FAP Clinical Trials

9 recruiting

FAP Trials at a Glance

25 actively recruiting trials for fap are listed on ClinicalTrialsFinder across 6 cities in 30 countries. The largest study group is Early Phase 1 with 4 trials, with the heaviest enrollment activity in Chongqing, Tianjin, and Barcelona. Lead sponsors running fap studies include Peking Union Medical College Hospital, Tianjin Medical University, and Daping Hospital and the Research Institute of Surgery of the Third Military Medical University.

Browse fap trials by phase

Treatments under study

About FAP Clinical Trials

Looking for clinical trials for FAP? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new FAP trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about FAP clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 25 trials

Recruiting

Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders

Obstructive Sleep ApneaTonsillitisPeriodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis (Pfapa)+1 more
National Institute of Allergy and Infectious Diseases (NIAID)1,500 enrolled3 locationsNCT05656365
Recruiting
Phase 3

Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

Familial Adenomatous Polyposis (FAP)
Rapamycin Holdings Inc.168 enrolled26 locationsNCT06950385
Recruiting
Phase 1

A Study to Evaluate the Safety and Preliminary Signs of Efficacy of [177Lu]Lu-OncoFAP-23 Alone or in Combination With L19-IL2 as a Treatment of Metastatic FAP-positive Solid Tumors

FAP
Philogen S.p.A.56 enrolled4 locationsNCT06640413
Recruiting
Not Applicable

Pain in Pediatric Patients - Internet Interventions for Disorders of Gut-brain Interaction

Functional DyspepsiaIrritable Bowel DiseaseFunctional Abdominal Pain - Not Otherwise Specified (FAP-NOS)
Karolinska Institutet200 enrolled1 locationNCT07319078
Recruiting

Analysis of NfL and GFAP in Different Dietary Patterns

GFAPVegan DietNeurofilament Light Chain+2 more
Salzburger Landeskliniken300 enrolled1 locationNCT07312994
Recruiting

Duodenal Polyposis Classification in FAP

Familial Adenomatous PolyposisFAPDuodenal Neoplasms+6 more
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano300 enrolled2 locationsNCT07199127
Recruiting
Not Applicable

Investigation of β-hydroxybutyrate Supplementation as Chemoprevention in Familial Adenomatous Polyposis

Familial Adenomatous PolyposisFAP
Abramson Cancer Center at Penn Medicine20 enrolled1 locationNCT06578637
Recruiting

Medium-term Effects of Treatments in Autoimmune Encephalitis

GFAPNMDAR Autoimmune EncephalitisLGI1 Antibody Associated Encephalitis+3 more
Hospices Civils de Lyon200 enrolled1 locationNCT07133113
Recruiting

Prostate Specific Membrane Antigen PET/CT Imaging in PSMA-Related Disease Patients

Prostate CancerMetastasisPositron Emission Tomography+2 more
Tianjin Medical University500 enrolled2 locationsNCT06690970
Recruiting
Not Applicable

68Ga-FAPI-LM3 PET/CT Imaging in Patients With FAP/SSTR2 Positive Disease and Compared With 18F-FDG

FAPSSTR2
The First Affiliated Hospital of Xiamen University30 enrolled1 locationNCT05873777
Recruiting

Multimodal Imaging Assessment of Chronic Kidney Disease Patients at Different Stages From a Cardio-Renal Interaction Perspective

Chronic Kidney DiseaseCardiac Magnetic Resonance18F-FAPI
The Affiliated Hospital of Qingdao University60 enrolled1 locationNCT07107919
Recruiting
Phase 2Phase 3

Pancreatic Cancer Diagnosis With FAPI-PET Imaging

Pancreatic CancerFAPIPositron Emission Tomography+5 more
Turku University Hospital100 enrolled1 locationNCT07098598
Recruiting

AutoInflammatory Disease Alliance Registry (AIDA)

UveitisStill DiseaseHereditary Autoinflammatory Diseases+5 more
University of Siena3,500 enrolled112 locationsNCT05200715
Recruiting
Phase 2

The Diagnostic Accuracy and Clinical Value of FAPI PET in Pleural Mesothelioma

CancerPleural MesotheliomaPleural Diseases+2 more
Aalborg University Hospital70 enrolled1 locationNCT06790082
Recruiting

Evaluation of Intestinal Lesions and Disease Activity in Inflammatory Bowel Disease Based on 18F-FAPI PET Imaging

FAPIInflammatory Bowel Disease (IBD)Disease Activity
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University30 enrolled1 locationNCT06945549
Recruiting
Early Phase 1

68Ga-PSFA PET Imaging in Patients With PSMA/FAP Positive Disease

FAPPSMA
First Affiliated Hospital of Chongqing Medical University30 enrolled1 locationNCT06387381
Recruiting

Exploring the Application Value of PET Molecular Imaging Targeting FAP in Oral Squamous Cell Carcinoma

PET/CTOral CancerFAPI
Zhongnan Hospital100 enrolled1 locationNCT05030597
Recruiting

FAPI PET/CT in Various FAP-Related Disease Patients

MetastasisTumorPositron Emission Tomography+1 more
Tianjin Medical University500 enrolled1 locationNCT06688071
Recruiting
Phase 2Phase 3

Multicenter Validation Trial of [18F]AlF-FAPI-74 for PET Imaging of Cancer-associated Fibroblasts Through Fibroblast Activation Protein Inhibitors (FAPI) in Different Tumor Types

Gastric CancerPancreatic Ductal AdenocarcinomaOncology+3 more
KU Leuven109 enrolled3 locationsNCT06782412
Recruiting
Not Applicable

Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults

DementiaCognitive DysfunctionCognitive Decline+8 more
Universidade Federal do Rio de Janeiro40 enrolled1 locationNCT06733714