Phase 2 Heart Clinical Trials
120 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 120 trials
Recruiting
Phase 2
Exploratory Study of ADR-002K for Heart Failure Patients With Ischemic Heart Disease Who Undergo CABG
Ischemic Heart Disease
Rohto Pharmaceutical Co., Ltd.50 enrolled1 locationNCT07192211
Recruiting
Phase 2
Transition to KPL-387 Monotherapy Dosing & Administration Study
PericarditisHeart DiseasesRecurrent Pericarditis
Kiniksa Pharmaceuticals International, plc80 enrolled32 locationsNCT07288216
Recruiting
Phase 2
Matching Perfusion and Metabolic Activity in HFpEF
Heart Failure With Preserved Ejection Fraction
University of Pennsylvania53 enrolled1 locationNCT04913805
Recruiting
Phase 2
Phase II Clinical Study of HRS-9057 Injection in Patients With Heart Failure-induced Fluid Retention
Fluid Retention Caused by Heart Failure
Fujian Shengdi Pharmaceutical Co., Ltd.153 enrolled1 locationNCT07318103
Recruiting
Phase 2
Comparative Study on the Mode of Action of Vicadrostat and Spironolactone on Protein Profiles and Renal Hemodynamic Effects (COMPARE-VS)
Heart FailureCardiovascular DiseasesCKD
University Medical Center Groningen100 enrolled2 locationsNCT07304817
Recruiting
Phase 2Phase 3
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Heart FailureLeft Ventricular Systolic Dysfunction
Merck Sharp & Dohme LLC342 enrolled106 locationsNCT05714085
Recruiting
Phase 2
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
Symptomatic Heart Failure With Preserved Ejection Fraction (HFpEF)
Cytokinetics60 enrolled25 locationsNCT06793371
Recruiting
Phase 2
A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
Heart Failure
Pfizer620 enrolled142 locationsNCT06991257
Recruiting
Phase 2
Single or Repeated Intravenous Administration of umbiliCAl Cord Mesenchymal sTrOmal Cells in Ischemic Cardiomyopathy
Ischemic Heart Disease
Roberto Bolli60 enrolled3 locationsNCT06145035
Recruiting
Phase 2
A Phase II Clinical Trial of HRS-1893 in the Treatment of Heart Failure With Preserved Ejection Fraction
Heart Failure With Preserved Ejection Fraction
Shandong Suncadia Medicine Co., Ltd.48 enrolled1 locationNCT07269717
Recruiting
Phase 2
Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
Heart Failure
Bristol-Myers Squibb208 enrolled117 locationsNCT06122779
Recruiting
Phase 2
CAMEO-FONTAN -Dapagliflozin in the Failing Fontan Circulation
HFpEF - Heart Failure With Preserved Ejection FractionFontan CirculationSingle Ventricle Heart Disease
Mayo Clinic27 enrolled1 locationNCT06762964
Recruiting
Phase 2
The Inorganic Nitrate and eXercise Performance in Heart Failure (iNIX-HF)
Heart Failure
Washington University School of Medicine75 enrolled1 locationNCT05562167
Recruiting
Phase 2
Repurposing Valsartan May Protect Against Pulmonary Hypertension
Pulmonary Arterial HypertensionRight Ventricular DysfunctionRight Heart Failure+1 more
University of Washington60 enrolled1 locationNCT06053580
Recruiting
Phase 2
Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation
Acute Kidney InjuryHeart Transplantation
Fernando Bacal74 enrolled1 locationNCT05909150
Recruiting
Phase 2
Coronary Artery Stents in Heart Failure With Preserved Ejection Fraction
Coronary Artery DiseaseHeart Failure With Preserved Ejection Fraction (HFpEF)
King's College London350 enrolled1 locationNCT07560436
Recruiting
Phase 2
A Study of 68Ga-Fibroblast Activation Protein Inhibitor (FAPI) Positron Emission Tomography in Heart Failure
Heart Failure With Preserved Ejection Fraction
Mayo Clinic35 enrolled1 locationNCT07083011
Recruiting
Phase 2
SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial
Heart Failure With Preserved Ejection Fraction
University of Pennsylvania53 enrolled1 locationNCT05138575
Recruiting
Phase 1Phase 2
Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease
Heart FailureChronic Kidney DiseasesKidney Diseases+1 more
Northwestern University60 enrolled1 locationNCT05719714
Recruiting
Phase 1Phase 2
Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children
Mechanical VentilationCongenital Heart DiseaseChildren+8 more
Charite University, Berlin, Germany80 enrolled1 locationNCT07193719