ESS Clinical Trials in Boston, Massachusetts

192 recruitingBoston, Massachusetts

Showing 120 of 192 trials

Recruiting
Phase 1Phase 2

An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)

Progressive Metastatic Castrate Resistant Prostate Cancer
Novartis Pharmaceuticals188 enrolled29 locationsNCT07206056
Recruiting
Phase 2

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Advanced Systemic Mastocytosis (AdvSM)SM With an Associated Hematologic Neoplasm (SM-AHN)Mast Cell Leukemia (MCL)+1 more
Cogent Biosciences, Inc.140 enrolled42 locationsNCT04996875
Recruiting
Phase 3

PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.

Prostate CancerAndrogen Axis SuppressionProstatectomy
M.D. Anderson Cancer Center120 enrolled3 locationsNCT06274047
Recruiting
Not Applicable

ACT Lung Health Intervention: Phase Two

Smoking CessationSmoking BehaviorsSmoking, Tobacco+2 more
Dana-Farber Cancer Institute50 enrolled2 locationsNCT06945120
Recruiting
Phase 2

Palbociclib and Pembrolizumab In Central Nervous System Metastases

Metastatic Malignant Neoplasm to BrainRecurrent Brain MetastasesProgressive Brain Metastases
Massachusetts General Hospital45 enrolled2 locationsNCT02896335
Recruiting
Not Applicable

Practical Geriatric Assessment in Older Adults With Non-Small Cell Lung Cancer Undergoing Stereotactic Body Radiation Therapy

Lung Cancer (NSCLC)Geriatric AssessmentStereotactic Body Radiation Therapy (SBRT)
Brigham and Women's Hospital64 enrolled1 locationNCT06987890
Recruiting
Not Applicable

Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens

Lung CancerLymph Node MetastasisPathologic Processes
Brigham and Women's Hospital160 enrolled1 locationNCT06252129
Recruiting
Not Applicable

Targeted Accelerated TMS for Post-Traumatic Stress Disorder

Post Traumatic Stress Disorder (PTSD)
Brigham and Women's Hospital40 enrolled1 locationNCT07245641
Recruiting
Phase 2

A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors

Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal CancerPart 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer
AstraZeneca468 enrolled123 locationsNCT04482309
Recruiting
Phase 1

A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies

Chronic Myeloid LeukemiaMyelodysplastic SyndromesClassical Hodgkin Lymphoma+5 more
MacroGenics130 enrolled7 locationsNCT05362773
Recruiting

The CurePSP Genetics Program

PSPPSP - Progressive Supranuclear PalsyCorticobasal Syndrome+4 more
Massachusetts General Hospital1,000 enrolled1 locationNCT06647641
Recruiting
Not Applicable

Building Connections

ObesityDepression, AnxietyCancer Cervix+1 more
Massachusetts General Hospital3,600 enrolled1 locationNCT07091032
Recruiting
Not Applicable

Stereotactic Magnetic Resonance Guided Radiation Therapy

Prostate CancerLung CancerSpine Metastases+10 more
Dana-Farber Cancer Institute397 enrolled2 locationsNCT04115254
Recruiting

Safety Study to Evaluate the Occurrence of EFAD in Pediatric Patients With PNAC Who Require More Than Eight Weeks of Omegaven Treatment

Pediatric ALLMalnutritionParenteral Nutrition Associated Liver Disease (PNALD)+1 more
Fresenius Kabi40 enrolled10 locationsNCT06274788
Recruiting

Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients

Pain, ChronicPain, PostoperativeSensation Disorders+6 more
Weill Medical College of Cornell University400 enrolled2 locationsNCT06094257
Recruiting
Phase 1Phase 2

Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia

Chronic Myelomonocytic LeukemiaMyelodysplastic Syndrome With Excess Blasts-2Leukemia, Myeloid, Acute+2 more
Aptose Biosciences Inc.240 enrolled34 locationsNCT03850574
Recruiting
Phase 1

BXCL701 Phase 1 R/R Acute Myeloid Leukemia or Myelodysplastic Syndrome

Acute Myeloid LeukemiaMyelodysplastic Syndrome With Excess Blasts-2
Eric Stephen Winer, MD24 enrolled1 locationNCT05703542
Recruiting
Not Applicable

ASCENT Intervention for Brain Tumor Patients

Distress, EmotionalGliomaMalignant Brain Tumor+1 more
Massachusetts General Hospital100 enrolled1 locationNCT06099743
Recruiting
Not Applicable

Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

ObesityPregnancyDepression+4 more
Massachusetts General Hospital1,320 enrolled1 locationNCT06557005
Recruiting

A Registry for People With T-cell Lymphoma

T-cell LymphomaNK-Cell LymphomaT-cell Prolymphocytic Leukemia+4 more
Memorial Sloan Kettering Cancer Center1,000 enrolled26 locationsNCT05978141