Phase 2 Ejection Fraction Clinical Trials
23 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 23 trials
Recruiting
Phase 2
A Phase II Clinical Trial of HRS-1893 in the Treatment of Heart Failure With Preserved Ejection Fraction
Heart Failure With Preserved Ejection Fraction
Shandong Suncadia Medicine Co., Ltd.48 enrolled1 locationNCT07269717
Recruiting
Phase 2
CAMEO-FONTAN -Dapagliflozin in the Failing Fontan Circulation
HFpEF - Heart Failure With Preserved Ejection FractionFontan CirculationSingle Ventricle Heart Disease
Mayo Clinic27 enrolled1 locationNCT06762964
Recruiting
Phase 2
Coronary Artery Stents in Heart Failure With Preserved Ejection Fraction
Coronary Artery DiseaseHeart Failure With Preserved Ejection Fraction (HFpEF)
King's College London350 enrolled1 locationNCT07560436
Recruiting
Phase 2
A Study of 68Ga-Fibroblast Activation Protein Inhibitor (FAPI) Positron Emission Tomography in Heart Failure
Heart Failure With Preserved Ejection Fraction
Mayo Clinic35 enrolled1 locationNCT07083011
Recruiting
Phase 2
SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial
Heart Failure With Preserved Ejection Fraction
University of Pennsylvania53 enrolled1 locationNCT05138575
Recruiting
Phase 1Phase 2
Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease
Heart FailureChronic Kidney DiseasesKidney Diseases+1 more
Northwestern University60 enrolled1 locationNCT05719714
Recruiting
Phase 2
A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)
Pulmonary HypertensionHeart Failure With Preserved Ejection Fraction
Tectonic Therapeutic180 enrolled86 locationsNCT06616974
Recruiting
Phase 2
Swedish Cardiac And Renal Failure Study-1
Chronic Kidney DiseaseHFrEF - Heart Failure With Reduced Ejection Fraction
Karolinska Institutet40 enrolled1 locationNCT07029503
Recruiting
Phase 2Phase 3
Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy
Heart Failure With Reduced Ejection FractionHeart Rhythm Disorder
Herlev and Gentofte Hospital348 enrolled1 locationNCT06128980
Recruiting
Phase 2
Allopurinol Improves Heart Function in African Americans With Resistant Hypertension
Heart Failure Preserved Ejection FractionResistant Hypertension
VA Office of Research and Development50 enrolled1 locationNCT05888233
Recruiting
Phase 2
Study of JK07 in Patients With Heart Failure and WHO Group 2 Combined Post- and Pre-Capillary Pulmonary Hypertension
HFrEF - Heart Failure With Reduced Ejection FractionHFpEF - Heart Failure With Preserved Ejection FractionGroup 2 Pulmonary Hypertension
Salubris Biotherapeutics Inc30 enrolled1 locationNCT07221513
Recruiting
Phase 2
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
Symptomatic Heart Failure With Preserved Ejection Fraction (HFpEF)
Cytokinetics60 enrolled24 locationsNCT06793371
Recruiting
Phase 2
Study on the Efficacy and Safety of HRS-7535 in Patients With Mild Decrease in Ejection Fraction/Preserved Ejection Fraction Heart Failure and Obesity
Adults With Heart Failure, Mild Decrease in Ejection Fraction/Preserved Ejection Fraction, and Obesity
Shandong Suncadia Medicine Co., Ltd.225 enrolled1 locationNCT06820099
Recruiting
Phase 2Phase 3
Tailored Exercise Training Study Among Adults With HFpEF
Diabetic CardiomyopathiesHFpEF - Heart Failure With Preserved Ejection Fraction
University of Texas Southwestern Medical Center120 enrolled1 locationNCT07223242
Recruiting
Phase 2Phase 3
A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction
Diabetes Mellitus, Type 2Heart Failure With Preserved Ejection FractionHeart Failure, Diastolic+2 more
University of Leicester63 enrolled3 locationsNCT05887271
Recruiting
Phase 2
Study of JK07 in Patients With Chronic Heart Failure
Heart Failure With Reduced Ejection FractionHeart Failure With Preserved Ejection Fraction
Salubris Biotherapeutics Inc282 enrolled62 locationsNCT06369298
Recruiting
Phase 2
A Study of IBI362 in Subjects With HFpEF or HFmrEF Combined With Obesity
ObesityHeart Failure With Preserved Ejection Fraction (HFpEF)Heart Failure With Mildly Reduced Ejection Fraction
Innovent Biologics (Suzhou) Co. Ltd.141 enrolled1 locationNCT06862908
Recruiting
Phase 2
Matching Perfusion and Metabolic Activity in HFpEF
Heart Failure With Preserved Ejection Fraction
University of Pennsylvania53 enrolled1 locationNCT04913805
Recruiting
Phase 1Phase 2
Colchicine in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction
HFpEF - Heart Failure With Preserved Ejection FractionColchicine
I.M. Sechenov First Moscow State Medical University40 enrolled2 locationsNCT05637398
Recruiting
Phase 2
Vsling™ I: Clinical Evaluation of the Vsling™ Device for Ventricular Repair in Patients With Heart Failure
Heart Failure With Reduced Ejection Fraction
Cardiac Success20 enrolled5 locationsNCT06851949