ESS Clinical Trials in Philadelphia, Pennsylvania

102 recruitingPhiladelphia, Pennsylvania

Showing 120 of 102 trials

Recruiting
Not Applicable

Improving Mood for Adolescents Through Teaming With End-Users in Routine Care (The iMATTER Project)

Depressive Symptoms
Children's Hospital of Philadelphia45 enrolled1 locationNCT07020572
Recruiting
Phase 1

CT-95 in Advanced Cancers Associated With Mesothelin Expression

Colorectal, CancerMesothelin-Expressing TumorsEpithelial Ovarian Cancer+8 more
Context Therapeutics Inc.70 enrolled9 locationsNCT06756035
Recruiting
Phase 3

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

Non-small Cell Lung CancerAdvanced Non-Small Cell Lung CancerMetastatic Non Small Cell Lung Cancer+3 more
ArriVent BioPharma, Inc.480 enrolled74 locationsNCT07185997
Recruiting
Not Applicable

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

Treatment Resistant Depression
Abbott Medical Devices100 enrolled24 locationsNCT06423430
Recruiting
Not Applicable

Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

DepressionSleepSleep Disturbance+1 more
University of Pittsburgh90 enrolled2 locationsNCT06963463
Recruiting
Not Applicable

Telehealth Collaborative Care Model (CoCM) in Lung Cancer

Lung Cancer (Diagnosis)AnxietyDepression in Adults
Abramson Cancer Center at Penn Medicine30 enrolled1 locationNCT07102147
Recruiting
Not Applicable

BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

HypertensionHypertension, SystolicHypertension,Essential
Orchestra BioMed, Inc500 enrolled129 locationsNCT06059638
Recruiting
Phase 1Phase 2

Gene Therapy for HER-Positive Cancer (SENTRY-HER2)

HER2 Expressing Solid Tumors
Vironexis Biotherapeutics Inc.27 enrolled6 locationsNCT07192432
Recruiting

A Registry for People With T-cell Lymphoma

T-cell LymphomaNK-Cell LymphomaT-cell Prolymphocytic Leukemia+27 more
Memorial Sloan Kettering Cancer Center1,000 enrolled26 locationsNCT05978141
Recruiting
Phase 2

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Recurrent GlioblastomaProgressive Glioblastoma
National Cancer Institute (NCI)184 enrolled324 locationsNCT06325683
Recruiting
Phase 1

SynKIR-310 for Relapsed/Refractory B-NHL

Diffuse Large B Cell LymphomaHigh-grade B-cell LymphomaDLBCL - Diffuse Large B Cell Lymphoma+23 more
Verismo Therapeutics36 enrolled5 locationsNCT06544265
Recruiting
Phase 3

A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

Diabetes Mellitus, Type 1Impaired Hypoglycemic AwarenessSevere Hypoglycemia
Vertex Pharmaceuticals Incorporated52 enrolled29 locationsNCT04786262
Recruiting

UPenn Observational Research Repository on Neurodegenerative Disease

Corticobasal Syndrome(CBS)Progressive Supranuclear Palsy (PSP)Primary Progressive Aphasia(PPA)+6 more
University of Pennsylvania1,000 enrolled1 locationNCT04715399
Recruiting
Phase 1Phase 2

A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer

Small Cell Lung CancerNeuroendocrine CarcinomasSolid Tumor Show to Express DLL3
IDEAYA Biosciences208 enrolled39 locationsNCT07174583
Recruiting

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

Movement DisordersParkinson DiseaseDystonia+4 more
Abbott Medical Devices1,000 enrolled48 locationsNCT04071847
Recruiting
Phase 3

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

Relapsing Multiple SclerosisRelapsing Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis
National Institute of Allergy and Infectious Diseases (NIAID)156 enrolled22 locationsNCT04047628
Recruiting

Surviving Daily Life

Breast CancerBreast CarcinomaBreast Neoplasm+3 more
Thomas Jefferson University30 enrolled1 locationNCT07054723
Recruiting
Phase 2

A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients

Secondary Progressive Multiple Sclerosis
Tiziana Life Sciences LTD54 enrolled7 locationsNCT06292923
Recruiting
Phase 3

Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

Major Depressive Disorder
Intra-Cellular Therapies, Inc.470 enrolled60 locationsNCT05850689
Recruiting
Phase 1

Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 Inhibition

Chronic Myelomonocytic LeukemiaPolycythemia VeraPrimary Myelofibrosis+3 more
Fox Chase Cancer Center24 enrolled1 locationNCT06218628