gastrointestinal Clinical Trials in Boston, Massachusetts

22 recruitingBoston, Massachusetts

Showing 120 of 22 trials

Recruiting
Phase 2

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

Pancreatic Neuroendocrine TumorVon Hippel-Lindau DiseasePheochromocytoma/Paraganglioma+2 more
Merck Sharp & Dohme LLC322 enrolled84 locationsNCT04924075
Recruiting
Phase 1Phase 2

COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER

Colorectal, CancerStenosisFibrosis, Liver+4 more
Massachusetts General Hospital80 enrolled1 locationNCT05692024
Recruiting
Phase 1

First-in-human Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors

Metastatic CancerGastrointestinal NeoplasmsGastrointestinal Diseases+2 more
IDRX, Inc., a wholly owned subsidiary of GSK, LLC278 enrolled31 locationsNCT05489237
Recruiting
Not Applicable

BOLSTER: Learning New Skills to Thrive

Advanced CancerGynecologic CancerGastrointestinal Cancer
Dana-Farber Cancer Institute600 enrolled2 locationsNCT06936878
Recruiting

Gastroparesis Registry 4

Gastro-Intestinal DisorderGastroparesisGastroparesis Nondiabetic+3 more
Johns Hopkins Bloomberg School of Public Health250 enrolled6 locationsNCT05846802
Recruiting
Phase 3

A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

Gastrointestinal Neoplasms
GlaxoSmithKline450 enrolled84 locationsNCT07218926
Recruiting
Phase 1Phase 2

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

Colorectal, CancerPancreatic Ductal AdenocarcinomaMetastatic Pancreatic Ductal Adenocarcinoma+3 more
Revolution Medicines, Inc.1,130 enrolled32 locationsNCT06445062
Recruiting
Phase 1

A Study Evaluating Anvumetostat in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion (MTAPESTRY 103)

Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
Amgen350 enrolled77 locationsNCT06360354
Recruiting
Not Applicable

Resilience and Equity in Aging, Cancer, and Health (REACH)

Esophageal CancerPancreatic CancerGastric Cancer+3 more
Dana-Farber Cancer Institute257 enrolled1 locationNCT04674267
Recruiting
Not Applicable

Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections

Postoperative ComplicationsAnastomotic LeaksAnastomotic Complication+8 more
Medtronic - MITG137 enrolled8 locationsNCT07351071
Recruiting
Not Applicable

Trans-nasal Endoscopy for Bariatric Patients

ObesityGastrointestinal DiseasesObese+2 more
Christopher C. Thompson, MD, MSc100 enrolled1 locationNCT06200961
Recruiting
Not Applicable

H. Pylori Eradication With Argon Plasma During Endoscopy

Helicobacter Pylori InfectionHelicobacter PyloriH.Pylori Infection+2 more
Christopher C. Thompson, MD, MSc20 enrolled1 locationNCT06529159
Recruiting
Phase 1

A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

Gastrointestinal Stromal Tumor (GIST)Gastrointestinal Stromal NeoplasmGastrointestinal Stromal Cancer+2 more
Kura Oncology, Inc.157 enrolled32 locationsNCT06655246
Recruiting
Phase 1Phase 2

A Master Protocol to Evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST)

Gastrointestinal Stromal Tumor (GIST)
Deciphera Pharmaceuticals, LLC120 enrolled10 locationsNCT06630234
Recruiting
Not Applicable

SURGE: Supporting UnderRepresented Minorities in Genomics-based Cancer Trial Enrollment (Intervention)

Thoracic CancerGastrointestinal CancerHematologic Cancer
Nadine McCleary, MD, MPH210 enrolled3 locationsNCT05375643
Recruiting
Not Applicable

Randomized Trial of UI-EWD vs. Conventional Endoscopic Therapy for Nonvariceal Upper Gastrointestinal Bleeding

Acute Gastrointestinal Bleeding
Medtronic - MITG278 enrolled15 locationsNCT06188585
Recruiting

OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages

eosinophilic esophagitisEosinophilic GastritisEosinophilic Gastrointestinal Disorders (EGIDs)+2 more
Children's Hospital Medical Center, Cincinnati1,350 enrolled19 locationsNCT02523118
Recruiting

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

Gastrointestinal BleedingTelangiectasiaArteriovenous Malformations+4 more
Cure HHT10,000 enrolled16 locationsNCT06259292
Recruiting

A Registry for People With T-cell Lymphoma

T-cell LymphomaNK-Cell LymphomaT-cell Prolymphocytic Leukemia+27 more
Memorial Sloan Kettering Cancer Center1,000 enrolled26 locationsNCT05978141
Recruiting
Not Applicable

Immune Responses to Gluten

Celiac DiseaseCeliac Disease in ChildrenIntestinal Disease+4 more
Boston Children's Hospital400 enrolled2 locationsNCT05209568