Phase 2 Heart Clinical Trials
116 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 116 trials
Recruiting
Phase 2
A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
Heart Failure
Pfizer620 enrolled135 locationsNCT06991257
Recruiting
Phase 2
A Study of 68Ga-Fibroblast Activation Protein Inhibitor (FAPI) Positron Emission Tomography in Heart Failure
Heart Failure With Preserved Ejection Fraction
Mayo Clinic35 enrolled1 locationNCT07083011
Recruiting
Phase 2Phase 3
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Heart FailureLeft Ventricular Systolic Dysfunction
Merck Sharp & Dohme LLC342 enrolled105 locationsNCT05714085
Recruiting
Phase 2
Transition to KPL-387 Monotherapy Dosing & Administration Study
PericarditisHeart DiseasesRecurrent Pericarditis
Kiniksa Pharmaceuticals International, plc80 enrolled12 locationsNCT07288216
Recruiting
Phase 2
SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial
Heart Failure With Preserved Ejection Fraction
University of Pennsylvania53 enrolled1 locationNCT05138575
Recruiting
Phase 2
Comparative Study on the Mode of Action of Vicadrostat and Spironolactone on Protein Profiles and Renal Hemodynamic Effects (COMPARE-VS)
Heart FailureCardiovascular DiseasesCKD
University Medical Center Groningen100 enrolled2 locationsNCT07304817
Recruiting
Phase 1Phase 2
Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease
Heart FailureChronic Kidney DiseasesKidney Diseases+1 more
Northwestern University60 enrolled1 locationNCT05719714
Recruiting
Phase 2
Phase II Clinical Study of HRS-9057 Injection in Patients With Heart Failure-induced Fluid Retention
Fluid Retention Caused by Heart Failure
Fujian Shengdi Pharmaceutical Co., Ltd.153 enrolled1 locationNCT07318103
Recruiting
Phase 1Phase 2
Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children
Mechanical VentilationCongenital Heart DiseaseChildren+8 more
Charite University, Berlin, Germany80 enrolled1 locationNCT07193719
Recruiting
Phase 2
CRF2 Agonist for the Treatment of Worsening Heart Failure
Worsening Heart Failure
Corteria Pharmaceuticals300 enrolled55 locationsNCT06815471
Recruiting
Phase 2
Belatacept in Heart Transplantation
Heart Transplant
National Institute of Allergy and Infectious Diseases (NIAID)66 enrolled5 locationsNCT06478017
Recruiting
Phase 2
Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetes
Heart FailureType 1 Diabetes
University of Dundee320 enrolled17 locationsNCT06435156
Recruiting
Phase 2
A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)
Pulmonary HypertensionHeart Failure With Preserved Ejection Fraction
Tectonic Therapeutic180 enrolled86 locationsNCT06616974
Recruiting
Phase 2Phase 3
Medication Withdrawal in Stable HF With Improved LVEF
Heart Failure
Hospital de Clinicas de Porto Alegre90 enrolled1 locationNCT07489547
Recruiting
Phase 1Phase 2
A Study on Yiyang Huoluo Decoction in the Treatment of Coronary Heart Disease
Coronary Heart DiseaseCoronary Artery DiseaseAtheroscleroses
Xia Liang30 enrolled1 locationNCT07493603
Recruiting
Phase 2
Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome
Heart FailureAcute Kidney Injury
Yale University130 enrolled2 locationsNCT07273838
Recruiting
Phase 2
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Heart Failure
Novo Nordisk A/S200 enrolled109 locationsNCT06979362
Recruiting
Phase 1Phase 2
Treating Heart Dysfunction Related to Cancer Therapy With Sacubitril/Valsartan
Heart FailureHeart Dysfunction
Virginia Commonwealth University53 enrolled1 locationNCT05194111
Recruiting
Phase 2
A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular Hypertrophy
Heart Failure
Novo Nordisk A/S200 enrolled92 locationsNCT06979375
Recruiting
Phase 2Phase 3
Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT)
Pulmonary HypertensionRheumatic Valvular Heart Disease
Sindh Institute of Cardiovascular Diseases100 enrolled1 locationNCT07462260