Early Phase 1 ECT Clinical Trials
79 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 79 trials
Recruiting
Early Phase 1
The Safety and Efficacy of Allogeneic CD70 CAR-T Therapy in Unresectable or Metastatic Clear Cell Renal Cell Carcinoma
Unresectable or Metastatic Clear Cell Renal Cell Carcinoma
Chinese PLA General Hospital30 enrolled3 locationsNCT07645690
Recruiting
Early Phase 1
Effect of Rose Odor Exposure on Ictal Apnea
EpilepsySudden Unexpected Death in Epilepsy
Vanderbilt University Medical Center40 enrolled1 locationNCT07116421
Recruiting
Early Phase 1
Hearts on Fire: Targeting Inflammation in Heart Failure With Preserved Ejection Fraction
Heart Failure With Preserved Ejection Fraction (HFpEF)
University of Florida70 enrolled1 locationNCT07634640
Recruiting
Early Phase 1
Attentional Mechanisms in SCD
Subjective Cognitive Decline
Vanderbilt University Medical Center80 enrolled1 locationNCT06002477
Recruiting
Early Phase 1
CDH17 CAR-T Therapy in Advanced Malignant Solid Tumors
Biliary Tract CancerColorectal CarcinomaGastric Cancer, Metastatic+2 more
Zhejiang University36 enrolled1 locationNCT06937567
Recruiting
Early Phase 1
Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer
Rectal AdenocarcinomaStage II Rectal Cancer AJCC v8Stage III Rectal Cancer AJCC v8+6 more
M.D. Anderson Cancer Center120 enrolled1 locationNCT03594630
Recruiting
Early Phase 1
Botensilimab, Balstilimab, and SBRT in Colorectal Cancer
Non-MSI-H or pMMR Colorectal Cancer With Liver Metastasis
Massachusetts General Hospital15 enrolled1 locationNCT07128355
Recruiting
Early Phase 1
Vitamin D in Patients With Stage I-III Colon Cancer or Resectable Colon Cancer Liver Metastases
Stage, Colon CancerStage I-III Colon CancerStage IV Colon Cancer With Resectable Liver Metastases
Dana-Farber Cancer Institute80 enrolled1 locationNCT02172651
Recruiting
Early Phase 1
Radiocaine Safety Study
Healthy Subjects
Lutroo Imaging LLC6 enrolled1 locationNCT07081217
Recruiting
Early Phase 1
Clinical Study of B001 Injection in Subjects With Neuromyelitis Optic Spectrum Disorder (NMOSD)
NMO Spectrum Disorder
Shanghai Pharmaceuticals Holding Co., Ltd45 enrolled4 locationsNCT05145361
Recruiting
Early Phase 1
Cannabis Use, Cognition, and the Endocannabinoid System in HIV
HIV-1-infection
University of California, San Diego138 enrolled1 locationNCT04883255
Recruiting
Early Phase 1
SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan
Heart Failure With Preserved Ejection FractionType2 Diabetes
The University of Texas Health Science Center at San Antonio30 enrolled1 locationNCT05057806
Recruiting
Early Phase 1
Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA CAR-NK Cell Injection for the Treatment of Refractory Pediatric Rheumatic Diseases
Systemic Lupus Erythematosus (SLE)Rheumatic DiseasesPediatric Rheumatological Condition (i.e., Arthritis, SLE, Kawasaki's Disaese)+1 more
The Children's Hospital of Zhejiang University School of Medicine36 enrolled1 locationNCT07490041
Recruiting
Early Phase 1
INFINITIVE: ImmuNotherapy For PatIeNts wIth colorecTal LIVer MEtastases
Colorectal Cancer Metastatic
Northwell Health10 enrolled1 locationNCT07172282
Recruiting
Early Phase 1
Single-tracer Multiparametric PET Imaging
Cardiovascular DiseaseHealthy Subjects
University of California, Davis60 enrolled1 locationNCT06014515
Recruiting
Early Phase 1
Targeted Pathway Inhibition in Patients With Pancreatic Cancer
Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Stage IV Pancreatic Cancer AJCC v8+5 more
OHSU Knight Cancer Institute90 enrolled1 locationNCT04005690
Recruiting
Early Phase 1
Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis
Colorectal Cancer Metastatic
Northwell Health10 enrolled2 locationsNCT07193862
Recruiting
Early Phase 1
Ketamine for Shoulder Pain Following Laparoscopic Gastric Sleeve Surgery
Pain ManagementLaparascopic Sleeve Gastrectomy
King Abdullah University Hospital50 enrolled1 locationNCT07429916
Recruiting
Early Phase 1
Effect of an 8-Week Pickleball Program for Adults With Autism: A Feasibility Trial With a Delayed-Control Design
Autism Spectrum Disorder
Penn State University50 enrolled1 locationNCT07432776
Recruiting
Early Phase 1
Safety and Efficacy of Umbilical Cord Blood-Derived Mesenchymal Stem Cells in the Treatment of Long-Term Cytopenia After CAR-T Therapy
Immune Effector Cell Associated Hematotoxicity
Institute of Hematology & Blood Diseases Hospital, China15 enrolled1 locationNCT07212335