Generalized Anxiety Clinical Trials

8 recruiting

Generalized Anxiety Trials at a Glance

60 actively recruiting trials for generalized anxiety are listed on ClinicalTrialsFinder across 6 cities in 23 countries. The largest study group is Not Applicable with 37 trials, with the heaviest enrollment activity in Boston, Austin, and Dallas. Lead sponsors running generalized anxiety studies include Karolinska Institutet, Beijing Union Pharmaceutical Factory Ltd, and Baylor College of Medicine.

Browse generalized anxiety trials by phase

Treatments under study

About Generalized Anxiety Clinical Trials

Looking for clinical trials for Generalized Anxiety? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Generalized Anxiety trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Generalized Anxiety clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 60 trials

Recruiting
Not Applicable

Text Message Safety Behavior Fading for Pathological Worry

WorryingAnxietyGeneralized Anxiety Disorder (GAD)
Florida State University300 enrolled1 locationNCT07391020
Recruiting
Not Applicable

Enhancing Health in Rural Populations: Music as Therapy

StressChronic PainDepression Disorder+1 more
Northern Arizona University60 enrolled2 locationsNCT07538427
Recruiting

Validation of a Rapid Screening Tool for Anxiety-depressive Disorders in Children, Adolescents and Young Adults Treated in Oncology. Multicenter Study.

Depression, AnxietySurvivors of Childhood CancerGeneralized Anxiety+1 more
Centre Hospitalier Universitaire de Saint Etienne545 enrolled7 locationsNCT07117058
Recruiting
Not Applicable

Transdiagnostic Metacognitive Therapy Compared to Disorder-Specific Cognitive-Behavioral Therapy for Anxiety Disorders

Posttraumatic Stress Disorder (PTSD)Generalized Anxiety Disorder (GAD)Social Anxiety Disorder (SAD)
Karolinska Institutet86 enrolled1 locationNCT06937892
Recruiting
Phase 3

A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)

Generalized Anxiety Disorder
Definium Therapeutics US, Inc.250 enrolled38 locationsNCT06809595
Recruiting

LHC-CIDI-5 in Hong Kong

Suicidal IdeationMajor Depressive Disorder (MDD)Bipolar I Disorder+14 more
The University of Hong Kong2,500 enrolled1 locationNCT06804525
Recruiting
Phase 3

Cannabidiol-Assisted Learning for Managing Generalized Anxiety Disorder

Anxiety DisordersGeneralized Anxiety Disorder (GAD)
Wayne State University90 enrolled1 locationNCT07123467
Recruiting
Not Applicable

Stepped Care Treatment for Anxiety Resilience

Obsessive Compulsive Disorder (OCD)Specific PhobiaGeneralized Anxiety Disorder (GAD)+3 more
Andrew Wiese106 enrolled1 locationNCT07228143
Recruiting
Not Applicable

Stepped Versus Stratified Care for Anxiety Disorders in Youth

Social Anxiety DisorderGeneralized Anxiety DisorderSpecific Phobia+3 more
Region Skane556 enrolled1 locationNCT06942429
Recruiting
Phase 3

A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Voyage)

Generalized Anxiety Disorder
Definium Therapeutics US, Inc.200 enrolled36 locationsNCT06741228
Recruiting
Not Applicable

Internet-Delivered Cognitive Behavioral Intervention for Youths With Anxiety Disorders

Social Anxiety DisorderGeneralized Anxiety DisorderSpecific Phobia+4 more
Lund University48 enrolled1 locationNCT06661460
Recruiting
Not Applicable

Transcranial Alternating Current Stimulation for Generalized Anxiety Disorder and Insomnia: An Open-Label Pilot Study

Chronic InsomniaGeneralized Anxiety Disorder (GAD)
University of Sao Paulo30 enrolled1 locationNCT07429578
Recruiting
Not Applicable

CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy

Post Traumatic Stress DisorderObsessive-Compulsive DisorderSocial Anxiety Disorder+2 more
University of Texas at Austin600 enrolled2 locationsNCT05467683
Recruiting
Phase 2

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

Depression, AnxietySchizophreniaPsychiatric Disorder+5 more
Brigham and Women's Hospital180 enrolled2 locationsNCT06376734
Recruiting
Not Applicable

Low-Intensity Focused Ultrasound Pulsation (LIFUP) for the Treatment of Generalized Anxiety Disorder (GAD)

Generalized Anxiety Disorder
University of California, Los Angeles48 enrolled3 locationsNCT04557891
Recruiting
Not Applicable

MBSR Mechanisms in GAD

Generalized Anxiety Disorder
NYU Langone Health150 enrolled1 locationNCT05064813
Recruiting
Phase 2

Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder

Generalized Anxiety Disorder (GAD)
AbbVie315 enrolled52 locationsNCT06846320
Recruiting
Phase 2

Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder

Generalized Anxiety Disorder
Intra-Cellular Therapies, Inc.705 enrolled69 locationsNCT06480383
Recruiting
Phase 2

Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder

Generalized Anxiety Disorder
Intra-Cellular Therapies, Inc.570 enrolled60 locationsNCT06701903
Recruiting
Phase 2

Prospective Clinical Trial of Crisugabalin Capsules in the Treatment of Generalized Anxiety Disorder

Generalized Anxiety Disorder
Anhui Medical University216 enrolled1 locationNCT07330648