Phase 2 Esophageal Cancer Clinical Trials
77 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 77 trials
Recruiting
Phase 2
A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
Breast CancerColorectal, CancerEsophageal Cancer+9 more
Jazz Pharmaceuticals200 enrolled28 locationsNCT06695845
Recruiting
Phase 1Phase 2
Lead-212 PSV359 Therapy for Patients With Solid Tumors
Colorectal, CancerEsophageal CancerGastric Cancer+5 more
Perspective Therapeutics112 enrolled8 locationsNCT06710756
Recruiting
Phase 2
Single Dose Investigator Initiated Pilot Study to Investigate CYTALUX (Pafolacianine) for Intraoperative Detection of Malignant Tissue in Subjects Undergoing Surgical Resection for Cancer.
Gynecologic CancersEsophageal CancerGastrointestinal Cancers
John Waters50 enrolled1 locationNCT07039526
Recruiting
Phase 2
BEFAST Study, [68Ga]Ga-FAPI Total Body PET/CT for Better and Faster Imaging in Cancer
Gastroesophageal Cancer (GC)Pancreatic Cancer, Adult
Barbara Malene Fischer90 enrolled1 locationNCT07629609
Recruiting
Phase 2
A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer
Esophageal CancerGastric AdenocarcinomaHER2 Gene Mutation
Memorial Sloan Kettering Cancer Center49 enrolled10 locationsNCT06123338
Recruiting
Phase 2
DCRT vs. Surgery in Resectable ESCC Patient Achiving cCR/PR After nCI
Esophageal Cancer
Tianjin Medical University Cancer Institute and Hospital120 enrolled1 locationNCT07162506
Recruiting
Phase 1Phase 2
Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)
Esophageal CancerEsophageal NeoplasmsGastroesophageal Junction+1 more
Merck Sharp & Dohme LLC160 enrolled51 locationsNCT06469944
Recruiting
Phase 2
Chemoradiation Plus Iparomlimab Consolidation in Older With ESCC
Esophageal Cancer
Tianjin Medical University Cancer Institute and Hospital52 enrolled1 locationNCT07038629
Recruiting
Phase 2
A Phase II Clinical Study to Evaluate HLX43 in Patients With Recurrent/Metastatic ESCC Failed or Intolerance to Standard Therapy
Esophageal Cancer
Shanghai Henlius Biotech102 enrolled1 locationNCT06769113
Recruiting
Phase 2
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Breast CancerEsophageal CancerGastric Cancer+11 more
Daiichi Sankyo740 enrolled85 locationsNCT06172478
Recruiting
Phase 1Phase 2
Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)
Esophageal CancerEsophageal NeoplasmsGastroesophageal Junction+1 more
Merck Sharp & Dohme LLC210 enrolled45 locationsNCT06445972
Recruiting
Phase 2
A Trial of Palliative Chemotherapy, Radiation and Immune Treatment for Oesophageal Cancer: PALEO Study
Esophageal Cancer
Australasian Gastro-Intestinal Trials Group54 enrolled9 locationsNCT06290505
Recruiting
Phase 2Phase 3
Timing of Minimally Invasive Local Treatment After First-Line Systemic Therapy in Oligometastatic Esophageal or Gastric Adenocarcinoma
Esophageal CancerEsophageal CarcinomaGastric (Stomach) Cancer+3 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)290 enrolled2 locationsNCT07000253
Recruiting
Phase 1Phase 2
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
Breast CancerEsophageal CancerPancreatic Cancer+13 more
ModeX Therapeutics, An OPKO Health Company285 enrolled6 locationsNCT06239194
Recruiting
Phase 2
Patient Preference for Subcutaneous vs. Intravenous Immune Therapy
Esophageal CancerCervical CancerHepatocellular Carcinoma+9 more
Diwakar Davar880 enrolled1 locationNCT07223424
Recruiting
Phase 2
Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric Cancer
Stage IV Esophageal Cancer AJCC v7Stage IV Gastric Cancer AJCC v7Gastric Adenocarcinoma+2 more
M.D. Anderson Cancer Center100 enrolled1 locationNCT03161522
Recruiting
Phase 2
HEARTS Trial for Thoracic Cancers
Non-Small Cell Lung Cancer (Stage III)Esophageal Cancer Stage I-IIIEsophagogastric Cancer Stage I-III+2 more
University of Wisconsin, Madison60 enrolled1 locationNCT07132918
Recruiting
Phase 2
A Study of Bemosubaiabimab Combined With Anlotinib and Radiotherapy and Chemotherapy for the Treatment of Oligometastatic Esophageal Cancer
Esophageal Cancer
The First Affiliated Hospital with Nanjing Medical University28 enrolled1 locationNCT07455019
Recruiting
Phase 1Phase 2
Clinical Trial Evaluating TQB6411 Injection in Subjects With Esophageal Cancer
Esophageal Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.105 enrolled30 locationsNCT07367516
Recruiting
Phase 1Phase 2
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
Colorectal, CancerEsophageal CancerGastric Cancer+18 more
Neonc Technologies, Inc.134 enrolled6 locationsNCT06047379