Phase 3 Encephalopathy Clinical Trials
11 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–11 of 11 trials
Recruiting
Phase 3
A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)
Developmental and Epileptic Encephalopathy
Longboard Pharmaceuticals320 enrolled109 locationsNCT06719141
Recruiting
Phase 3
Cooling in Mild Encephalopathy
Neonatal EncephalopathyNewborn Asphyxia
Imperial College London426 enrolled39 locationsNCT05889507
Recruiting
Phase 3
Neonatal Brain Ultrasound With CEUS and Elastography
Neonatal Hypoxic Ischemic EncephalopathyNeonatal StrokeNeonatal Encephalopathy, Unspecified
Turku University Hospital100 enrolled1 locationNCT05648812
Recruiting
Phase 3
A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine
Developmental and Epileptic Encephalopathy 1
Praxis Precision Medicines160 enrolled5 locationsNCT07010471
Recruiting
Phase 3
A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety
Epileptic EncephalopathySCN2A Encephalopathy
Praxis Precision Medicines50 enrolled2 locationsNCT07019922
Not Yet Recruiting
Phase 2Phase 3
Effectiveness and safety of riluzole for the treatment of seizures in individuals with SCN8A developmental and epileptic encephalopathy (SCN8A-DEE).
SCN8A developmental and epileptic encephalopathy
University of Melbourne5 enrolled1 locationACTRN12625000845437
Recruiting
Phase 3
Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease
Alzheimer DiseaseChronic Traumatic Encephalopathy
CereMark Pharma, LLC230 enrolled1 locationNCT06254469
Recruiting
Phase 3
Erythropoietin for Neonatal Encephalopathy in LMIC (EMBRACE Trial)
EncephalopathyErythropoietinNewborn Asphyxia
Imperial College London504 enrolled10 locationsNCT05395195
Recruiting
Phase 3
Efficacy and Safety of Nitazoxanide in Preventing Recurrence of Hepatic Encephalopathy
Hepatic Encephalopathy
Tanta University60 enrolled1 locationNCT04161053
Completed
Phase 3
PAEAN – Erythropoietin for hypoxic ischaemic encephalopathy in newborns
neonatal hypoxic ischaemic encephalopathy
University of Sydney300 enrolled21 locationsACTRN12614000669695
Recruiting
Phase 3
A trial to determine if cooling newborn infants at risk of brain damage improves outcome
Term infants with hypoxic ischaemic encephalopathy
Murdoch Children's Research Institute300 enrolled1 locationACTRN12606000036516