Glioblastoma Clinical Trials in Philadelphia, Pennsylvania

15 recruitingPhiladelphia, Pennsylvania

Showing 115 of 15 trials

Recruiting
Phase 2

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Recurrent GlioblastomaProgressive Glioblastoma
National Cancer Institute (NCI)184 enrolled317 locationsNCT06325683
Recruiting
Phase 1

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

Central Nervous System TumorGlioblastomaCNS Tumor+5 more
Sabine Mueller, MD, PhD208 enrolled6 locationsNCT04732065
Recruiting
Phase 3

EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

Glioblastoma
NovoCure GmbH741 enrolled82 locationsNCT06556563
Recruiting
Early Phase 1

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

GlioblastomaGlioblastoma MultiformeHigh Grade Glioma+6 more
Nationwide Children's Hospital15 enrolled18 locationsNCT06333899
Recruiting
Not Applicable

WBSI Guided Personalized Delivery of TTFields

GBMTumor, BrainGlioma Glioblastoma Multiforme
Abramson Cancer Center at Penn Medicine155 enrolled2 locationsNCT05086497
Recruiting

Targeted Pediatric High-Grade Glioma Therapy

Metastatic Brain TumorGlioblastomaGlioblastoma Multiforme+6 more
Nationwide Children's Hospital350 enrolled21 locationsNCT05839379
Recruiting
Phase 2

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Metastatic Brain TumorGlioblastomaGlioblastoma Multiforme+7 more
Nationwide Children's Hospital120 enrolled21 locationsNCT05843253
Recruiting
Phase 3

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Brain TumorGlioblastomaGBM+1 more
Ivy Brain Tumor Center450 enrolled93 locationsNCT06388733
Recruiting
Phase 1

Different Approaches for CART-EGFR-IL13Ra2 Dosing in Recurrent GBM

Recurrent Glioblastoma
University of Pennsylvania12 enrolled1 locationNCT07209241
Recruiting
Early Phase 1

Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of Glioblastoma

GlioblastomaRecurrent GlioblastomaGlioblastoma Multiforme of Brain
Abramson Cancer Center at Penn Medicine15 enrolled2 locationsNCT06613841
Recruiting

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

Breast CancerOvarian CancerEndometrial Cancer+40 more
Massive Bio, Inc.50,000 enrolled68 locationsNCT03452774
Recruiting
Phase 2Phase 3

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Glioblastoma
Global Coalition for Adaptive Research1,280 enrolled62 locationsNCT03970447
Recruiting
Phase 1

CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy

Glioblastoma
University of Pennsylvania9 enrolled1 locationNCT06973096
Recruiting
Phase 1

Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults

GlioblastomaMalignant GliomaRecurrent Glioblastoma+3 more
Sabine Mueller, MD, PhD20 enrolled20 locationsNCT04323046
Recruiting
Phase 2

A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence

Glioblastoma
Philogen S.p.A.90 enrolled8 locationsNCT06336291