Phase 1 Immunotherapy Clinical Trials
18 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–18 of 18 trials
Recruiting
Phase 1
Efficacy and Safety of Autologous Peptide-induced Active Immunity in AML Maintenance Therapy
Acute Myeloid LeukemiaMaintenance TherapyPersonalized Active Immunotherapy
Fujian Medical University Union Hospital90 enrolled1 locationNCT07551037
Recruiting
Phase 1
VSV-02 Compassionate Use in Advanced Solid Tumors
Breast CancerLung CancerMelanoma+3 more
The First Affiliated Hospital of Xinxiang Medical College6 enrolled1 locationNCT07260591
Recruiting
Phase 1Phase 2
Personalized Neoantigen Peptide Vaccines for Solid Tumors
Solid TumorsAdvanced CancerRecurrent Cancer+2 more
Seqker Biosciences, Inc.10 enrolled2 locationsNCT07002203
Recruiting
Phase 1Phase 2
Hypofractionated Radiotherapy Combined With Immunochemotherapy for Conversion Treatment of Gastroesophageal Junction Adenocarcinoma
ChemotherapyGastroesophageal Junction AdenocarcinomaImmunotherapy+1 more
West China Hospital88 enrolled4 locationsNCT07072351
Recruiting
Phase 1Phase 2
A Study of ABT-301 Plus Tislelizumab With Bevacizumab in pMMR/Non-MSI-H Locally Advanced or mCRC
ImmunotherapyColorectal Cancer MetastaticColorectal Cancer (CRC)+1 more
Anbogen Therapeutics, Inc.66 enrolled15 locationsNCT07244705
Recruiting
Phase 1Phase 2
NEoadjuvant Chemotherapy and Immunotherapy for a Selected Group of Inoperable Pleural Mesothelioma Patients (NECIM): a Feasibility Study
Mesothelioma; PleuraNeoadjuvant ChemoimmunotherapyPleural Epithelioid Mesothelioma
University Hospital, Antwerp37 enrolled1 locationNCT07121374
Recruiting
Phase 1Phase 2
A Clinical Trial of Neoadjuvant Targeted Therapy, Immunotherapy, and Lysogenic HSV-Based Virotherapy in Resectable Head and Neck Squamous Cell Carcinoma
Neoadjuvant TherapyHNSCCTargeted Therapy+2 more
West China Hospital29 enrolled1 locationNCT07010120
Recruiting
Phase 1
A Phase I Trial of Tumor-Associated Lymph Node T-Cell Injection With Advanced Malignant Solid Tumors
Advanced Solid TumorImmunotherapyTumor Associated Lymph Node T Cell+1 more
Guangzhou FineImmune Biotechnology Co., LTD.32 enrolled1 locationNCT06716619
Recruiting
Phase 1Phase 2
Induction Toripalimab and Chemotherapy in Locally Advanced Cervical Cancer
Cervical CancerImmunotherapyInduction Chemotherapy
Tianjin Medical University Cancer Institute and Hospital20 enrolled1 locationNCT06093438
Recruiting
Phase 1
A Clinical Study on Neoadjuvant Treatment of Resectable Head and Neck Squamous Carcinoma With Immune-targeted Therapy and Lysogenic HSV Virus
Neoadjuvant TherapyHNSCCTargeted Therapy+2 more
West China Hospital21 enrolled1 locationNCT06741982
Recruiting
Phase 1
Phase I Clinical Study of Tumor-associated Lymph Node T Cell Therapy for Advanced Solid Tumors
Advanced Solid TumorImmunotherapyTumor Associated Lymph Node T Cell
Guangzhou FineImmune Biotechnology Co., LTD.23 enrolled1 locationNCT06302062
Recruiting
Phase 1
GPC3/Mesothelin/Claudin18.2/GUCY2C/B7-H3/PSCA/PSMA/MUC1/TGFβ/HER2/Lewis-Y/AXL/EGFR-CAR-T Cells Against Cancers
Lung CancerCancerImmunotherapy+1 more
Second Affiliated Hospital of Guangzhou Medical University30 enrolled2 locationsNCT03198052
Recruiting
Phase 1
GPC3-CAR-T Cells for Immunotherapy of Cancer With GPC3 Expression
Hepatocellular CarcinomaImmunotherapySquamous Cell Lung Cancer+3 more
Second Affiliated Hospital of Guangzhou Medical University30 enrolled2 locationsNCT03198546
Recruiting
Phase 1Phase 2
Induced-T Cell Like NK Cellular Immunotherapy for Cancer Lack of MHC-I
Anti-cancer Cell ImmunotherapyT Cell and NK Cell
Second Affiliated Hospital of Guangzhou Medical University60 enrolled1 locationNCT03882840
Recruiting
Phase 1Phase 2
Concurrent Chemoradiotherapy Followed by PD-1 Inhibitor in Advanced Cervical Cancer
Locally Advanced Cervical CarcinomaImmunotherapyConcurrent Chemoradiotherapy
RenJi Hospital20 enrolled1 locationNCT06391190
Recruiting
Phase 1
Clinical Study of PSMA-targeted CAR-T Cells in the Treatment of Castration-resistant Prostate Cancer
Immunotherapy
The Affiliated Hospital of Xuzhou Medical University20 enrolled1 locationNCT05354375
Recruiting
Phase 1
Hypomemylating Agents Combination With eDC Therapy for Elderly Patients With Myelodysplastic Syndrome
ImmunotherapyMyelodysplastic SyndromesDendritic Cell+1 more
Affiliated Hospital to Academy of Military Medical Sciences40 enrolled1 locationNCT04999943
Recruiting
Phase 1
Clinical Study of CAIX-targeted CAR-T Cells in the Treatment of Advanced Renal Cell Carcinoma
Immunotherapy
The Affiliated Hospital of Xuzhou Medical University20 enrolled1 locationNCT04969354