Phase 3 Endometrial Cancer Clinical Trials
18 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–18 of 18 trials
Recruiting
Phase 3
A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer
Endometrial Cancer
BioNTech SE480 enrolled132 locationsNCT06340568
Recruiting
Phase 3
Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma
Endometrial Cancer
Karyopharm Therapeutics Inc276 enrolled217 locationsNCT05611931
Recruiting
Phase 3
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Endometrial Cancer
Merck Sharp & Dohme LLC1,123 enrolled245 locationsNCT06952504
Recruiting
Phase 3
Vaginal Cuff Brachytherapy Fractionation Study
Endometrial Cancer
Kara Romano, MD258 enrolled3 locationsNCT03785288
Recruiting
Phase 3
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)
Endometrial CancerMalignant Solid Tumour
AstraZeneca700 enrolled307 locationsNCT07044336
Recruiting
Phase 3
DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer
Endometrial Cancer
AstraZeneca600 enrolled249 locationsNCT06989112
Recruiting
Phase 3
Prehabilitation in Gynaecological Cancer Patients
Ovarian CancerEndometrial CancerOvarian Cancer Stage III+2 more
Charles University, Czech Republic64 enrolled1 locationNCT04789694
Recruiting
Phase 2Phase 3
Refining Fertility-sparing Treatment in Endometrial Carcinoma Based on Molecular Classification
Endometrial CancerFertility
Fudan University260 enrolled2 locationsNCT07319429
Recruiting
Phase 3
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
Endometrial CancerRecurrent or Progressive Endometrial Cancer
Genmab544 enrolled51 locationsNCT07166094
Recruiting
Phase 3
Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer
Endometrial Cancer
Daiichi Sankyo710 enrolled40 locationsNCT07022483
Recruiting
Phase 3
Sentinel Node Biopsy in Endometrial Cancer
SurgerySentinel Lymph NodeEndometrial Cancer Stage I
Queensland Centre for Gynaecological Cancer760 enrolled19 locationsNCT04073706
Recruiting
Phase 3
Randomized Phase III Trial Testing Maintenance Olaparib Versus Observation After Adjuvant Chemoradiation for p53abn Endometrial Cancer
Endometrial Cancerp53abn
Gustave Roussy, Cancer Campus, Grand Paris554 enrolled15 locationsNCT06712472
Recruiting
Phase 2Phase 3
Trop2-targeted immunoPET Imaging of Solid Tumors
Liver CancerOvarian CancerCervical Cancer+11 more
RenJi Hospital400 enrolled1 locationNCT06851663
Recruiting
Phase 3
Study of Fruquintinib Plus Sintilimab for Treatment of Advanced Endometrial Cancer
Advanced Endometrial Cancer
Hutchmed412 enrolled17 locationsNCT06584032
Recruiting
Phase 2Phase 3
Refining Adjuvant Treatment IN Endometrial Cancer Based On Molecular Features
Endometrial Cancer
Leiden University Medical Center1,615 enrolled14 locationsNCT05255653
Recruiting
Phase 2Phase 3
Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer
Endometrial Cancer
Kartos Therapeutics, Inc.268 enrolled83 locationsNCT05797831
Recruiting
Phase 2Phase 3
Value of LNG-IUS as Fertility-preserving Treatment of EAH and EC
Endometrial CancerAtypical Endometrial Hyperplasia
West China Second University Hospital224 enrolled1 locationNCT03463252
Completed
Phase 3
Atezolizumab Trial in Endometrial cancer.
Endometrial Cancer
The University of Sydney50 enrolled21 locationsACTRN12619000900112