Insomnia Clinical Trials

245 recruitingLast updated: June 17, 2026

There are 245 actively recruiting insomnia clinical trials across 31 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3, Early Phase 1, Phase 1. Top locations include Boston, Massachusetts, United States, Beijing, China, Beijing, Beijing Municipality, China. Updated daily from ClinicalTrials.gov.


Insomnia Trials at a Glance

245 actively recruiting trials for insomnia are listed on ClinicalTrialsFinder across 6 cities in 31 countries. The largest study group is Not Applicable with 165 trials, with the heaviest enrollment activity in Boston, Beijing, and Beijing. Lead sponsors running insomnia studies include Xuanwu Hospital, Beijing, University of South Florida, and The University of Hong Kong.

Treatments under study

About Insomnia Clinical Trials

Looking for clinical trials for Insomnia? There are currently 232 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Insomnia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Insomnia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 245 trials

Recruiting
Not Applicable

Digital Cognitive Behavioral Treatment of Insomnia in Youth: An RCT Examining Feasibility, Acceptability, and Efficacy of NiteCAPP Jr

Insomnia
University of South Florida40 enrolled1 locationNCT07091149
Recruiting
Not Applicable

Training in Evidence-based Treatments in Psycho-Oncology

PainDepression, AnxietyDistress, Emotional+2 more
Massachusetts General Hospital115 enrolled1 locationNCT05674357
Recruiting
Not Applicable

Web-based Cognitive Behavioral Treatment for Insomnia in Dementia Caregivers

DementiaInsomnia Chronic
University of South Florida60 enrolled1 locationNCT04632628
Recruiting
Phase 2

Efficacy of Cognitive Behavioral Therapy for Insomnia to Treat Insomnia Symptoms in Individuals With Multiple Sclerosis

InsomniaMultiple Sclerosis
University of Kansas Medical Center70 enrolled1 locationNCT06428006
Recruiting
Phase 4

Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms

InsomniaMenopausal Women
Brigham and Women's Hospital1,000 enrolled5 locationsNCT07136415
Recruiting
Phase 2

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

InsomniaTobacco UseTobacco Cessation
Yale University114 enrolled2 locationsNCT06609369
Recruiting
Phase 4

A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia

InsomniaChronic InsomniaInsomnia Disorder+1 more
University of Pennsylvania1,200 enrolled1 locationNCT07542756
Recruiting
Phase 3

Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia

Insomnia Disorder
Vanda Pharmaceuticals420 enrolled35 locationsNCT06953869
Recruiting
Not Applicable

Adapted CBT-I for Adolescents With Insomnia : The DREAM-IT Study

Insomnia
Indiana University28 enrolled1 locationNCT06541886
Recruiting
Not Applicable

Virtual Reality Relaxation for Insomnia

Insomnia Disorder
Laval University30 enrolled1 locationNCT07630532
Recruiting
Not Applicable

Clinical Efficacy and Health Economic Evaluation of an Intelligent Diagnostic and Treatment Model

Insomnia
Zan Wang200 enrolled1 locationNCT07357779
Recruiting
Not Applicable

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

InsomniaTraumatic Brain InjuryDepression+7 more
Johns Hopkins University360 enrolled5 locationsNCT05663034
Recruiting
Not Applicable

Targeting Insomnia to Improve Outcomes in Adults With Problematic Cannabis Use

Insomnia
University of Michigan200 enrolled1 locationNCT05814822
Recruiting
Not Applicable

ASV Therapy for Insomnia

InsomniaInsomnia (Moderate)
ResMed25 enrolled1 locationNCT07011966
Recruiting
Phase 3

A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)

Insomnia
Merck Sharp & Dohme LLC300 enrolled11 locationsNCT06655883
Recruiting
Not Applicable

Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients

Postoperative Neurocognitive DisorderInsomniaPostoperative Delirium+1 more
Massachusetts General Hospital50 enrolled1 locationNCT06375265
Recruiting

Sleep and Stroke Rehabilitation Study

InsomniaStrokeSleep Apnea Syndrome (OSAS)+1 more
Malin Eleonora av Kák Gustafsson, MD, PhD226 enrolled1 locationNCT07579871
Recruiting
Not Applicable

Digital CBT for Insomnia and Depression

InsomniaDepression
University of Rochester1,200 enrolled1 locationNCT05456607
Recruiting
Phase 2

Lemborexant for the Treatment of Residual Insomnia in Major Depressive Disorder (MDD)

Major Depressive Disorder (MDD)Insomnia Comorbid to Psychiatric Disorder
Unity Health Toronto30 enrolled1 locationNCT06843187
Recruiting
Not Applicable

A Hybrid Effectiveness Implementation Trial Evaluating Behavioral Treatments for Insomnia for Socioeconomically Disadvantaged Adults in Primary Care

Insomnia
Brigham and Women's Hospital350 enrolled1 locationNCT05759065