Phase 2 Dysplasia Clinical Trials

33 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 33 trials

Recruiting
Phase 2

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Acute Myeloid LeukemiaAcute Myeloid Leukemia Post Cytotoxic TherapyAcute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm+1 more
National Cancer Institute (NCI)335 enrolled220 locationsNCT05554406
Recruiting
Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Acute Myeloid LeukemiaMyelodysplastic SyndromeAcute Myeloid Leukemia Post Cytotoxic Therapy+2 more
National Cancer Institute (NCI)2,000 enrolled346 locationsNCT05564390
Recruiting
Phase 2

Effects of IVIG for BPD in Preterm Infant Born at 28 Weeks and Below

Bronchopulmonary Dysplasia
International Peace Maternity and Child Health Hospital29 enrolled1 locationNCT07561125
Recruiting
Phase 2Phase 3

Can PLIA Reduce Early Post-operative Pain After PAO Surgery?

Hip Dysplasia
Michael C Willey120 enrolled1 locationNCT06519955
Recruiting
Phase 2

Oral Bevacizumab-800CW and Cetuximab-800CW Administration to Detect Early Esophageal Adenocarcinomas

Esophageal AdenocarcinomaBarrett's Esophagus Without DysplasiaBarrett Oesophagitis With Dysplasia
University Medical Center Groningen25 enrolled1 locationNCT05745857
Recruiting
Phase 2

MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAcute Leukemia+21 more
Masonic Cancer Center, University of Minnesota70 enrolled1 locationNCT05735717
Recruiting
Phase 2

IVIG Trial for the Treatment of Bronchopulmonary Dysplasia

Bronchopulmonary Dysplasia
International Peace Maternity and Child Health Hospital20 enrolled1 locationNCT06925360
Recruiting
Phase 1Phase 2

PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia

Critical IllnessBronchopulmonary Dysplasia (BPD)Premature Births
Duke University28 enrolled4 locationsNCT07101640
Recruiting
Phase 1Phase 2

Topical Imiquimod Treatment of Oral Dysplasia

Oral Dysplasia
University of Southern California20 enrolled1 locationNCT07210775
Recruiting
Phase 2

Effectiveness and Performance of an Optical Biopsy Technology for Esophageal Cancer in Brazil and the United States

Suspected or Known Squamous Cell NeoplasiaPrior History of Squamous Cell Dysplasia and /or Neoplasia
Baylor College of Medicine200 enrolled4 locationsNCT06435286
Recruiting
Phase 2Phase 3

Efficacy and Safety of Zelpultide Alfa in Preterm Neonates at High Risk of Developing Bronchopulmonary Dysplasia (BPD)

Bronchopulmonary Dysplasia
Airway Therapeutics, Inc.366 enrolled20 locationsNCT06897839
Recruiting
Phase 2

Blockade of the Renin-angiotensin-aldosterone System in Patients With ARVD

Arrhythmogenic Right Ventricular Dysplasia
Hospices Civils de Lyon120 enrolled13 locationsNCT03593317
Recruiting
Phase 2

A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia

Oral Carcinoma in SituOropharyngeal DysplasiaOral Cavity Dysplasia
Elizabeth J Franzmann32 enrolled1 locationNCT05865028
Recruiting
Phase 2

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

Bronchopulmonary Dysplasia
OHB Neonatology Ltd.338 enrolled66 locationsNCT03253263
Recruiting
Phase 2

Dose-Expansion Study of Low Dose Post-Transplant Cyclophosphamide/Tacrolimus/Ruxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxis in Myeloablative Allogeneic Peripheral Blood Stem Cell Transplantation

LeukemiaChronic Myelomonocytic LeukemiaMyelodysplasia
Hannah Choe, MD124 enrolled1 locationNCT07249346
Recruiting
Phase 2

To Assess the Efficacy, Safety, and Tolerability of INCB000928 in Participants With Fibrodysplasia Ossificans Progressiva

Fibrodysplasia Ossificans Progressiva (FOP)
Incyte Corporation98 enrolled27 locationsNCT05090891
Recruiting
Phase 2

Personalized NK Cell Therapy in CBT

Acute Lymphoblastic LeukemiaMyelodysplastic SyndromeChronic Myelomonocytic Leukemia+23 more
M.D. Anderson Cancer Center100 enrolled1 locationNCT02727803
Recruiting
Phase 2

Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)

HPV InfectionCervical DysplasiaCIN 2/3+2 more
Frantz Viral Therapeutics, LLC78 enrolled7 locationsNCT04098744
Recruiting
Phase 2

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3)

Vulvar DiseasesHPV InfectionHigh Grade Intraepithelial Neoplasia+10 more
Frantz Viral Therapeutics, LLC27 enrolled5 locationsNCT06075264
Recruiting
Phase 1Phase 2

Astroscape: A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II

Tuberous Sclerosis ComplexFocal Cortical Dysplasia
GRIN Therapeutics, Inc.30 enrolled20 locationsNCT06392009