IBS - Irritable Bowel Syndrome Clinical Trials

17 recruitingLast updated: June 18, 2026

There are 17 actively recruiting ibs - irritable bowel syndrome clinical trials across 10 countries. Studies span Not Applicable, Phase 3, Phase 2, Early Phase 1. Top locations include Los Angeles, California, United States, Bolingbrook, Illinois, United States, Braga, Portugal. Updated daily from ClinicalTrials.gov.


IBS - Irritable Bowel Syndrome Trials at a Glance

17 actively recruiting trials for ibs - irritable bowel syndrome are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 8 trials, with the heaviest enrollment activity in Los Angeles, Bolingbrook, and Braga. Lead sponsors running ibs - irritable bowel syndrome studies include Biocodex, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, and American Laboratory Products Company.

Browse ibs - irritable bowel syndrome trials by phase

Treatments under study

About IBS - Irritable Bowel Syndrome Clinical Trials

Looking for clinical trials for IBS - Irritable Bowel Syndrome? There are currently 17 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new IBS - Irritable Bowel Syndrome trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about IBS - Irritable Bowel Syndrome clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting
Not Applicable

A Study Evaluating the Impact of Regular FODMAP-targeting Digestive Enzyme Blend Use on Gastrointestinal Symptoms in Individuals With Self-Reported Bloating

Gut healthIBS - Irritable Bowel SyndromeAbdominal Pain+1 more
Kiwi Health Inc150 enrolled1 locationNCT07591584
Recruiting
Not Applicable

NCWS or IBS/FD in Relatives of CD Patients

Celiac DiseaseIBS - Irritable Bowel SyndromeFunctional Dyspepsia+1 more
University of Palermo600 enrolled2 locationsNCT07584473
Recruiting
Not Applicable

Sucrase-Isomaltase (SI) Genes and Meal Load

IBS - Irritable Bowel SyndromeSucrase-Isomaltase Deficiency
Region Skane70 enrolled1 locationNCT07309601
Recruiting
Not Applicable

A Prospective Trial of a Variable Compression System for Moderate to Severe Irritable Bowel Syndrome

IBS - Irritable Bowel Syndrome
PGP Health20 enrolled3 locationsNCT07540312
Recruiting
Phase 2

Efficacy of Rifaximin With NAC in IBS-D

IBS - Irritable Bowel SyndromeIBS-D (Diarrhea-predominant)
Mark Pimentel, MD225 enrolled1 locationNCT06727422
Recruiting

Gut Microbiome in Patients With Post-infectious Irritable Bowel Syndrome

IBS - Irritable Bowel SyndromePost Infection Syndrome
Fondazione Policlinico Universitario Agostino Gemelli IRCCS315 enrolled1 locationNCT07517029
Recruiting
Phase 3

Ebastine Versus Mebeverine in IBS Patients

IBS - Irritable Bowel SyndromeIBS
Guy Boeckxstaens200 enrolled5 locationsNCT05815602
Recruiting
Not Applicable

Study Evaluating the Efficacy of Different Mixes of HMO-2FL + Humiome® Post LB on IBS Gastrointestinal Symptoms

IBS - Irritable Bowel Syndrome
dsm-firmenich Switzerland AG402 enrolled12 locationsNCT06889779
Recruiting

ALPCO/Calprotectin CLIA Assay: Expected Values of Calprotectin in Healthy Subjects

IBD (Inflammatory Bowel Disease)Crohn Disease (CD)IBS - Irritable Bowel Syndrome+1 more
American Laboratory Products Company120 enrolled1 locationNCT07089420
Recruiting
Early Phase 1

Novel Pilot Study to Treat Symptoms of IBS With Diarrhea Using Combination Therapy of a Low-FODMAP Diet and a Neuromodulator

DiarrheaIBS - Irritable Bowel Syndrome
Mayo Clinic20 enrolled1 locationNCT06684470
Recruiting
Not Applicable

Lf-rTMS Attenuates Visceral Pain in Irritable Bowel Syndrome With Diarrhea

IBS - Irritable Bowel SyndromeFunctional Magnetic Resonance ImagingRepetitive Transcranial Magnetic Stimulation+2 more
The First Affiliated Hospital of Soochow University42 enrolled1 locationNCT06757491
Recruiting
Phase 3

Saccharomyces Boulardii CNCM I-745 in Irritable Bowel Syndrome

IBS - Irritable Bowel SyndromeIBS-D (Diarrhea-predominant)IBS, Mixed Symptoms
Biocodex406 enrolled10 locationsNCT07168434
Recruiting
Not Applicable

Evaluating the Impact of Including Virtual Dietary Education Within an Electronic Irritable Bowel Syndrome Pathway

IBS - Irritable Bowel Syndrome
Nova Scotia Health Authority76 enrolled1 locationNCT05721742
Recruiting
Phase 2

The Use of Directed Probiotics in ME/CFS: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

ME/CFSIBS - Irritable Bowel Syndrome
Nova Southeastern University100 enrolled1 locationNCT06211062
Recruiting
Not Applicable

Microbiota, Metabolome and Nutrition: an 'Artificially Intelligent' Way to Personalized Nutrition

IBS - Irritable Bowel Syndrome
Istituto Clinico Humanitas48 enrolled1 locationNCT06420843
Recruiting

Capsule Microbiota Sampling in IBS/Functional Gastrointestinal Disease

HealthyIBS - Irritable Bowel SyndromeFunctional Bloating+1 more
Stanford University40 enrolled1 locationNCT06215222
Recruiting
Phase 3

Ethosuximide and Pentoxifylline in the Treatment of Abdominal Pain Related to Irritable Bowel Syndrome

IBS - Irritable Bowel Syndrome
Tanta University60 enrolled1 locationNCT04217733