ClinicalTrialsFinder

Phase 1 Influenza Clinical Trials

25 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–20 of 25 trials

Recruiting
Phase 1

Quadrivalent Influenza HA Stem Vaccine VRC-FLUMOS0122-00-VP (SteMos1) With and Without ALFQ Adjuvant in Healthy Adults

Influenza PreventionPandemic Influenza Prevention
National Institute of Allergy and Infectious Diseases (NIAID)56 enrolled1 locationNCT07111078
Recruiting
Phase 1

First-in-Human Study of VNT-101: Safety, Tolerability, and Pharmacokinetics

Influenza
National Institute of Allergy and Infectious Diseases (NIAID)78 enrolled1 locationNCT07169318
Recruiting
Phase 1

pH1N1 Blinded Challenge Study

Influenza
National Institute of Allergy and Infectious Diseases (NIAID)90 enrolled2 locationsNCT07110532
Recruiting
Phase 1Phase 2

Safety and Immunogenicity of the Monovalent Influenza Vaccine A (H5N8) (Inactivated, Fragmented and Adjuvanted) in Adults and Older Adults

Avian Influenza A Virus
Butantan Institute700 enrolled5 locationsNCT06842173
Recruiting
Phase 1

Influenza Human Challenge Model

Influenza
Emory University80 enrolled2 locationsNCT05332899
Recruiting
Phase 1

A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults

Influenza, Human+COVID-19
GlaxoSmithKline225 enrolled2 locationsNCT07464314
Recruiting
Phase 1Phase 2

Phase 1/2 Study of a Plant-Based Seasonal Recombinant Trivalent VLP Influenza Vaccine

Influenza
Aramis Biotechnologies Inc.728 enrolled7 locationsNCT07291635
Not Yet Recruiting
Phase 1

A Randomized, Double-Blind, Placebo-Controlled, Dose Escalation Study of TRX-100 Tablets Evaluating the Safety, Pharmacokinetics, and Food Effect of Single Ascending Doses of TRX-100 in Healthy Volunteers

Influenza
Traws Pharma, Inc16 enrolled1 locationACTRN12626000272392
Recruiting
Phase 1

A Phase 1a/b Randomized, Double-Blind, Placebo-Controlled, Dose Escalation Study with an Open-Label Active-Controlled Phase, to Evaluate the Safety and Immunogenicity of Centi-Flu 01 in Healthy Adults 18 Years of Age and Older

Influenza
Centivax, Inc.180 enrolled2 locationsACTRN12626000259347
Recruiting
Phase 1

A/Texas Flu Challenge

Influenza
Emory University50 enrolled2 locationsNCT06753474
Recruiting
Phase 1

Evaluating the Dose, Safety, Tolerability, and Immunogenicity of Mosaic Hexavalent Influenza Vaccine VRCFLUMOS0116-00-VP (FluMos-v2) With and Without ALFQ Adjuvant in Healthy Adults

Influenza PreventionSeasonal Influenza
National Institute of Allergy and Infectious Diseases (NIAID)45 enrolled1 locationNCT06863142
Recruiting
Phase 1

A Clinical Trial of Influenza Virus Split Vaccine for Individuals Aged 60 Years and Above

Influenza
Shanghai Institute Of Biological Products120 enrolled1 locationNCT07302256
Not Yet Recruiting
Phase 1

A study in healthy young adults to compare how safe, well-tolerated, and effective INNA-051 is when given using either a single-use or a multi-use nasal spray system, and to understand participants’ experiences with each.

COVID-19InfluenzaCommon cold
ENA Respiratory Pty Ltd20 enrolled1 locationACTRN12626000037303
Recruiting
Phase 1

Clinical Trial of the Adsorbed Acellular Pertussis (Tricomponent) DTaP-Haemophilus Influenzae Type b (Conjugate)-ACYW135 Group Meningococcal (Conjugate) Combined Vaccine

Diphtheria, Tetanus and Acellular PertussisEpidemic MeningitisHaemophilus Influenzae Type B Infection
CanSino Biologics Inc.260 enrolled1 locationNCT07203755
Recruiting
Phase 1Phase 2

Clinical Trials of Quadrivalent Influenza Vaccine

Influenza, Human
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.620 enrolled1 locationNCT06824519
Recruiting
Phase 1

Covid-19 and Influenza Oral Vaccine Study

Influenza, Humancovid19 Infection
Vaxine Pty Ltd100 enrolled1 locationNCT06355232
Recruiting
Phase 1

First-in-human Safety and Immunogenicity Study of SCB-1022 and SCB-1033 in Healthy Older Adults

Respiratory Syncytial Virus VaccinationHuman Metapneumovirus VaccinationParainfluenza Vaccination
Clover Biopharmaceuticals AUS Pty192 enrolled1 locationNCT06984094
Recruiting
Phase 1

Study of the Safety, Tolerability, and Pharmacokinetic Profile of Ascending Doses of Ingavirin Forte, Capsules, Folliwing Single and Subsequent Multiple Oral Administration in Healthy Volunteers

InfluenzaViral Respiratory Infection
Valenta Pharm JSC36 enrolled1 locationNCT06859333
Recruiting
Phase 1

Study of the Infectivity, Safety and Immunogenicity of Two Recombinant, Live-Attenuated, B/HPIV3 Vectored Vaccines Expressing the Fusion Glycoprotein of HMPV Delivered by Nasal Spray to HPIV3-Seropositive Children 24 to <60 Months of Age

Human MetapneumovirusHuman Parainfluenza Virus Type 3
National Institute of Allergy and Infectious Diseases (NIAID)25 enrolled4 locationsNCT06546423
Completed
Phase 1

A Randomized, Double-Blind, Placebo-Controlled, Phase 1, Dose Escalation (with optional food effect) Study of Orally Administered TRX-100 to Evaluate the Safety, Tolerability and Pharmacokinetics of Single Ascending Doses of TRX-100 in Healthy Volunteers

Influenza
Trawsfynydd Therapeutics AU Pty Ltd (on behalf of Traws Pharma, Inc.)40 enrolled1 locationACTRN12624000891527