Phase 2 Insomnia Clinical Trials
20 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 20 trials
Recruiting
Phase 2
Sleep to Reduce Incident Depression Effectively in Peripartum
InsomniaDepression
Henry Ford Health System500 enrolled1 locationNCT06430333
Recruiting
Phase 1Phase 2
Mindfulness Meditation for Insomnia
InsomniaMindfulnessTelemedicine+2 more
Brigham and Women's Hospital30 enrolled1 locationNCT06972303
Recruiting
Phase 2
Resilience Enhancement Following Sleep Treatment
Chronic Low Back Pain (CLBP)Insomnia
University of Virginia300 enrolled1 locationNCT07298941
Recruiting
Phase 2
Efficacy of Trazodone to Treat Insomnia in Older Adults (TRADITION Study)
Older PeopleDrug TherapyInsomnia Chronic
Centre hospitalier de l'Université de Montréal (CHUM)40 enrolled1 locationNCT06983080
Not Yet Recruiting
Phase 2
Combination pharmacotherapy for co-morbid insomnia and obstructive sleep apnea (COMISA)
Comorbid sleep apnoea and insomnia (COMISA)
Monash University20 enrolled1 locationACTRN12625001289404
Not Yet Recruiting
Phase 2
An open label pilot trial of suvorexant for the management of comorbid insomnia and alcohol use disorder
InsomniaAlcohol Use Disorder
Eastern Health20 enrolled1 locationACTRN12625001226493
Recruiting
Phase 2
Comparing Telehealth-Delivered CBT-I to Web-Based CBT-I to Enhance Sleep, Reduce Fatigue, and Promote Neuroprotection
InsomniaMultiple Sclerosis
University of Kansas Medical Center90 enrolled1 locationNCT06434571
Recruiting
Phase 2
A Dual Orexin Receptor Antagonist to Reduce Biomarkers of Neurodegeneration in Adults With Insomnia.
Insomnia
Woolcock Institute of Medical Research20 enrolled1 locationNCT06823752
Recruiting
Phase 2
A Study to Evaluate Effects on Sleep and Safety of RE03 in PTSD Patients With Sleep Disturbances
Sleep Disturbances and InsomniaPosttraumatic Stress Disorder (PTSD)
Reconnect Labs24 enrolled1 locationNCT06685965
Recruiting
Phase 2
Suvorexant for Treatment of AUD and PTSD
InsomniaPost Traumatic Stress Disorder (PTSD)Alcohol Use Disorder (AUD)
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance76 enrolled2 locationsNCT06679062
Recruiting
Phase 2
Efficacy of Cognitive Behavioral Therapy for Insomnia to Treat Insomnia Symptoms in Individuals With Multiple Sclerosis
InsomniaMultiple Sclerosis
University of Kansas Medical Center70 enrolled1 locationNCT06428006
Recruiting
Phase 2
Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse
InsomniaTobacco UseTobacco Cessation
Yale University114 enrolled2 locationsNCT06609369
Recruiting
Phase 2Phase 3
Efficacy of Melatonin, Low-dose Quetiapine, or Placebo in Patients With Psychiatric Disorders and Comorbid Insomnia
InsomniaPsychiatric Disorders
Lone Baandrup255 enrolled1 locationNCT06062953
Recruiting
Phase 2
Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)
InsomniaCognitive DysfunctionAlzheimer Disease+6 more
University of Virginia144 enrolled1 locationNCT05565833
Recruiting
Phase 2
Assessing a live microbial therapy for the treatment of Insomnia
Insomnia
Servatus Ltd50 enrolled1 locationACTRN12621001413819
Not Yet Recruiting
Phase 2
A Randomised Controlled Trial of Treatment for Post-Concussion Clinical Insomnia in Children and Adolescents: The Effect of Melatonin Plus Sleep Hygiene Education Versus Education Alone
Post-Concussion Clinical Insomnia
The Children's Hospital Institute of Sports Medicine120 enrolled1 locationACTRN12619001585112
Completed
Phase 2
A single-dose, double-blind, placebo-controlled, randomised, crossover study of an oral cannabis-based medicine (ETC120) on sleep, cognition, and next-day function in adults with chronic insomnia disorder
Insomnia
Woolcock Institute of Medical Research20 enrolled1 locationACTRN12619000714189
Recruiting
Phase 2
A clinical trial assessing the efficacy and safety of Ziziphus spinosa seeds compared to placebo for people with insomnia
Insomnia
RMIT University12 enrolled1 locationACTRN12618001589279
Not Yet Recruiting
Phase 2
The effect of Chinese herbal medicine on sleep quality in stressed people suffering from insomnia
InsomniaStress
University of Technology Sydney20 enrolled1 locationACTRN12617000351314
Completed
Phase 2
Sleep Restriction Therapy + Armodafinil for Insomnia Disorder
Insomnia Disorder
Woolcock Institute of Medical Research, Sydney University30 enrolled1 locationACTRN12614001293651