Glioblastoma Clinical Trials in Durham, North Carolina
15 recruitingDurham, North Carolina
Showing 1–15 of 15 trials
Recruiting
Phase 3
EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma
Glioblastoma
NovoCure GmbH741 enrolled82 locationsNCT06556563
Recruiting
Early Phase 1
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
GlioblastomaGlioblastoma MultiformeHigh Grade Glioma+6 more
Nationwide Children's Hospital15 enrolled18 locationsNCT06333899
Recruiting
Phase 2
Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
Metastatic Brain TumorGlioblastomaGlioblastoma Multiforme+7 more
Nationwide Children's Hospital120 enrolled21 locationsNCT05843253
Recruiting
Targeted Pediatric High-Grade Glioma Therapy
Metastatic Brain TumorGlioblastomaGlioblastoma Multiforme+6 more
Nationwide Children's Hospital350 enrolled21 locationsNCT05839379
Recruiting
Phase 3
A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma
Brain TumorGlioblastomaGBM+1 more
Ivy Brain Tumor Center450 enrolled93 locationsNCT06388733
Recruiting
Key Longitudinal Associations With Risk and Glioblastoma Outcomes
Glioblastoma
Duke University200 enrolled1 locationNCT06625684
Recruiting
Phase 2
Trial of Glioblastoma Immunotherapy Advancement With Nivolumab and Relatlimab
Newly Diagnosed Glioblastoma
Duke University92 enrolled1 locationNCT06816927
Recruiting
Phase 2
A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment
Glioblastoma Multiforme
Cedars-Sinai Medical Center170 enrolled5 locationsNCT05708352
Recruiting
Phase 2
A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial
Recurrent Glioblastoma
Duke University80 enrolled4 locationsNCT06069726
Recruiting
Phase 1
D2C7-IT + 2141-V11 Combination Post-resection in rGBM
Recurrent Glioblastoma, IDH-Wildtype
Darell Bigner46 enrolled1 locationNCT06455605
Recruiting
Phase 1Phase 2
D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients
Newly Diagnosed MGMT Unmethylated Glioblastoma
Darell Bigner50 enrolled1 locationNCT05734560
Recruiting
Phase 2Phase 3
A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma
Glioblastoma
Global Coalition for Adaptive Research1,280 enrolled62 locationsNCT03970447
Recruiting
Phase 2
Lerapolturev (PVSRIPO) in GBM
Recurrent Supratentorial Glioblastoma
Darell Bigner92 enrolled1 locationNCT06177964
Recruiting
Phase 1
Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma
GlioblastomaGBMGlioblastoma Multiforme+4 more
Orbus Therapeutics, Inc.66 enrolled8 locationsNCT05879367
Recruiting
Phase 1
Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults
GlioblastomaMalignant GliomaRecurrent Glioblastoma+3 more
Sabine Mueller, MD, PhD20 enrolled20 locationsNCT04323046