Phase 3 HIES Clinical Trials

10 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 110 of 10 trials

Recruiting
Phase 3

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company587 enrolled101 locationsNCT06563895
Recruiting
Phase 3

CMP-MYTHiC Trial and Registry - CardioMyoPathy With MYocarditis THerapy With Colchicine

Heart FailureCardiomyopathiesMyocarditis+2 more
Niguarda Hospital80 enrolled10 locationsNCT06158698
Recruiting
Phase 3

A Phase 3 Study of NTLA-2001 in ATTRv-PN

Nervous system diseasePeripheral nervous system diseaseAmyloidosis+17 more
Intellia Therapeutics60 enrolled14 locationsNCT06672237
Recruiting
Phase 3

MHB018A Treatment in Patients With Active Thyroid Eye Disease

Thyroid Associated Ophthalmopathies
Minghui Pharmaceutical (Hangzhou) Ltd108 enrolled1 locationNCT06989918
Recruiting
Phase 3

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

DementiaBrain DiseasesCentral Nervous System Diseases+6 more
Eli Lilly and Company1,500 enrolled141 locationsNCT05508789
Recruiting
Phase 3

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

Heart FailureDiabetes Mellitus, Type 1Diabetic Nephropathies+1 more
Alessandro Doria150 enrolled19 locationsNCT06217302
Recruiting
Phase 3

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Beta-ThalassemiaSickle Cell DiseaseHematologic Diseases+4 more
Vertex Pharmaceuticals Incorporated26 enrolled6 locationsNCT05477563
Recruiting
Phase 2Phase 3

Tailored Exercise Training Study Among Adults With HFpEF

Diabetic CardiomyopathiesHFpEF - Heart Failure With Preserved Ejection Fraction
University of Texas Southwestern Medical Center120 enrolled1 locationNCT07223242
Recruiting
Phase 3

Cardioprotective Effects of Melatonin in Patients With Cardiomyopathy

Cardiomyopathies
Tanta University46 enrolled1 locationNCT06846086
Recruiting
Phase 2Phase 3

Clinical Outcome of Vinpocetine in Diabetic Nephropathy

Diabetic Kidney DiseaseDiabetic Nephropathies
Ain Shams University64 enrolled2 locationsNCT06441591