Phase 2 Gland Clinical Trials
26 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 26 trials
Recruiting
Phase 2
PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma
Colorectal, CancerCholangiocarcinomaColorectal Neoplasms+10 more
National Cancer Institute (NCI)70 enrolled1 locationNCT05286814
Recruiting
Phase 2
A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
Breast CancerColorectal, CancerEsophageal Cancer+9 more
Jazz Pharmaceuticals200 enrolled28 locationsNCT06695845
Recruiting
Phase 2
XL092 for the Treatment of Locally Advanced or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer
Stage III Differentiated Thyroid Gland Carcinoma AJCC v8Refractory Differentiated Thyroid Gland CarcinomaLocally Advanced Differentiated Thyroid Gland Carcinoma+18 more
Northwestern University33 enrolled2 locationsNCT06959641
Recruiting
Phase 2
Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers
Metastatic Salivary Gland CarcinomaStage III Major Salivary Gland Cancer AJCC v8Stage IV Major Salivary Gland Cancer AJCC v8+2 more
NRG Oncology146 enrolled150 locationsNCT05408845
Recruiting
Phase 2
Agnostic Therapy in Rare Solid Tumors
Cancer of Unknown PrimarySoft Tissue SarcomaCholangiocarcinoma+38 more
Instituto do Cancer do Estado de São Paulo28 enrolled8 locationsNCT06638931
Recruiting
Phase 2
Customized 3D Printed Oral Stents During Head and Neck Radiotherapy
Head and Neck CarcinomaOral Cavity CarcinomaMalignant Parotid Gland Neoplasm+4 more
M.D. Anderson Cancer Center119 enrolled7 locationsNCT04870762
Recruiting
Phase 2
Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas
Salivary Gland CancerHER2 Gene Mutation
Dana-Farber Cancer Institute37 enrolled13 locationsNCT04620187
Recruiting
Phase 2
Precision Treatment of Recurrent/Metastatic Salivary Gland Carcinoma Guided by Molecular Typing
Salivary Gland CarcinomaPrecision Therapy
Peking Union Medical College39 enrolled2 locationsNCT06145308
Recruiting
Phase 2
The Safety and Efficacy of MRG003 With or Without Putrelimab in Recurrent or Metastatic Salivary Gland Cancer: a Single-center, Open-label Cohort Study
Salivary Gland Carcinomas
Ji Dongmei90 enrolled1 locationNCT07464366
Recruiting
Phase 2
Phase II Trial of Sacituzumab Govitecan in Recurrent and/or Metastatic Secretory Gland Cancers
Salivary Gland CancersGland
M.D. Anderson Cancer Center30 enrolled1 locationNCT05884320
Recruiting
Phase 2
Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study
Head and Neck CarcinomaSalivary Gland CarcinomaMetastatic Malignant Neoplasm in the Lymph Nodes+9 more
Mayo Clinic174 enrolled9 locationsNCT05075980
Recruiting
Phase 2
A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia
Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands
MeiraGTx, LLC276 enrolled33 locationsNCT05926765
Recruiting
Phase 2
Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation
Thyroid Gland Follicular CarcinomaThyroid Gland Oncocytic CarcinomaThyroid Gland Papillary Carcinoma
City of Hope Medical Center21 enrolled1 locationNCT06440850
Recruiting
Phase 2
Androgen Deprivation Therapy (ADT) and Pembrolizumab for Advanced Stage Androgen Receptor-positive Salivary Gland Carcinoma
Salivary Gland Carcinoma
Manish Patel20 enrolled7 locationsNCT03942653
Recruiting
Phase 1Phase 2
VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
Esophageal CancerPancreatic CancerHead and Neck Squamous Cell Carcinoma (HNSCC)+22 more
VM Oncology, LLC242 enrolled15 locationsNCT03556228
Recruiting
Phase 2Phase 3
DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations
Ovarian NeoplasmsColorectal NeoplasmsUrinary Bladder Neoplasm+8 more
Cancer Research UK30 enrolled27 locationsNCT05786716
Recruiting
Phase 2
Adjuvant Rezvilutamide in Combination With Androgen Deprivation Therapy in Androgen Receptor-positive, High-risk Salivary Duct Carcinoma
Salivary Gland Neoplasm Duct
Peking University First Hospital37 enrolled2 locationsNCT06348264
Recruiting
Phase 2
A Phase 2 Trial of Ivonescimab for Patients With Advanced, Metastatic Salivary Gland Cancers
Salivary Gland CancerAdvanced Salivary Gland CarcinomaAdenoid Cystic Carcinoma+1 more
Glenn J. Hanna35 enrolled2 locationsNCT06805617
Recruiting
Phase 2
Sacituzumab Govitecan in Metastatic Salivary Gland and Thyroid Cancers (SG-SGTC)
Thyroid CancerSalivary Gland Cancer
National University Hospital, Singapore32 enrolled1 locationNCT06923826
Recruiting
Phase 2
Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC
Thyroid CancerThyroid CarcinomaPapillary Thyroid Cancer+3 more
Massachusetts General Hospital30 enrolled6 locationsNCT05668962