Phase 2 Esophageal Cancer Clinical Trials
62 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 62 trials
Recruiting
Phase 1Phase 2
Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)
Esophageal CancerEsophageal NeoplasmsGastroesophageal Junction+1 more
Merck Sharp & Dohme LLC210 enrolled44 locationsNCT06445972
Recruiting
Phase 1Phase 2
Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)
Esophageal CancerEsophageal NeoplasmsGastroesophageal Junction+1 more
Merck Sharp & Dohme LLC160 enrolled50 locationsNCT06469944
Recruiting
Phase 1Phase 2
Lead-212 PSV359 Therapy for Patients With Solid Tumors
Esophageal CancerGastric CancerPancreatic Ductal Adenocarcinoma
Perspective Therapeutics112 enrolled7 locationsNCT06710756
Recruiting
Phase 2
Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric Cancer
Stage IV Esophageal Cancer AJCC v7Stage IV Gastric Cancer AJCC v7Gastric Adenocarcinoma+2 more
M.D. Anderson Cancer Center100 enrolled1 locationNCT03161522
Recruiting
Phase 2
A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
Breast CancerEsophageal CancerGastric Cancer+1 more
Jazz Pharmaceuticals200 enrolled21 locationsNCT06695845
Recruiting
Phase 2
HEARTS Trial for Thoracic Cancers
Non-Small Cell Lung Cancer (Stage III)Esophageal Cancer Stage I-IIIEsophagogastric Cancer Stage I-III+2 more
University of Wisconsin, Madison60 enrolled1 locationNCT07132918
Recruiting
Phase 2
A Study of Bemosubaiabimab Combined With Anlotinib and Radiotherapy and Chemotherapy for the Treatment of Oligometastatic Esophageal Cancer
Esophageal Cancer
The First Affiliated Hospital with Nanjing Medical University28 enrolled1 locationNCT07455019
Recruiting
Phase 1Phase 2
Clinical Trial Evaluating TQB6411 Injection in Subjects With Esophageal Cancer
Esophageal Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.105 enrolled30 locationsNCT07367516
Recruiting
Phase 2
Induction Immunochemotherapy Followed by Concurrent Chemoradiotherapy in Patients With ESCC.
Esophageal Cancer
Tianjin Medical University Cancer Institute and Hospital60 enrolled1 locationNCT06452602
Recruiting
Phase 2
Study of Tislelizumab Combined With Chemoradiotherapy and Surgery for Unresectable Esophageal Squamous Cell Carcinoma
Esophageal Squamous Cell Carcinoma (ESCC)Locally Advanced Unresectable Esophageal Cancer
Ming-Yu Lien45 enrolled8 locationsNCT07039162
Recruiting
Phase 2Phase 3
Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy
EsophagectomyEsophageal Cancer SurgeryDelayed Gastric Emptying Following Procedure+4 more
The Cleveland Clinic170 enrolled1 locationNCT06721520
Recruiting
Phase 2
DCRT vs. Surgery in Resectable ESCC Patient Achiving cCR/PR After nCI
Esophageal Cancer
Tianjin Medical University Cancer Institute and Hospital120 enrolled1 locationNCT07162506
Recruiting
Phase 2
A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer
Esophageal CancerGastric AdenocarcinomaHER2 Gene Mutation
Memorial Sloan Kettering Cancer Center49 enrolled10 locationsNCT06123338
Recruiting
Phase 2
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Breast CancerEsophageal CancerGastric Cancer+11 more
Daiichi Sankyo740 enrolled84 locationsNCT06172478
Recruiting
Phase 2
Radiotherapy Combined With Immunochemotherapy in Metastatic Esophageal Squamous Cell Carcinoma
Esophageal CancerEsophageal Squamous Cell CarcinomaMetastatic Esophageal Squamous Cell Carcinoma
Shanghai Chest Hospital100 enrolled2 locationsNCT05978193
Recruiting
Phase 2
A Phase II Clinical Study to Evaluate HLX43 in Patients With Recurrent/Metastatic ESCC Failed or Intolerance to Standard Therapy
Esophageal Cancer
Shanghai Henlius Biotech72 enrolled1 locationNCT06769113
Recruiting
Phase 2
Chemoradiation Plus Iparomlimab Consolidation in Older With ESCC
Esophageal Cancer
Tianjin Medical University Cancer Institute and Hospital52 enrolled1 locationNCT07038629
Recruiting
Phase 2
Total Neoadjuvant Therapy for Lymph Node-positive Adenocarcinoma of the OESophagus and Oesophagogastric Junction
Esophageal CancerAdenocarcinoma of the Esophagus
Erasmus Medical Center216 enrolled10 locationsNCT06161818
Recruiting
Phase 2
Chemoradiotherapy for Advanced Esophageal Cancer
Esophageal Cancer
AHS Cancer Control Alberta50 enrolled1 locationNCT02297217
Recruiting
Phase 1Phase 2
A Study of MT-4561 in Patients With Various Advanced Solid Tumors
Breast CancerEsophageal CancerGastric Cancer+13 more
Tanabe Pharma America, Inc.27 enrolled6 locationsNCT06943521