Phase 2 Encephalopathy Clinical Trials
15 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–15 of 15 trials
Recruiting
Phase 2
A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures
Neonatal EncephalopathyNeonatal SeizureSeizure Newborn+1 more
University of California, San Diego133 enrolled5 locationsNCT05610085
Recruiting
Phase 2
Intravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot Study
Progressive Multifocal Leukoencephalopathy
National Institute of Neurological Disorders and Stroke (NINDS)24 enrolled1 locationNCT07511049
Recruiting
Phase 1Phase 2
A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy
Epileptic Encephalopathy
Institut de Recherches Internationales Servier20 enrolled16 locationsNCT07227857
Recruiting
Phase 2
TReatment for ImmUne Mediated PathopHysiology
acute liver injuryImmune DysregulationHepatic Encephalopathy+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)163 enrolled24 locationsNCT04862221
Recruiting
Phase 2
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia
Hypoxic-ischemic encephalopathy.
ReAlta Life Sciences, Inc.70 enrolled15 locationsNCT05778188
Recruiting
Phase 2
Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement
CirrhosisHepatic Encephalopathy
Hunter Holmes Mcguire Veteran Affairs Medical Center30 enrolled1 locationNCT06052176
Recruiting
Phase 2
T-cell Therapy in Patients With PML
Progressive Multifocal Leucoencephalopathy (PML)
Hannover Medical School23 enrolled6 locationsNCT06990087
Recruiting
Phase 2
Assess Safety and Efficacy of Sovateltide in Hypoxic-ischemic Encephalopathy
Neonatal EncephalopathyNeonatal AsphyxiaHypoxic-ischemic encephalopathy.
Pharmazz, Inc.40 enrolled4 locationsNCT05514340
Not Yet Recruiting
Phase 2Phase 3
Effectiveness and safety of riluzole for the treatment of seizures in individuals with SCN8A developmental and epileptic encephalopathy (SCN8A-DEE).
SCN8A developmental and epileptic encephalopathy
University of Melbourne5 enrolled1 locationACTRN12625000845437
Recruiting
Phase 1Phase 2
Retina is a Marker for Cerebrovascular Heath
Cerebral Small Vessel DiseasesCerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and LeukoencephalopathyCerebral Microbleeding+1 more
Mayo Clinic100 enrolled1 locationNCT04753970
Recruiting
Phase 2
Deoxynucleosides Pyrimidines as Treatment for Mitochondrial Depletion Syndrome
Mitochondrial DiseasesMitochondrial Metabolism DisordersMitochondrial Encephalomyopathy+2 more
Kenneth Myers, MD200 enrolled1 locationNCT04802707
Recruiting
Phase 2
buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest
SeizuresStatus EpilepticusHypoxia-Ischemia, Brain+4 more
University of California, San Francisco30 enrolled1 locationNCT05851391
Recruiting
Phase 2
Treatment of Neonatal Encephalopathy With Oral Sildenafil Suspension to Repair Brain Injury Secondary to Birth Asphyxia
Neonatal Encephalopathy
Pia Wintermark60 enrolled2 locationsNCT06098833
Not Yet Recruiting
Phase 2
Dose-response study of probiotics in sick term and late preterm infants: the PRINS-2 trial
feed intolerancegastroschisishypoxic ischaemic encephalopathy+1 more
Child and Adolescent health Service108 enrolled1 locationACTRN12624001428550
Recruiting
Phase 1Phase 2
Neonatal Hypoxic Ischemic Encephalopathy : Safety and Feasibility Study of a Curative Treatment With Autologous Cord Blood Stem Cells
neonatal hypoxic ischaemic encephalopathy
Assistance Publique Hopitaux De Marseille20 enrolled1 locationNCT02881970