound

Consciousness DisordersDisorders of Consciousness Due to Severe Brain Injury
Massachusetts General Hospital36 enrolled2 locationsNCT07277309
Recruiting
Not Applicable

Window On the Brain

Disorders of Consciousness
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta100 enrolled4 locationsNCT06693492
Recruiting
Early Phase 1

REstoring CONsciousness With NEurostimulation of the Central Thalamus: The RECONNECT Study

Disorders of Consciousness
Samuel Snider, MD2 enrolled1 locationNCT07228286
Recruiting
Not Applicable

Ultrasound Stimulation for Patients in a Disorder of Consciousness

Consciousness DisordersDisorders of Consciousness Due to Severe Brain Injury
University of California, Los Angeles60 enrolled4 locationsNCT06939348
Recruiting

Diagnosis Value of Interoceptive EEG Indicators by Rectal Stimulation in DoC

Disorders of Consciousness
YiLin Zhao45 enrolled2 locationsNCT07208942
Recruiting

Spontaneous Eye Blinking in Disorders of Consciousness

Disorders of Consciousness
Fondazione Don Carlo Gnocchi Onlus70 enrolled8 locationsNCT06323031
Recruiting
Not Applicable

Consciousness Prognosis Evaluation Using Olfactory Stimulations in Comatose Patients)

Disorders of Consciousness Due to Severe Brain Injury
Centre Hospitalier St Anne96 enrolled1 locationNCT07127224
Recruiting

What is the Perceived Role of Risk in DOC Healthcare.

Disorders of Consciousness
University of Nottingham40 enrolled2 locationsNCT06647433
Recruiting

Tickle Stimulation in Disorders of Consciousness (DoC)

Disorders of Consciousness
Anna Estraneo45 enrolled2 locationsNCT06922162
Recruiting
Not Applicable

Transcranial Temporal Interference Stimulation In Severely Brain Injured Patients With Disorders of Consciousness

Severe Brain InjuryDisorders of ConsciousnessMinimally Conscious State+1 more
Xijing Hospital10 enrolled2 locationsNCT06851156
Recruiting

Brain Network Analysis of Anesthesia Characteristics in Patients With pDoC Based on PSG

Disorders of Consciousness
Beijing Tiantan Hospital60 enrolled1 locationNCT06157008
Recruiting
Not Applicable

Effects of Esketamine on Consciousness-related Brain Network Characteristics in Patients With Prolonged Disorders of Consciousness

Prolonged Disorders of Consciousness
Beijing Tiantan Hospital80 enrolled1 locationNCT06473285