Phase 3 Esophageal Cancer Clinical Trials
22 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 22 trials
Recruiting
Phase 3
PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy Plus Surgery for Locally Advanced ESCC (NEOCRTEC2101)
Esophageal CancerOesophageal CancerSquamous Cell Esophageal Carcinoma
Sun Yat-sen University422 enrolled1 locationNCT05357846
Recruiting
Phase 3
Consolidation of Toripalimab and Capecitabine After Chemoradiotherapy in ESCC
Esophageal CancerChemoradiotherapy
Sun Yat-sen University242 enrolled1 locationNCT07177794
Recruiting
Phase 3
Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.
Esophageal CancerGastric Cancer (GC)Gastroesophageal Junction
SOFIE200 enrolled10 locationsNCT07217704
Recruiting
Phase 3
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2
Esophageal CancerGastric CancerGastroesophageal Junction Adenocarcinoma
AstraZeneca2,130 enrolled258 locationsNCT07431281
Recruiting
Phase 2Phase 3
Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy
EsophagectomyEsophageal Cancer SurgeryDelayed Gastric Emptying Following Procedure+4 more
The Cleveland Clinic170 enrolled1 locationNCT06721520
Recruiting
Phase 3
The Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial - Stage III
Esophageal CancerGastric CancerLung Cancer
Ottawa Hospital Research Institute20 enrolled2 locationsNCT04871412
Recruiting
Phase 3
Neoadjuvant Treatment Modalities in Esophageal Cancer
Esophageal CancerSurgeryChemotherapy Effect+4 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences2,000 enrolled1 locationNCT04821843
Recruiting
Phase 3
Study of Larotinib in Unresectable Advanced or Recurrent Esophageal Cancer
Esophageal Cancer
Sunshine Lake Pharma Co., Ltd.416 enrolled1 locationNCT04415853
Recruiting
Phase 2Phase 3
Perioperative Analgesia Modes in Minimally Invasive Esophagectomy
Esophageal CancerPerioperative AnalgesiaNSAIDs+2 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences102 enrolled1 locationNCT05504265
Recruiting
Phase 3
Perioperative SDD to Prevent Infectious Complications After Esophagectomy
Esophageal Cancer
Radboud University Medical Center854 enrolled2 locationsNCT05865743
Recruiting
Phase 2Phase 3
Multicenter Validation Trial of [18F]AlF-FAPI-74 for PET Imaging of Cancer-associated Fibroblasts Through Fibroblast Activation Protein Inhibitors (FAPI) in Different Tumor Types
Gastric CancerPancreatic Ductal AdenocarcinomaOncology+3 more
KU Leuven109 enrolled3 locationsNCT06782412
Recruiting
Phase 3
PROton Versus Photon Therapy for Esophageal Cancer - a Trimodality Strategy
Esophageal CancerProton TherapyRadiotherapy+1 more
University of Aarhus396 enrolled15 locationsNCT05055648
Recruiting
Phase 3
Total Intravenous Anesthesia and Recurrence Free Survival
Esophageal Cancer
The Cleveland Clinic1,614 enrolled1 locationNCT04513808
Recruiting
Phase 3
An Organ Preservation Strategies After Chemoradiotherapy Combined With Immunotherapy for Esophageal Cancer (PALACE3).
Esophageal Cancer
Ruijin Hospital356 enrolled1 locationNCT06339060
Recruiting
Phase 3
Neo-adjuvant Immunochemotheray Versus Neo-adjuvant Chemotherapy for Resectable Esophageal Carcinoma
Esophageal CancerSurgeryNeoadjuvant Treatment+1 more
Henan Cancer Hospital400 enrolled1 locationNCT04280822
Recruiting
Phase 3
The Efficacy of Neoadjuvant Chemoradiotherapy in Comparison With Neoadjuvant Chemotherapy in Patients With Resectable Squamous Cell Esophageal Cancer
Esophageal Cancer
Blokhin's Russian Cancer Research Center156 enrolled1 locationNCT05547529
Recruiting
Phase 3
TRAstuzumab and Pertuzumab for HER2+ Resectable Oesophageal Cancer
Esophageal CancerEsophageal Adenocarcinoma
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)376 enrolled1 locationNCT05188313
Recruiting
Phase 3
Comparison of Esophagectomy and Chemoradiation for Patients With cN0-pT1b Stage Esophageal Squamous Cell Carcinoma
Esophageal Cancer
Shanghai Chest Hospital176 enrolled6 locationsNCT04135664
Recruiting
Phase 3
Salvage Chemoradiation Therapy for Recurrence After Radical Surgery or Palliative Surgery in Esophageal Cancer Patients
Esophageal Cancer
Chinese Academy of Medical Sciences300 enrolled1 locationNCT03731442
Completed
Phase 3
Targeted thromboprophylaxis in ambulatory patients receiving anticancer therapies (TARGET-TP)
Liver CancerPancreatic CancerLung Cancer+4 more
Peter MacCallum Cancer Centre300 enrolled5 locationsACTRN12618000811202