Phase 2 Dysplasia Clinical Trials

36 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 36 trials

Recruiting
Phase 2

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Acute Myeloid LeukemiaAcute Myeloid Leukemia Post Cytotoxic TherapyAcute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm+1 more
National Cancer Institute (NCI)335 enrolled221 locationsNCT05554406
Recruiting
Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid LeukemiaMyelodysplastic SyndromeAcute Myeloid Leukemia Post Cytotoxic Therapy+2 more
National Cancer Institute (NCI)2,000 enrolled347 locationsNCT05564390
Recruiting
Phase 2

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

Intraventricular hemorrhageChronic lung disease of prematurityBronchopulmonary Dysplasia+1 more
OHB Neonatology Ltd.338 enrolled72 locationsNCT03253263
Recruiting
Phase 2Phase 3

Efficacy and Safety of Zelpultide Alfa in Preterm Neonates at High Risk of Developing Bronchopulmonary Dysplasia (BPD)

Bronchopulmonary Dysplasia
Airway Therapeutics, Inc.366 enrolled50 locationsNCT06897839
Recruiting
Phase 1Phase 2

PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia

Critical IllnessBronchopulmonary Dysplasia (BPD)Premature Births
Duke University28 enrolled5 locationsNCT07101640
Recruiting
Phase 1Phase 2

Safety and Efficacy of PTH-IA

Jansen's Metaphyseal Chondrodysplasia
National Institute of Dental and Craniofacial Research (NIDCR)12 enrolled1 locationNCT07541209
Recruiting
Phase 2

IVIG Trial for the Treatment of Bronchopulmonary Dysplasia

Bronchopulmonary Dysplasia
International Peace Maternity and Child Health Hospital20 enrolled1 locationNCT06925360
Recruiting
Phase 2

Personalized NK Cell Therapy in CBT

Acute Lymphoblastic LeukemiaMyelodysplastic SyndromeChronic Myelomonocytic Leukemia+23 more
M.D. Anderson Cancer Center100 enrolled1 locationNCT02727803
Recruiting
Phase 2

To Assess the Efficacy, Safety, and Tolerability of INCB000928 in Participants With Fibrodysplasia Ossificans Progressiva

Fibrodysplasia Ossificans Progressiva (FOP)
Incyte Corporation98 enrolled24 locationsNCT05090891
Recruiting
Phase 2

Phase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic Abnormalities

HPV InfectionASC-USUterine Cervical Dysplasia+3 more
Amplexd Therapeutics, Inc.45 enrolled1 locationNCT07572396
Recruiting
Phase 2

Lipid Infusions to Optimize Nutrition Trial

Bronchopulmonary Dysplasianeurodevelopmental impairment
The University of Texas Health Science Center, Houston230 enrolled1 locationNCT06915441
Recruiting
Phase 2

Effects of IVIG for BPD in Preterm Infant Born at 28 Weeks and Below

Bronchopulmonary Dysplasia
International Peace Maternity and Child Health Hospital29 enrolled1 locationNCT07561125
Recruiting
Phase 2Phase 3

Can PLIA Reduce Early Post-operative Pain After PAO Surgery?

Hip Dysplasia
Michael C Willey120 enrolled1 locationNCT06519955
Recruiting
Phase 2

Oral Bevacizumab-800CW and Cetuximab-800CW Administration to Detect Early Esophageal Adenocarcinomas

Esophageal AdenocarcinomaBarrett's Esophagus Without DysplasiaBarrett Oesophagitis With Dysplasia
University Medical Center Groningen25 enrolled1 locationNCT05745857
Recruiting
Phase 2

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAcute Leukemia+21 more
Masonic Cancer Center, University of Minnesota70 enrolled1 locationNCT05735717
Recruiting
Phase 1Phase 2

Topical Imiquimod Treatment of Oral Dysplasia

Leukoplakia, OralOral DysplasiaLeukoplakia
University of Southern California20 enrolled1 locationNCT07210775
Recruiting
Phase 2

Effectiveness and Performance of an Optical Biopsy Technology for Esophageal Cancer in Brazil and the United States

Suspected or Known Squamous Cell NeoplasiaPrior History of Squamous Cell Dysplasia and /or Neoplasia
Baylor College of Medicine200 enrolled4 locationsNCT06435286
Recruiting
Phase 2

Blockade of the Renin-angiotensin-aldosterone System in Patients With ARVD

Arrhythmogenic Right Ventricular Dysplasia
Hospices Civils de Lyon120 enrolled13 locationsNCT03593317
Recruiting
Phase 2

A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia

Oral Carcinoma in SituOropharyngeal DysplasiaOral Cavity Dysplasia
Elizabeth J Franzmann32 enrolled1 locationNCT05865028
Recruiting
Phase 2

Dose-Expansion Study of Low Dose Post-Transplant Cyclophosphamide/Tacrolimus/Ruxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxis in Myeloablative Allogeneic Peripheral Blood Stem Cell Transplantation

LeukemiaChronic Myelomonocytic LeukemiaMyelodysplasia
Hannah Choe, MD124 enrolled1 locationNCT07249346