ESS Clinical Trials in Philadelphia, Pennsylvania

87 recruitingPhiladelphia, Pennsylvania

Showing 120 of 87 trials

Recruiting
Phase 3

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder
Neurocrine Biosciences850 enrolled87 locationsNCT06966401
Recruiting
Not Applicable

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

Treatment Resistant Depression
Abbott Medical Devices100 enrolled28 locationsNCT06423430
Recruiting
Phase 2

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

Major Depressive Disorder
Syndeio Biosciences, Inc164 enrolled32 locationsNCT07115329
Recruiting
Phase 2

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Recurrent GlioblastomaProgressive Glioblastoma
National Cancer Institute (NCI)184 enrolled324 locationsNCT06325683
Recruiting
Phase 1Phase 2

Gene Therapy for HER-Positive Cancer (SENTRY-HER2)

HER2 Expressing Solid Tumors
Vironexis Biotherapeutics Inc.27 enrolled4 locationsNCT07192432
Recruiting
Phase 3

A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

Diabetes Mellitus, Type 1Impaired Hypoglycemic AwarenessSevere Hypoglycemia
Vertex Pharmaceuticals Incorporated52 enrolled29 locationsNCT04786262
Recruiting

UPenn Observational Research Repository on Neurodegenerative Disease

Primary Progressive Aphasia(PPA)Frontotemporal Degeneration(FTD)Familial Frontotemporal Lobar Degeneration (fFTLD)+2 more
University of Pennsylvania1,000 enrolled1 locationNCT04715399
Recruiting

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

Movement DisordersParkinson DiseaseDystonia+4 more
Abbott Medical Devices1,000 enrolled48 locationsNCT04071847
Recruiting
Phase 3

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

Relapsing Multiple SclerosisRelapsing Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis
National Institute of Allergy and Infectious Diseases (NIAID)156 enrolled22 locationsNCT04047628
Recruiting
Not Applicable

Taking Action for College Students

SchizophreniaMajor Depressive DisorderBipolar Disorder
Temple University300 enrolled1 locationNCT06700902
Recruiting

Surviving Daily Life

Breast CancerBreast CarcinomaBreast Neoplasm+3 more
Thomas Jefferson University30 enrolled1 locationNCT07054723
Recruiting
Not Applicable

Telehealth Collaborative Care Model (CoCM) in Lung Cancer

Lung Cancer (Diagnosis)AnxietyDepression in Adults
Abramson Cancer Center at Penn Medicine30 enrolled1 locationNCT07102147
Recruiting
Phase 2

A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients

Secondary Progressive Multiple Sclerosis
Tiziana Life Sciences LTD54 enrolled7 locationsNCT06292923
Recruiting
Phase 1

CT-95 in Advanced Cancers Associated With Mesothelin Expression

Mesothelin-Expressing TumorsEpithelial Ovarian CancerLung Adenocarcinoma Metastatic+7 more
Context Therapeutics Inc.70 enrolled8 locationsNCT06756035
Recruiting
Not Applicable

Clinical Trial for Integrated Care to Help At Risk Teen (iCHART) Intervention

Adolescent BehaviorSuicide and Depression
University of Pittsburgh900 enrolled13 locationsNCT05748730
Recruiting
Not Applicable

Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

DepressionSleepSleep Disturbance+1 more
University of Pittsburgh90 enrolled2 locationsNCT06963463
Recruiting
Phase 3

Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

Major Depressive Disorder
Intra-Cellular Therapies, Inc.470 enrolled60 locationsNCT05850689
Recruiting
Not Applicable

Improving Mood for Adolescents Through Teaming With End-Users in Routine Care (The iMATTER Project)

Depressive Symptoms
Children's Hospital of Philadelphia45 enrolled1 locationNCT07020572
Recruiting

A Registry for People With T-cell Lymphoma

T-cell LymphomaNK-Cell LymphomaT-cell Prolymphocytic Leukemia+4 more
Memorial Sloan Kettering Cancer Center1,000 enrolled26 locationsNCT05978141
Recruiting
Phase 1

Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 Inhibition

Chronic Myelomonocytic LeukemiaPolycythemia VeraPrimary Myelofibrosis+3 more
Fox Chase Cancer Center24 enrolled1 locationNCT06218628