Phase 2 Estrogen Clinical Trials
17 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–17 of 17 trials
Recruiting
Phase 2
Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial
Breast CarcinomaEstrogen Receptor-Positive Breast CarcinomaBreast Ductal Carcinoma in Situ+3 more
National Cancer Institute (NCI)200 enrolled11 locationsNCT06184750
Recruiting
Phase 2
Reishi Mushroom Extract for Fatigue and/or Arthralgias/Myalgias in Patients With Breast Cancer on Aromatase Inhibitors
Estrogen Receptor-Positive Breast Carcinoma
Mayo Clinic80 enrolled23 locationsNCT06028022
Recruiting
Phase 2
PhII Randomized CAPecitabine + ELAcestrant vs. Capecitabine Alone in ER+ Breast Cancer (CAPELA)
Breast CancerMetastatic Breast CancerBreast Neoplasms+6 more
Kristina A. Fanucci297 enrolled1 locationNCT07222215
Recruiting
Phase 2
Ph 2 Elacestrant in ER Positive Uterine Sarcomas
Estrogen Receptor Positive TumorEndometrial Stromal SarcomaUterine Sarcoma+6 more
Dana-Farber Cancer Institute30 enrolled1 locationNCT07467772
Recruiting
Phase 2
Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies
Breast CancerTriple-Negative Breast CancerMetastatic Breast Cancer+2 more
UNC Lineberger Comprehensive Cancer Center700 enrolled2 locationsNCT07340541
Recruiting
Phase 2
Adaptive Therapy With Capecitabine for Treatment of Metastatic ER Positive, HER2 Negative Breast Cancer
Metastatic Breast CancerAnatomic Stage IV Breast Cancer AJCC v8Estrogen Receptor-positive Breast Cancer+1 more
Mayo Clinic35 enrolled1 locationNCT06525766
Recruiting
Phase 2
SOC Chemotherapy +/- Tocilizumab for Triple Negative and ER-low Breast Cancers
Triple-Negative Breast CancerMetastatic Breast CancerEstrogen-receptor-low Breast Cancer
Kathy Miller168 enrolled6 locationsNCT05846789
Recruiting
Phase 2
High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced Arthralgia in Women With Breast Cancer
Estrogen Receptor-Positive Breast CarcinomaAnatomic Stage II Breast Cancer AJCC v8Anatomic Stage 0 Breast Cancer AJCC v8+5 more
City of Hope Medical Center36 enrolled1 locationNCT06538389
Recruiting
Phase 2
Turkey Tail Mushroom for Treating Post-Menopausal Women With HER2-Negative ER-Positive Breast Cancer Undergoing Surgery
Estrogen Receptor-Positive Breast CarcinomaHER2-Negative Breast Carcinoma
Mayo Clinic40 enrolled1 locationNCT06450873
Recruiting
Phase 2
(Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer
Breast NeoplasmsHER2-negative Breast CancerInvasive Breast Cancer+1 more
Atossa Therapeutics, Inc.87 enrolled15 locationsNCT05607004
Recruiting
Phase 2
Elacestrant vs Elacestrant Plus a CDK4/6 Inhibitor in Patients With ERpositive/HER2-negative Advanced or Metastatic Breast Cancer
Metastatic Breast CancerEstrogen Receptor-positive Breast CancerHER2/Neu-Negative Breast Cancer+1 more
Northwestern University174 enrolled1 locationNCT06062498
Recruiting
Phase 2
Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer
Estrogen Receptor-Positive Breast CarcinomaAnatomic Stage IV Breast Cancer AJCC v8Metastatic Breast Carcinoma
City of Hope Medical Center18 enrolled2 locationsNCT06260033
Recruiting
Phase 2
The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer
Breast CancerBreast Cancer MetastaticBreast Cancer Female+3 more
Dana-Farber Cancer Institute72 enrolled1 locationNCT06439693
Recruiting
Phase 2
Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt)
Estrogen Receptor-positive Breast CancerEarly Stage Breast Cancer
Jules Bordet Institute112 enrolled1 locationNCT06150898
Recruiting
Phase 2
The Role of Estrogen in the Neurobiology of Eating Disorders
Eating DisordersHypoestrogenemia
Massachusetts General Hospital120 enrolled1 locationNCT03740204
Recruiting
Phase 2
Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer
Breast CancerTriple-Negative Breast CancerBreast Cancer Female+8 more
Baylor Breast Care Center185 enrolled2 locationsNCT05020860
Recruiting
Phase 2
Pembrolizumab and Carboplatin in Treating Patients With Circulating Tumor Cells Positive Metastatic Breast Cancer
Triple-Negative Breast CarcinomaRecurrent Breast CarcinomaStage IV Breast Cancer+4 more
Northwestern University100 enrolled1 locationNCT03213041