Phase 2 Glucose Clinical Trials

17 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 117 of 17 trials

Recruiting
Phase 2

Regulation of Endogenous Glucose Production by Central KATP Channels

Diabetes MellitusGlucose Metabolism Disorders
Albert Einstein College of Medicine100 enrolled1 locationNCT03540758
Recruiting
Phase 2

Efficacy and Safety of Oral Controlled-release Nicotinic Acid (CIR-NA) for the Remission of Prediabetes. (CONCEPT)

Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
University Hospital Schleswig-Holstein390 enrolled2 locationsNCT07286747
Recruiting
Phase 1Phase 2

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Recruiting
Phase 2

Empagliflozin on Residual Kidney Function in Incident Peritoneal Dialysis Patients

End Stage Renal Disease on DialysisPeritoneal Dialysis ComplicationResidual Kidney Function+1 more
Chinese University of Hong Kong48 enrolled1 locationNCT06483074
Recruiting
Phase 2

Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver DiseaseImpaired Glucose ToleranceType 2 Diabetes Mellitus+1 more
Yale University60 enrolled1 locationNCT05067621
Recruiting
Phase 2Phase 3

Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes

Pregnancy ComplicationsGlucose Metabolism DisordersDiabetes, Gestational+1 more
Jaeb Center for Health Research30 enrolled5 locationsNCT06535789
Recruiting
Phase 2

GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance

Cystic FibrosisDiabetesPancreatic Insufficiency+1 more
University of Pennsylvania30 enrolled2 locationsNCT04731272
Recruiting
Phase 1Phase 2

An Open-Label, FIH Study Evaluating the Safety, Tolerability, and Efficacy of VCTX211 Combination Product in Subjects With T1D

Diabetes MellitusMetabolic DiseaseDiabetes Mellitus, Type 1+4 more
CRISPR Therapeutics AG40 enrolled2 locationsNCT05565248
Recruiting
Phase 2

Elucidating the Effects of Tocotrienol rich Vitamin E on Metabolic Biomarkers in a Pre-diabetes Population in Malaysia.

PrediabetesImpaired Glucose ToleranceImpaired fasting glucose
Monash University Malaysia80 enrolled2 locationsACTRN12622000256774
Recruiting
Phase 2

The effect of Virgin coconut oil on quality of life and serum lipid profile, glucose level and Hs Crp among acute coronary syndrome patients

Level of lipid profileLevel of glucose (fasting blood sugar and Hba1c)Level of Hs crp
MOSTI160 enrolled1 locationACTRN12618000752268
Completed
Phase 2

Investigating the effect of a soluble seaweed dietary fibre on gut, metabolic and skin health.

Keratoderma/psoriatic skin conditionIncreased Chronic InflammationImpaired Glucose Tolerance and Insulin resistance+2 more
University of Wollongong80 enrolled1 locationACTRN12617001010381
Recruiting
Phase 2

Does exogenous glucose-dependent insulinotropic polypeptide (GIP) effect gastric emptying and glycaemic response to small intestinal nutrient in critically ill patients?

Blood Glucose Control
Adam Deane25 enrolled1 locationACTRN12612000488808
Completed
Phase 2Phase 3

Clinical trial of a Chinese herbal medicine for the treatment of prediabetes and mild diabetes

Mild diabetes defined as those with diabetes diagnosed within 5 yrs of enrolment in the clinical trial, diet and exercise controlled and not taking any medications.Impaired glucose tolerance defined as having a fasting blood glucose <7.8 mmol and a 2 hour post prandial blood glucose >7.8 but <11.00
Xiyuan Hospital100 enrolled1 locationACTRN12612000128897
Completed
Phase 2

Does exogenous glucose-dependent insulinotropic polypeptide (GIP) in combination with glucagon-like peptide-1 (GLP-1) attenuate the glycaemic response to small intestinal nutrient in critically ill patients?

Blood Glucose
Adam Deane20 enrolled1 locationACTRN12611000735954
Completed
Phase 2

Efficacy of mulberry, red ginseng and banaba in the regulation of blood glucose and insulin responses in type 2 diabetes

Impaired glucose tolerence
Sookmyung Women's University94 enrolled1 locationACTRN12611000655943
Completed
Phase 2

Does exogenous glucagon-like peptide-1 (GLP-1) attenuates the glycaemic response to small intestinal nutrient in critically ill patients with pre-existing type-2 diabetes?

Blood Glucose
Adam Deane10 enrolled1 locationACTRN12610000185066
Completed
Phase 2

Exogenous glucagon-like peptide-1 (GLP-1) attenuates the glycaemic response to small intestinal nutrient in the critically ill.

Blood Glucose
Adam Deane8 enrolled1 locationACTRN12609000093280