Glioblastoma Clinical Trials in Boston, Massachusetts

31 recruitingBoston, Massachusetts

Showing 120 of 31 trials

Recruiting
Phase 2

Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma

GlioblastomaGBM
Alpheus Medical, Inc.103 enrolled8 locationsNCT07225621
Recruiting
Phase 2

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Recurrent GlioblastomaProgressive Glioblastoma
National Cancer Institute (NCI)184 enrolled317 locationsNCT06325683
Recruiting
Phase 3

EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

Glioblastoma
NovoCure GmbH741 enrolled82 locationsNCT06556563
Recruiting
Phase 1

Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM

Glioblastoma
Dana-Farber Cancer Institute56 enrolled2 locationsNCT02287428
Recruiting
Early Phase 1

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

GlioblastomaGlioblastoma MultiformeHigh Grade Glioma+6 more
Nationwide Children's Hospital15 enrolled18 locationsNCT06333899
Recruiting
Phase 1

CUE-102 in Recurrent Glioblastoma

GlioblastomaGlioma, MalignantRecurrent Glioblastoma
David Reardon, MD18 enrolled2 locationsNCT06917885
Recruiting
Phase 2

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Metastatic Brain TumorGlioblastomaGlioblastoma Multiforme+7 more
Nationwide Children's Hospital120 enrolled21 locationsNCT05843253
Recruiting

Targeted Pediatric High-Grade Glioma Therapy

Metastatic Brain TumorGlioblastomaGlioblastoma Multiforme+6 more
Nationwide Children's Hospital350 enrolled21 locationsNCT05839379
Recruiting
Phase 2

Surgical Pembro +/- Olaparib w TMZ for rGBM

GlioblastomaRecurrent Glioblastoma
L. Nicolas Gonzalez Castro, MD, PhD78 enrolled4 locationsNCT05463848
Recruiting

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

Brain TumorBrain Tumor - MetastaticBrain Tumor, Recurrent+3 more
GT Medical Technologies, Inc.600 enrolled54 locationsNCT04427384
Recruiting
Phase 1

CARv3-TEAM-E T Cells in Glioblastoma

GlioblastomaMalignant GliomaRecurrent Glioblastoma+1 more
Marcela V. Maus, M.D.,Ph.D.21 enrolled1 locationNCT05660369
Recruiting
Phase 1Phase 2

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

Lung CancerNon-small Cell Lung CancerSolid Tumor+4 more
Tango Therapeutics, Inc.191 enrolled13 locationsNCT06810544
Recruiting
Phase 3

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Brain TumorGlioblastomaGBM+1 more
Ivy Brain Tumor Center450 enrolled93 locationsNCT06388733
Recruiting
Phase 1

A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

Recurrent Glioblastoma MultiformePrimary Glioblastoma MultiformeBrain Neoplasms, Malignant+1 more
AstraZeneca180 enrolled12 locationsNCT03423628
Recruiting
Phase 2

INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

Glioblastoma
Patrick Wen, MD460 enrolled12 locationsNCT02977780
Recruiting
Phase 2

G-CSF After Chemo-radiation in Patients With Glioblastoma

Glioblastoma (GBM)MGMT-Methylated GlioblastomaNewly Diagnosed Glioblastoma Multiforme
Massachusetts General Hospital60 enrolled1 locationNCT06649851
Recruiting
Phase 2

Enhanced Local Intensified Radiation Therapy in Elderly Glioblastoma: A Phase 2 Hybrid Randomized Trial

Glioblastoma (GBM)
Brigham and Women's Hospital56 enrolled3 locationsNCT06835803
Recruiting
Phase 2Phase 3

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Glioblastoma
Global Coalition for Adaptive Research1,280 enrolled62 locationsNCT03970447
Recruiting
Early Phase 1

A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma

Brain TumorGlioblastomaRecurrent Glioblastoma
Ugonma Chukwueke27 enrolled3 locationsNCT06552260
Recruiting
Not Applicable

Serial MRI Scans During Radiation Therapy

Esophageal CancerProstate CancerMRI+5 more
Dana-Farber Cancer Institute149 enrolled2 locationsNCT04188535