Depression, Anxiety Clinical Trials

55 recruiting

Depression, Anxiety Trials at a Glance

55 actively recruiting trials for depression, anxiety are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Not Applicable with 35 trials, with the heaviest enrollment activity in Boston, Ottawa, and Madison. Lead sponsors running depression, anxiety studies include Massachusetts General Hospital, Ottawa Hospital Research Institute, and The Hong Kong Polytechnic University.

Browse depression, anxiety trials by phase

Treatments under study

About Depression, Anxiety Clinical Trials

Looking for clinical trials for Depression, Anxiety? There are currently 55 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Depression, Anxiety trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Depression, Anxiety clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 55 trials

Recruiting
Not Applicable

Weekly Dynamics of Psychopathological and Symptom Networks During Mindfulness-Based Interventions for Emotional Distress

Depression, AnxietyEmotional Disorders
Peking University500 enrolled1 locationNCT07280481
Recruiting
Not Applicable

Promoting Mental Health of Teachers and Caregiver Using a Personalized mHealth Toolkit in Uganda

Depression, AnxietyMental Health Literacy
NYU Langone Health1,180 enrolled2 locationsNCT06087159
Recruiting
Phase 2

Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy

Advanced CancerDepression, AnxietyPsilocybin-Assisted Psychotherapy
M.D. Anderson Cancer Center30 enrolled1 locationNCT06200155
Recruiting
Phase 1Phase 2

Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease

Quality of LifeDepression, AnxietyStress Reaction+1 more
Children's Hospital Los Angeles66 enrolled1 locationNCT05685368
Recruiting
Not Applicable

Youth Emotional and Behavioral Treatment Study

Depression, Anxiety
Florida State University500 enrolled1 locationNCT07296939
Recruiting
Not Applicable

Adaptation of an Intervention Addressing Barriers to PrEP Use Among Pregnant Women in Zimbabwe

Depression, AnxietyHIV InfectionsPregnancy Related
Massachusetts General Hospital132 enrolled1 locationNCT06226155
Recruiting
Not Applicable

intErnet-based iNterventions FOR Cardiac arrEst suRvivors

Quality of LifeSexual DysfunctionDepression, Anxiety+3 more
Azienda Usl di Bologna106 enrolled2 locationsNCT06395558
Recruiting

Validation of a Rapid Screening Tool for Anxiety-depressive Disorders in Children, Adolescents and Young Adults Treated in Oncology. Multicenter Study.

Depression, AnxietySurvivors of Childhood CancerGeneralized Anxiety+1 more
Centre Hospitalier Universitaire de Saint Etienne545 enrolled7 locationsNCT07117058
Recruiting
Not Applicable

The COMParing App Support Strategies Study

Depression, Anxiety
University of Wisconsin, Madison688 enrolled1 locationNCT07278466
Recruiting
Not Applicable

Technology-assisted Methods to Advance Suicide Prevention Among Youth in Colombia

Depression, AnxietyWell-beingSuicidal Ideations+1 more
Brown University228 enrolled1 locationNCT06651554
Recruiting
Not Applicable

Pilot Effectiveness Trial of an ACT Self-help Workbook Tailored Specifically for Prisons

Depression, AnxietyDepressionAnxiety+1 more
University of Wisconsin, Madison96 enrolled1 locationNCT06162624
Recruiting
Phase 2

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

Depression, AnxietySchizophreniaPsychiatric Disorder+5 more
Brigham and Women's Hospital180 enrolled2 locationsNCT06376734
Recruiting
Phase 2

Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder

Depression, AnxietyStressBipolar I Disorder
Mclean Hospital40 enrolled1 locationNCT05837104
Recruiting
Not Applicable

Training in Evidence-based Treatments in Psycho-Oncology

PainDepression, AnxietyDistress, Emotional+2 more
Massachusetts General Hospital115 enrolled1 locationNCT05674357
Recruiting
Not Applicable

Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics

Depression, AnxietyAntenatal DepressionPostnatal Depression
Kenyatta National Hospital2,970 enrolled2 locationsNCT06456307
Recruiting

Predictors and Process Moderators of EMDR Therapy for Depressive Symptoms

Depression, AnxietyPost-traumatic Stress SymptomsDissociation+1 more
University of Turin, Italy40 enrolled1 locationNCT07033741
Recruiting
Not Applicable

Test of Target Engagement of Ambiguity Aversion

Depression, AnxietyAnxietyIntolerance of Uncertainty+1 more
Northwestern University140 enrolled1 locationNCT06962527
Recruiting
Not Applicable

Building Connections

ObesityDepression, AnxietyCancer Cervix+1 more
Massachusetts General Hospital3,600 enrolled1 locationNCT07091032
Recruiting

Observations of a Brief Online Psychological Intervention Among People Seeking Online Mental Health Services

Depression, Anxiety
University of Regina50 enrolled1 locationNCT06178328
Recruiting
Early Phase 1

Integrating Inuit Knowledge Principles in Multi-Level Mental Health Clinical Trials

Depression, Anxiety
University of Alberta40 enrolled2 locationsNCT07014852