Heart Failure NYHA Class II Clinical Trials

7 recruiting

Frequently Asked Questions

Common questions about Heart Failure NYHA Class II clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 113 of 13 trials

Recruiting
Phase 1

Autologous Induced Pluripotent Stem Cells of Cardiac Lineage for Congenital Heart Disease

Congenital Heart DiseaseHeart Failure NYHA Class IIIHeart Failure NYHA Class IV+1 more
HeartWorks, Inc.50 enrolled1 locationNCT05647213
Recruiting
Not Applicable

Sustaining Home Heart Failure Palliative Care in Rural Appalachia

Heart Failure NYHA Class IIIHeart Failure NYHA Class IV
West Virginia University208 enrolled1 locationNCT06791850
Recruiting
Phase 2Phase 3

Optimizing HFrEF Patients Using BaroStim and CardioMems

Heart Failure NYHA Class III
Northwell Health15 enrolled1 locationNCT07399587
Recruiting
Not Applicable

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Heart FailureHeart Failure NYHA Class IIIHeart Failure NYHA Class II
Endotronix, Inc.1,750 enrolled49 locationsNCT05934487
Recruiting

Real World Effectiveness of the Cordella Pulmonary Artery Sensor System in Patients With Chronic Heart Heart Failure

Heart FailureHeart Failure NYHA Class III
Endotronix, Inc.2,150 enrolled1 locationNCT06783335
Recruiting
Not Applicable

An Early Feasibility Study Evaluation of an Implant Free Interatrial Shunt to Improve Heart Failure

Heart FailureHeart Failure With Reduced Ejection FractionHeart Failure NYHA Class III+1 more
InterShunt Technologies, Inc.20 enrolled6 locationsNCT06859970
Recruiting

Association Between the Sit-To-Stand Test and the Prognosis of Patients With Heart Failure

Heart FailureHeart Failure NYHA Class IIIHeart Failure NYHA Class IV+2 more
Centro Universitário Augusto Motta68 enrolled1 locationNCT07045649
Recruiting
Not Applicable

Baduanjin-eight-silken-movement With Self-efficacy Building for Patients With Chronic Heart Failure (BESMILE-HF Study)

Heart FailureHeart Failure NYHA Class IIIHeart Failure NYHA Class II
Guangdong Provincial Hospital of Traditional Chinese Medicine150 enrolled1 locationNCT03180320
Recruiting
Not Applicable

Promoting Well-being and Health in Heart Failure

Heart FailureHeart Failure NYHA Class IIIHeart Failure NYHA Class II+1 more
Massachusetts General Hospital280 enrolled1 locationNCT04829617
Recruiting
Not Applicable

Comprehensive Hybrid Cardiac Rehabilitation Trial on Heart Failure

Heart Failure NYHA Class IIIHeart Failure NYHA Class II
Universidad de La Frontera152 enrolled4 locationsNCT06313684
Recruiting
Not Applicable

A Preventive, Multidisciplinary Primary Care Intervention Organized Around a Therapeutic Garden: Acceptability to Patients Suffering from Cardio-neurovascular Pathology and to Those Involved in the Action.

CardiomyopathiesStroke, IschemicAtrial Fibrillation (AF)+4 more
Assistance Publique Hopitaux De Marseille157 enrolled1 locationNCT06646601
Recruiting
Not Applicable

Atrial Appendage Micrograft Transplants to Assist Heart Repair After Cardiac Surgery

Coronary Artery DiseaseHeart Failure NYHA Class IIIHeart Failure NYHA Class IV+4 more
Hospital District of Helsinki and Uusimaa50 enrolled1 locationNCT05632432
Recruiting
Not Applicable

Study of the Clinical Impact of Surgical Correction of Tricuspid Insufficiency in Implantable LVAD Patients

Tricuspid RegurgitationHeart Failure NYHA Class IIIHeart Failure NYHA Class IV
University of Washington40 enrolled1 locationNCT02537769